SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nbo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 5nbo GLYCOSYL HYDROLASE
FAMILY 16
(Bacteroides
ovatus) 		5 / 12 ILE A 265
LEU A  84
ILE A 115
PHE A  41
VAL A  48
 None
 1.10A 2ygnA-5nboA:
undetectable		 2ygnA-5nboA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 5nbo GLYCOSYL HYDROLASE
FAMILY 16
(Bacteroides
ovatus) 		4 / 8 LEU A 255
LEU A 252
VAL A 239
GLY A 122
 None
 0.81A 3dcjB-5nboA:
undetectable		 3dcjB-5nboA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5nbo GLYCOSYL HYDROLASE
FAMILY 16
(Bacteroides
ovatus) 		5 / 12 GLY A 150
GLY A 154
VAL A 164
THR A 120
LEU A 117
 None
 1.03A 3dh0A-5nboA:
undetectable		 3dh0A-5nboA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5nbo GLYCOSYL HYDROLASE
FAMILY 16
(Bacteroides
ovatus) 		5 / 12 GLY A 150
GLY A 154
VAL A 164
THR A 120
LEU A 117
 None
 1.06A 3dh0B-5nboA:
undetectable		 3dh0B-5nboA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_NCAB1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5nbo GLYCOSYL HYDROLASE
FAMILY 16
(Bacteroides
ovatus) 		4 / 7 THR A  59
TRP A  58
ASN A 236
TYR A  66
 None
 1.32A 4a3uB-5nboA:
undetectable		 4a3uB-5nboA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)		 5nbo GLYCOSYL HYDROLASE
FAMILY 16
(Bacteroides
ovatus) 		5 / 12 TYR A 198
LEU A 117
GLU A 148
GLY A 150
GLY A 123
 None
 1.11A 4hfpB-5nboA:
undetectable		 4hfpB-5nboA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 5nbo GLYCOSYL HYDROLASE
FAMILY 16
(Bacteroides
ovatus) 		5 / 12 VAL A  81
ILE A 265
LYS A  51
ILE A  98
PRO A 118
 None
 1.35A 4nnrA-5nboA:
undetectable
4nnrB-5nboA:
undetectable		 4nnrA-5nboA:
18.01
4nnrB-5nboA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 5nbo GLYCOSYL HYDROLASE
FAMILY 16
(Bacteroides
ovatus) 		4 / 6 PHE A 227
GLY A 142
TYR A 226
ALA A 140
 None
 1.25A 4yshB-5nboA:
undetectable		 4yshB-5nboA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 5nbo GLYCOSYL HYDROLASE
FAMILY 16
(Bacteroides
ovatus) 		3 / 3 GLU A  62
TRP A 129
HIS A  54
 None
 0.98A 5xipA-5nboA:
undetectable		 5xipA-5nboA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 5nbo GLYCOSYL HYDROLASE
FAMILY 16
(Bacteroides
ovatus) 		5 / 12 GLY A 122
GLY A 254
VAL A 261
GLN A 191
PRO A 118
 None
 1.01A 6gneA-5nboA:
undetectable		 6gneA-5nboA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 5nbo GLYCOSYL HYDROLASE
FAMILY 16
(Bacteroides
ovatus) 		5 / 12 GLY A 122
GLY A 254
VAL A 261
GLN A 191
PRO A 118
 None
 1.01A 6gneB-5nboA:
undetectable		 6gneB-5nboA:
20.66