SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nb3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5nb3 PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum) 		4 / 8 PHE M  28
GLY M  32
LEU M  36
PHE M   5
 None
MPD  M 204 ( 4.0A)
PEB  M 187 (-4.2A)
None
 0.82A 1gsfA-5nb3M:
undetectable		 1gsfA-5nb3M:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5nb3 PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum) 		4 / 8 PHE M  28
GLY M  32
LEU M  36
PHE M   5
 None
MPD  M 204 ( 4.0A)
PEB  M 187 (-4.2A)
None
 0.83A 1gsfB-5nb3M:
undetectable		 1gsfB-5nb3M:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5nb3 PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum) 		4 / 8 PHE M  28
GLY M  32
LEU M  36
PHE M   5
 None
MPD  M 204 ( 4.0A)
PEB  M 187 (-4.2A)
None
 0.83A 1gsfD-5nb3M:
undetectable		 1gsfD-5nb3M:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 5nb3 PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum) 		5 / 9 LEU M 108
ASP M 104
ALA M 100
ASP M  99
VAL M  91
 None
 1.45A 3wsjA-5nb3M:
undetectable		 3wsjA-5nb3M:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 5nb3 PHYCOERYTHRIN ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA SUBUNIT
(Phormidium
rubidum) 		4 / 4 THR A   6
GLY A 103
ASP A 106
SER A   3
 None
 1.24A 4rfqA-5nb3A:
undetectable		 4rfqA-5nb3A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_A_SAMA1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 5nb3 PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum) 		5 / 12 GLY M 119
ASN M  61
CYH M  71
CYH M  80
LEU M  64
 MEN  M  70 ( 4.6A)
None
PEB  M 186 (-3.5A)
PEB  M 186 (-2.0A)
PEB  M 186 ( 4.5A)
 1.34A 5lsuA-5nb3M:
undetectable		 5lsuA-5nb3M:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 5nb3 PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum) 		5 / 10 VAL M  91
LEU M  95
ASP M 104
SER M 174
GLU M 171
 None
 1.24A 5tixB-5nb3M:
undetectable		 5tixB-5nb3M:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5nb3 PHYCOERYTHRIN ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA SUBUNIT
PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum;
Phormidium
rubidum) 		5 / 12 ALA A 159
LEU A 155
SER M   6
VAL A   4
TYR A  89
 None
None
None
None
PEB  A 166 (-4.3A)
 1.07A 6djzC-5nb3A:
undetectable		 6djzC-5nb3A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5nb3 PHYCOERYTHRIN ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA SUBUNIT
(Phormidium
rubidum) 		4 / 5 ALA A  40
TYR A 152
GLN A  94
ILE A  93
 None
PEB  A 167 ( 4.4A)
None
None
 1.26A 6f6sA-5nb3A:
undetectable
6f6sB-5nb3A:
undetectable		 6f6sA-5nb3A:
23.53
6f6sB-5nb3A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5nb3 PHYCOERYTHRIN ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA SUBUNIT
PHYCOERYTHRIN BETA
SUBUNIT,PHYCOERYTHRI
N BETA SUBUNIT
(Phormidium
rubidum;
Phormidium
rubidum) 		5 / 11 TYR M  93
VAL M 102
SER M   6
ALA M   8
VAL A   5
 None
None
None
None
MPD  M 204 (-4.4A)
 1.37A 6hu9A-5nb3M:
undetectable
6hu9E-5nb3M:
undetectable
6hu9I-5nb3M:
undetectable		 6hu9A-5nb3M:
18.50
6hu9E-5nb3M:
22.38
6hu9I-5nb3M:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 5nb3 PHYCOERYTHRIN ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA
SUBUNIT,PHYCOERYTHRI
N ALPHA SUBUNIT
(Phormidium
rubidum) 		4 / 5 GLY A 109
LEU A 105
SER A 162
GLN A 113
 PEB  A 166 ( 4.7A)
None
None
None
 0.90A 6ji6A-5nb3A:
undetectable		 6ji6A-5nb3A:
18.10