SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5na7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 7 LYS A 326
SER A 398
SER A 400
THR A 402
 None
 0.88A 1dvxA-5na7A:
undetectable		 1dvxA-5na7A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 8 TYR A  88
PHE A 100
MET A 103
THR A 141
 None
 1.24A 1ea1A-5na7A:
undetectable		 1ea1A-5na7A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 8 SER A 217
ALA A 288
PHE A 284
ILE A 289
 None
 0.79A 1gm7A-5na7A:
undetectable
1gm7B-5na7A:
2.6		 1gm7A-5na7A:
14.61
1gm7B-5na7A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		3 / 3 ALA A 549
VAL A 544
TRP A 543
 None
 0.77A 1kqeA-5na7A:
undetectable
1kqeE-5na7A:
undetectable		 1kqeA-5na7A:
3.44
1kqeE-5na7A:
3.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		3 / 3 ALA A 549
VAL A 544
TRP A 543
 None
 0.75A 1kqeB-5na7A:
undetectable
1kqeD-5na7A:
undetectable		 1kqeB-5na7A:
3.44
1kqeD-5na7A:
3.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A 543
ALA A 549
VAL A 544
 None
 0.76A 1kqeB-5na7A:
undetectable
1kqeD-5na7A:
undetectable		 1kqeB-5na7A:
3.44
1kqeD-5na7A:
3.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A 543
ALA A 549
VAL A 544
 None
 0.74A 1kqeA-5na7A:
undetectable
1kqeE-5na7A:
undetectable		 1kqeA-5na7A:
3.44
1kqeE-5na7A:
3.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		5 / 7 ARG A 537
ILE A 540
LEU A 581
GLY A 578
PHE A 577
 None
 1.17A 1rtsB-5na7A:
undetectable		 1rtsB-5na7A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A  77
TYR A 106
SER A 113
 None
 0.91A 2gvcB-5na7A:
undetectable		 2gvcB-5na7A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A  77
TYR A 106
SER A 113
 None
 0.89A 2gvcE-5na7A:
undetectable		 2gvcE-5na7A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 7 THR A 518
GLY A 515
PHE A 419
THR A 510
 None
 0.93A 2vl2B-5na7A:
undetectable		 2vl2B-5na7A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 4 ALA A 506
TYR A 508
ALA A 503
TYR A 504
 None
 1.30A 2wlkA-5na7A:
undetectable
2wlkB-5na7A:
undetectable		 2wlkA-5na7A:
16.76
2wlkB-5na7A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 8 GLN A 265
LEU A 253
LYS A 254
LEU A  54
 None
 1.08A 2xn3A-5na7A:
undetectable
2xn3B-5na7A:
undetectable		 2xn3A-5na7A:
19.55
2xn3B-5na7A:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		3 / 3 HIS A 117
GLU A 123
HIS A 118
 None
 0.89A 3ba0A-5na7A:
undetectable		 3ba0A-5na7A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 157
ARG A  81
ASN A  90
 None
 0.68A 3qxvD-5na7A:
undetectable		 3qxvD-5na7A:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A  36
PRO A 378
LYS A 628
GLY A 629
 None
 1.10A 3tkdB-5na7A:
undetectable		 3tkdB-5na7A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A  36
PRO A 378
LYS A 628
GLY A 629
 None
 1.07A 3tkdA-5na7A:
undetectable		 3tkdA-5na7A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 441
ASP A 438
GLY A 437
HIS A 415
 None
 0.83A 4c5nA-5na7A:
2.2		 4c5nA-5na7A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY A 441
ASP A 438
GLY A 437
HIS A 415
 None
 0.83A 4c5nC-5na7A:
undetectable		 4c5nC-5na7A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		5 / 10 ILE A 540
LEU A 516
GLY A 515
PHE A 511
ASN A 514
 None
 1.38A 4eb4D-5na7A:
undetectable		 4eb4D-5na7A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 6 GLY A 239
GLY A 240
GLU A 247
ILE A 246
 None
 0.99A 4fglD-5na7A:
undetectable		 4fglD-5na7A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD6_A_TOYA501_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		5 / 9 PHE A  70
ASP A  67
ILE A  68
TRP A 319
TYR A 656
 None
 1.13A 4jd6A-5na7A:
0.0		 4jd6A-5na7A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD6_B_TOYB501_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		5 / 9 PHE A  70
ASP A  67
ILE A  68
TRP A 319
TYR A 656
 None
 1.15A 4jd6B-5na7A:
0.0		 4jd6B-5na7A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 410
THR A 306
LEU A 386
THR A 402
 None
None
CL  A 704 ( 4.0A)
None
 1.48A 4mbsB-5na7A:
undetectable		 4mbsB-5na7A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A 318
GLY A 374
ALA A 373
GLU A 320
 None
 0.89A 4r1zB-5na7A:
undetectable		 4r1zB-5na7A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A 406
LEU A 372
GLY A 629
LYS A 628
 None
 0.97A 4z69A-5na7A:
1.8		 4z69A-5na7A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 5 PHE A 511
ILE A 540
GLN A 519
ARG A 537
 None
 1.40A 5jm4A-5na7A:
undetectable		 5jm4A-5na7A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A  71
ASN A 190
ASP A 193
 None
 0.75A 5vopA-5na7A:
undetectable		 5vopA-5na7A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A  71
ASN A 190
ASP A 193
 None
 0.78A 5vopB-5na7A:
undetectable		 5vopB-5na7A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 8 HIS A 117
ASP A 193
TYR A 191
LEU A 241
 None
 1.10A 5w97A-5na7A:
1.2
5w97C-5na7A:
undetectable
5w97c-5na7A:
undetectable		 5w97A-5na7A:
21.17
5w97C-5na7A:
15.94
5w97c-5na7A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 241
HIS A 117
ASP A 193
TYR A 191
 None
 1.12A 5w97C-5na7A:
undetectable
5w97a-5na7A:
1.1
5w97c-5na7A:
undetectable		 5w97C-5na7A:
15.94
5w97a-5na7A:
21.17
5w97c-5na7A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 8 HIS A 117
ASP A 193
TYR A 191
LEU A 241
 None
 1.12A 5x19A-5na7A:
1.1
5x19C-5na7A:
undetectable
5x19P-5na7A:
undetectable		 5x19A-5na7A:
21.17
5x19C-5na7A:
15.94
5x19P-5na7A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 7 HIS A 117
ASP A 193
TYR A 191
LEU A 241
 None
 1.11A 5x1bA-5na7A:
undetectable
5x1bC-5na7A:
undetectable
5x1bP-5na7A:
undetectable		 5x1bA-5na7A:
21.17
5x1bC-5na7A:
15.94
5x1bP-5na7A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 7 HIS A 117
ASP A 193
TYR A 191
LEU A 241
 None
 1.10A 5x1fA-5na7A:
1.2
5x1fC-5na7A:
undetectable
5x1fP-5na7A:
undetectable		 5x1fA-5na7A:
21.17
5x1fC-5na7A:
15.94
5x1fP-5na7A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A 520
VAL A 615
GLU A 614
LEU A 611
 None
 1.10A 5xooB-5na7A:
undetectable		 5xooB-5na7A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A 241
HIS A 117
ASP A 193
TYR A 191
 None
 1.05A 6nknC-5na7A:
undetectable
6nknN-5na7A:
undetectable
6nknP-5na7A:
undetectable		 6nknC-5na7A:
15.94
6nknN-5na7A:
21.17
6nknP-5na7A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5na7 PUTATIVE
DIPEPTIDYL-PEPTIDASE
III
(Bacteroides
thetaiotaomicron) 		4 / 7 HIS A 117
ASP A 193
TYR A 191
LEU A 241
 None
 1.08A 6nmfA-5na7A:
1.3
6nmfC-5na7A:
undetectable
6nmfP-5na7A:
undetectable		 6nmfA-5na7A:
21.17
6nmfC-5na7A:
15.94
6nmfP-5na7A:
15.94