SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nbq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 8 PHE G  86
SER G  87
LEU G  88
THR G  74
 None
 0.91A 1sbrA-5nbqG:
undetectable		 1sbrA-5nbqG:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		5 / 12 THR G 101
LEU G 166
ILE G 142
PHE G  96
LEU G  63
 None
 1.27A 1wsvA-5nbqG:
undetectable		 1wsvA-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		5 / 12 THR G 101
LEU G 166
ILE G 142
PHE G  96
LEU G  63
 None
 1.25A 1wsvB-5nbqG:
undetectable		 1wsvB-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 8 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.80A 2eijN-5nbqG:
undetectable
2eijW-5nbqG:
undetectable		 2eijN-5nbqG:
undetectable
2eijW-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 7 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.79A 2eikA-5nbqG:
undetectable
2eikJ-5nbqG:
undetectable		 2eikA-5nbqG:
undetectable
2eikJ-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 8 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.79A 2eikN-5nbqG:
undetectable
2eikW-5nbqG:
undetectable		 2eikN-5nbqG:
undetectable
2eikW-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 8 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.77A 2eilN-5nbqG:
undetectable
2eilW-5nbqG:
undetectable		 2eilN-5nbqG:
undetectable
2eilW-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 8 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.81A 3ablN-5nbqG:
undetectable
3ablW-5nbqG:
undetectable		 3ablN-5nbqG:
undetectable
3ablW-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 8 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.81A 3ag3N-5nbqG:
undetectable
3ag3W-5nbqG:
undetectable		 3ag3N-5nbqG:
undetectable
3ag3W-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 8 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.85A 3asnN-5nbqG:
undetectable
3asnW-5nbqG:
undetectable		 3asnN-5nbqG:
undetectable
3asnW-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 6 ILE G  48
THR G 131
PHE G 106
PHE G  86
 None
 1.31A 3elzB-5nbqG:
2.7		 3elzB-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		5 / 12 THR G  74
PHE G  86
LEU G 166
VAL G  46
PHE G 144
 None
 1.28A 3u9fG-5nbqG:
undetectable
3u9fH-5nbqG:
undetectable		 3u9fG-5nbqG:
undetectable
3u9fH-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		3 / 3 GLU G 117
GLY G 146
SER G 119
 None
 0.66A 4b53B-5nbqG:
undetectable		 4b53B-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 7 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.85A 5b1bN-5nbqG:
undetectable
5b1bW-5nbqG:
undetectable		 5b1bN-5nbqG:
undetectable
5b1bW-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 7 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.86A 5b3sN-5nbqG:
undetectable
5b3sW-5nbqG:
undetectable		 5b3sN-5nbqG:
undetectable
5b3sW-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 7 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.78A 5iy5N-5nbqG:
undetectable
5iy5W-5nbqG:
undetectable		 5iy5N-5nbqG:
undetectable
5iy5W-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 8 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.86A 5xdxN-5nbqG:
undetectable
5xdxW-5nbqG:
undetectable		 5xdxN-5nbqG:
undetectable
5xdxW-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_H_BEZH201_0
(NS3 PROTEASE)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 5 HIS G  81
TYR G 111
GLY G 113
TYR G 159
 None
 1.42A 5yodH-5nbqG:
undetectable		 5yodH-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 8 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.88A 5zcoA-5nbqG:
undetectable
5zcoJ-5nbqG:
undetectable		 5zcoA-5nbqG:
undetectable
5zcoJ-5nbqG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbq OUTER SURFACE
PROTEIN E
(Borreliella
burgdorferi) 		4 / 8 PHE G  86
MET G 100
THR G 101
LEU G 166
 None
 0.86A 5zcqN-5nbqG:
undetectable
5zcqW-5nbqG:
undetectable		 5zcqN-5nbqG:
undetectable
5zcqW-5nbqG:
undetectable