SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5naq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5naq BETA-GALACTOSIDASE
(Lactobacillus
plantarum) 		3 / 3 GLU A  20
THR A  19
LEU A  73
 None
 0.51A 1v8bC-5naqA:
undetectable		 1v8bC-5naqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 5naq BETA-GALACTOSIDASE
(Lactobacillus
plantarum) 		4 / 5 ALA A 239
TYR A 321
ALA A 235
GLN A 314
 None
 1.14A 1xl6A-5naqA:
undetectable
1xl6B-5naqA:
undetectable		 1xl6A-5naqA:
22.02
1xl6B-5naqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5naq BETA-GALACTOSIDASE
(Lactobacillus
plantarum) 		4 / 6 ILE A 115
THR A  19
PHE A  98
TYR A  99
 None
 1.21A 3elzB-5naqA:
undetectable		 3elzB-5naqA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 5naq BETA-GALACTOSIDASE
(Lactobacillus
plantarum) 		5 / 12 GLY A  16
GLN A  78
PHE A 153
ILE A 115
ASN A 164
 None
 1.14A 4fr0A-5naqA:
undetectable		 4fr0A-5naqA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 5naq BETA-GALACTOSIDASE
(Lactobacillus
plantarum) 		3 / 3 ASP A 121
TRP A 415
SER A  76
 None
 1.05A 4lrhB-5naqA:
undetectable		 4lrhB-5naqA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 5naq BETA-GALACTOSIDASE
(Lactobacillus
plantarum) 		4 / 8 LEU A 224
THR A 225
PRO A 226
HIS A 395
 None
 1.04A 4qknA-5naqA:
undetectable		 4qknA-5naqA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5naq BETA-GALACTOSIDASE
(Lactobacillus
plantarum) 		4 / 7 GLU A   3
PHE A   4
ARG A 458
PHE A 461
 None
 1.23A 4uciB-5naqA:
undetectable		 4uciB-5naqA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HGC_A_HCYA501_1
(SERPIN)		 5naq BETA-GALACTOSIDASE
(Lactobacillus
plantarum) 		5 / 12 PRO A  48
ALA A  51
ARG A  74
GLN A  78
SER A  76
 None
 0.93A 5hgcA-5naqA:
undetectable		 5hgcA-5naqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 5naq BETA-GALACTOSIDASE
(Lactobacillus
plantarum) 		4 / 5 GLN A 384
ASP A 385
SER A 448
ARG A 388
 None
 1.43A 5w4zA-5naqA:
4.6		 5w4zA-5naqA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 5naq BETA-GALACTOSIDASE
(Lactobacillus
plantarum) 		5 / 12 ASP A 104
ILE A  77
ILE A 115
TRP A 160
ARG A 156
 None
 1.48A 6c9zB-5naqA:
4.0		 6c9zB-5naqA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5naq BETA-GALACTOSIDASE
(Lactobacillus
plantarum) 		4 / 8 TRP A 423
HIS A 119
HIS A 299
GLU A 365
 None
 1.22A 6mn4D-5naqA:
undetectable		 6mn4D-5naqA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5naq BETA-GALACTOSIDASE
(Lactobacillus
plantarum) 		4 / 7 TRP A 423
HIS A 119
HIS A 299
GLU A 365
 None
 1.29A 6mn4E-5naqA:
undetectable		 6mn4E-5naqA:
20.08