SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nbi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 5nbi DESIGN OF ANTIBODIES
(Escherichia
coli) 		3 / 3 TRP L  39
ALA L  54
VAL L  52
 None
 0.90A 1c4dC-5nbiL:
undetectable
1c4dD-5nbiL:
undetectable		 1c4dC-5nbiL:
13.51
1c4dD-5nbiL:
13.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 5nbi DESIGN OF ANTIBODIES
(Escherichia
coli) 		6 / 12 TYR L  40
GLN L  93
PHE L 102
VAL H  37
ALA H  99
TRP H 111
 None
 0.69A 1h8sA-5nbiL:
22.1		 1h8sA-5nbiL:
39.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 5nbi DESIGN OF ANTIBODIES
(Escherichia
coli) 		3 / 3 ALA L  54
VAL L  52
TRP L  39
 None
 0.94A 1w5uA-5nbiL:
undetectable
1w5uB-5nbiL:
undetectable		 1w5uA-5nbiL:
13.51
1w5uB-5nbiL:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5nbi DESIGN OF ANTIBODIES
DESIGN OF ANTIBODIES
(Escherichia
coli;
Escherichia
coli) 		3 / 3 HIS H  31
ASP H 109
ASN L  38
 None
 0.74A 1wg8B-5nbiH:
undetectable		 1wg8B-5nbiH:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5nbi DESIGN OF ANTIBODIES
DESIGN OF ANTIBODIES
(Escherichia
coli;
Escherichia
coli) 		4 / 7 THR L 168
VAL H 171
GLY H 170
THR H 191
 None
 0.96A 2a1mA-5nbiL:
undetectable		 2a1mA-5nbiL:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5nbi DESIGN OF ANTIBODIES
(Escherichia
coli) 		4 / 5 LEU L 183
GLY L 132
PRO L 124
VAL L 136
 None
 0.84A 2aojA-5nbiL:
undetectable		 2aojA-5nbiL:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 5nbi DESIGN OF ANTIBODIES
(Escherichia
coli) 		3 / 3 TRP L  39
ALA L  54
VAL L  52
 None
 0.97A 2izqC-5nbiL:
undetectable
2izqD-5nbiL:
undetectable		 2izqC-5nbiL:
13.51
2izqD-5nbiL:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5nbi DESIGN OF ANTIBODIES
(Escherichia
coli) 		4 / 6 LEU H 197
GLY H 198
ALA H 133
PRO H 134
 None
 0.52A 3huoA-5nbiH:
undetectable		 3huoA-5nbiH:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 5nbi DESIGN OF ANTIBODIES
(Escherichia
coli) 		3 / 3 PHE L  75
TYR L  96
LEU L  51
 None
 0.79A 3keeB-5nbiL:
undetectable		 3keeB-5nbiL:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 5nbi DESIGN OF ANTIBODIES
(Escherichia
coli) 		3 / 3 TRP L  39
ALA L  54
VAL L  52
 None
 0.99A 3l8lC-5nbiL:
undetectable
3l8lD-5nbiL:
undetectable		 3l8lC-5nbiL:
13.51
3l8lD-5nbiL:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 5nbi DESIGN OF ANTIBODIES
(Escherichia
coli) 		4 / 6 ASP L 174
THR L 176
TYR L 144
THR L 113
 None
 1.36A 5b6iB-5nbiL:
undetectable		 5b6iB-5nbiL:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 5nbi DESIGN OF ANTIBODIES
DESIGN OF ANTIBODIES
(Escherichia
coli;
Escherichia
coli) 		5 / 12 ILE H  95
PHE L 102
LYS L  59
VAL L  58
GLY H  44
 None
 1.22A 6a7pA-5nbiH:
undetectable		 6a7pA-5nbiH:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 5nbi DESIGN OF ANTIBODIES
(Escherichia
coli) 		3 / 3 PRO H 193
SER H 195
SER H 196
 None
 0.58A 6bpyA-5nbiH:
undetectable		 6bpyA-5nbiH:
20.78