SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5na2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5na2 CAPSID PROTEIN (P24)
(Feline
immunodeficiency
virus) 		5 / 12 ILE A 135
ASP A  64
GLY A  32
GLY A  29
SER A 180
 None
 1.09A 1rjdA-5na2A:
undetectable		 1rjdA-5na2A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5na2 CAPSID PROTEIN (P24)
(Feline
immunodeficiency
virus) 		5 / 12 ILE A 135
ASP A  64
GLY A  32
GLY A  29
SER A 180
 None
 1.08A 1rjdB-5na2A:
undetectable		 1rjdB-5na2A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5na2 CAPSID PROTEIN (P24)
(Feline
immunodeficiency
virus) 		5 / 12 ILE A 135
ASP A  64
GLY A  32
GLY A  29
SER A 180
 None
 1.08A 1rjdC-5na2A:
undetectable		 1rjdC-5na2A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 5na2 CAPSID PROTEIN (P24)
(Feline
immunodeficiency
virus) 		5 / 12 LEU A 126
LEU A 129
LEU A 132
ALA A 133
ALA A  26
 None
 1.06A 4fn9A-5na2A:
undetectable		 4fn9A-5na2A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5na2 CAPSID PROTEIN (P24)
(Feline
immunodeficiency
virus) 		3 / 3 LEU A 203
TYR A 153
SER A 182
 None
 0.89A 5iktA-5na2A:
undetectable		 5iktA-5na2A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 5na2 CAPSID PROTEIN (P24)
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  46
PHE A  22
LEU A  54
ARG A 122
LEU A 129
 None
 1.21A 6ew0G-5na2A:
undetectable		 6ew0G-5na2A:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_1
(-)		 5na2 CAPSID PROTEIN (P24)
(Feline
immunodeficiency
virus) 		5 / 12 LEU A 129
LEU A  75
LEU A  72
MET A  51
PHE A  39
 None
 1.44A 6gbnC-5na2A:
undetectable		 6gbnC-5na2A:
19.46