SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nbs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 9 GLU A 624
ARG A 146
ILE A 216
ALA A 247
THR A 220
 None
None
None
NAG  A1109 ( 4.0A)
None
 1.32A 1aj6A-5nbsA:
undetectable		 1aj6A-5nbsA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 11 ALA A 123
LEU A 163
ASP A 113
LEU A 116
GLY A 115
 None
 1.13A 1b02A-5nbsA:
undetectable		 1b02A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 8 GLY A 441
GLY A 447
LEU A  91
GLY A 449
 None
 0.77A 1jhaA-5nbsA:
undetectable		 1jhaA-5nbsA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 ALA A 528
VAL A 533
TRP A 536
 NAG  A1141 ( 3.8A)
None
None
 0.81A 1jo3A-5nbsA:
undetectable		 1jo3A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 ALA A 528
VAL A 533
TRP A 536
 NAG  A1141 ( 3.8A)
None
None
 0.81A 1jo3B-5nbsA:
undetectable		 1jo3B-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_B_MTXB2278_1
(PTERIDINE REDUCTASE
2)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 11 ARG A 517
ASP A 527
LEU A 544
PRO A 549
THR A 592
 None
 1.45A 1mxfB-5nbsA:
4.2		 1mxfB-5nbsA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_C_MTXC3278_1
(PTERIDINE REDUCTASE
2)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 11 ARG A 517
ASP A 527
LEU A 544
PRO A 549
THR A 592
 None
 1.48A 1mxfC-5nbsA:
4.4		 1mxfC-5nbsA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 ALA A 528
VAL A 533
TRP A 536
 NAG  A1141 ( 3.8A)
None
None
 0.93A 1ng8A-5nbsA:
undetectable		 1ng8A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 ALA A 528
VAL A 533
TRP A 536
 NAG  A1141 ( 3.8A)
None
None
 0.93A 1ng8B-5nbsA:
undetectable		 1ng8B-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 ALA A 528
VAL A 533
TRP A 536
 NAG  A1141 ( 3.8A)
None
None
 0.94A 1nruA-5nbsA:
undetectable		 1nruA-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 ALA A 528
VAL A 533
TRP A 536
 NAG  A1141 ( 3.8A)
None
None
 0.94A 1nruB-5nbsA:
undetectable		 1nruB-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 ALA A 169
ALA A 232
LEU A 258
GLY A 165
LEU A 226
 None
None
NAG  A1109 ( 4.8A)
None
None
 1.13A 1qabF-5nbsA:
undetectable		 1qabF-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 ALA A 414
PHE A 412
ALA A 493
ALA A 495
VAL A 499
 None
 1.33A 1rbpA-5nbsA:
undetectable		 1rbpA-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 11 VAL A 530
ASN A 478
GLU A 525
GLU A 418
ILE A 484
 None
None
BMA  A1134 (-3.6A)
None
None
 1.47A 1t6zA-5nbsA:
undetectable		 1t6zA-5nbsA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 8 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.90A 1v54C-5nbsA:
undetectable
1v54J-5nbsA:
undetectable		 1v54C-5nbsA:
undetectable
1v54J-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 MET A 221
LEU A 262
ILE A 233
PHE A 187
ILE A 188
 None
 1.29A 1xotA-5nbsA:
undetectable		 1xotA-5nbsA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YNN_C_RFPC1120_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 ASP A 276
ARG A 196
HIS A 186
ARG A 152
LEU A  91
 None
 1.28A 1ynnC-5nbsA:
undetectable		 1ynnC-5nbsA:
5.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A 591
SER A 589
SER A 649
PHE A 653
 None
 1.17A 2c8aA-5nbsA:
undetectable		 2c8aA-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 ARG A 591
SER A 589
SER A 649
PHE A 653
 None
 1.19A 2c8aC-5nbsA:
undetectable		 2c8aC-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.95A 2eikC-5nbsA:
undetectable
2eikJ-5nbsA:
undetectable		 2eikC-5nbsA:
undetectable
2eikJ-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 8 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.92A 2eikP-5nbsA:
undetectable
2eikW-5nbsA:
undetectable		 2eikP-5nbsA:
undetectable
2eikW-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.87A 2eimP-5nbsA:
undetectable
2eimW-5nbsA:
undetectable		 2eimP-5nbsA:
undetectable
2eimW-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 10 ALA A 495
THR A 494
ALA A 493
ALA A 414
VAL A 497
 None
 0.97A 2f16K-5nbsA:
undetectable
2f16L-5nbsA:
undetectable		 2f16K-5nbsA:
14.42
2f16L-5nbsA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 10 ALA A 495
THR A 494
ALA A 493
ALA A 414
VAL A 497
 None
 0.97A 2f16Y-5nbsA:
undetectable
2f16Z-5nbsA:
undetectable		 2f16Y-5nbsA:
14.42
2f16Z-5nbsA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 PHE A 102
TYR A 453
ARG A 389
GLY A 385
 None
 1.14A 2i30A-5nbsA:
undetectable		 2i30A-5nbsA:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 LEU A 363
ASN A  57
GLN A 347
ILE A 350
 None
NAG  A1101 (-1.8A)
None
None
 1.19A 2jn3A-5nbsA:
undetectable		 2jn3A-5nbsA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 ARG A 332
GLY A 271
PHE A 269
PRO A 752
 None
 1.02A 2m2oB-5nbsA:
undetectable		 2m2oB-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ILE A 391
ARG A 120
PRO A 457
GLY A 441
 None
 1.20A 2pnjB-5nbsA:
undetectable		 2pnjB-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 LEU A 731
PRO A 732
ARG A 325
 MAN  A1126 (-4.4A)
MAN  A1126 (-3.6A)
None
 0.57A 2qd4B-5nbsA:
undetectable		 2qd4B-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 LEU A 731
PRO A 732
ARG A 325
 MAN  A1126 (-4.4A)
MAN  A1126 (-3.6A)
None
 0.60A 2qd5A-5nbsA:
3.2		 2qd5A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 LEU A  52
ALA A 315
GLY A 319
PHE A 684
 None
NAG  A1121 ( 4.0A)
None
None
 0.92A 2wq5A-5nbsA:
undetectable		 2wq5A-5nbsA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 TYR A 244
ARG A 196
GLU A 505
SER A 446
 None
 1.19A 2zt7A-5nbsA:
undetectable		 2zt7A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 1.01A 3abkP-5nbsA:
undetectable
3abkW-5nbsA:
undetectable		 3abkP-5nbsA:
undetectable
3abkW-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.91A 3ag2C-5nbsA:
undetectable		 3ag2C-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.94A 3ag2P-5nbsA:
undetectable
3ag2W-5nbsA:
undetectable		 3ag2P-5nbsA:
undetectable
3ag2W-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 8 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.94A 3ag4C-5nbsA:
undetectable
3ag4J-5nbsA:
undetectable		 3ag4C-5nbsA:
undetectable
3ag4J-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.94A 3ag4P-5nbsA:
undetectable
3ag4W-5nbsA:
undetectable		 3ag4P-5nbsA:
undetectable
3ag4W-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.96A 3asnC-5nbsA:
undetectable
3asnJ-5nbsA:
undetectable		 3asnC-5nbsA:
undetectable
3asnJ-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.97A 3asnP-5nbsA:
undetectable
3asnW-5nbsA:
undetectable		 3asnP-5nbsA:
undetectable
3asnW-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.94A 3asoP-5nbsA:
undetectable
3asoW-5nbsA:
undetectable		 3asoP-5nbsA:
undetectable
3asoW-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAS_A_ASDA332_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 10 THR A 540
SER A 534
VAL A 497
VAL A 542
LEU A 544
 None
 1.48A 3casA-5nbsA:
undetectable		 3casA-5nbsA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 GLY A 504
GLY A 447
GLY A 443
LEU A 137
VAL A  70
 None
 1.05A 3embA-5nbsA:
3.4		 3embA-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 11 ALA A 563
LEU A 407
ILE A 578
LEU A 461
THR A 562
 None
None
None
None
NAG  A1130 ( 4.9A)
 1.25A 3fl9C-5nbsA:
undetectable		 3fl9C-5nbsA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 9 ALA A 563
LEU A 407
ILE A 578
LEU A 461
THR A 562
 None
None
None
None
NAG  A1130 ( 4.9A)
 1.30A 3fl9H-5nbsA:
undetectable		 3fl9H-5nbsA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 VAL A 543
LEU A 454
HIS A 545
GLY A 417
LEU A 476
 None
 1.26A 3j6pB-5nbsA:
undetectable		 3j6pB-5nbsA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 ASN A 450
ASP A 432
ARG A 368
 None
 0.90A 3k13A-5nbsA:
3.3		 3k13A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 ALA A 123
LEU A 163
ASP A 113
LEU A 116
GLY A 115
 None
 1.16A 3k2hB-5nbsA:
undetectable		 3k2hB-5nbsA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 GLY A 138
PHE A 112
PHE A 800
PHE A 157
 None
 1.15A 3ko0L-5nbsA:
undetectable
3ko0N-5nbsA:
undetectable		 3ko0L-5nbsA:
18.81
3ko0N-5nbsA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS201_1
(PROTEIN S100-A4)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 PHE A 157
GLY A 138
PHE A 112
PHE A 800
 None
 1.13A 3ko0K-5nbsA:
undetectable
3ko0S-5nbsA:
undetectable		 3ko0K-5nbsA:
18.81
3ko0S-5nbsA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 PHE A 157
GLY A 138
PHE A 112
PHE A 800
 None
 1.12A 3ko0R-5nbsA:
undetectable
3ko0T-5nbsA:
undetectable		 3ko0R-5nbsA:
18.81
3ko0T-5nbsA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 GLY A 165
ARG A 820
ILE A 166
VAL A 162
 None
 1.15A 3kvvB-5nbsA:
2.6		 3kvvB-5nbsA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 GLY A 165
ARG A 820
ILE A 166
VAL A 162
 None
 1.15A 3kvvE-5nbsA:
undetectable		 3kvvE-5nbsA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 GLY A 165
ARG A 820
ILE A 166
VAL A 162
 None
 1.14A 3kvvF-5nbsA:
undetectable		 3kvvF-5nbsA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 LEU A 399
TRP A 566
GLY A 548
 None
 0.80A 3l35A-5nbsA:
undetectable
3l35H-5nbsA:
undetectable		 3l35A-5nbsA:
undetectable
3l35H-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 LEU A 405
LEU A 565
SER A 577
THR A 107
 None
 0.98A 3lm8B-5nbsA:
undetectable
3lm8D-5nbsA:
2.7		 3lm8B-5nbsA:
16.11
3lm8D-5nbsA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 ASP A 634
ASN A 637
SER A 847
 None
NAG  A1108 (-1.8A)
None
 0.89A 3lslA-5nbsA:
undetectable
3lslD-5nbsA:
undetectable		 3lslA-5nbsA:
undetectable
3lslD-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 SER A 847
ASP A 634
ASN A 637
 None
None
NAG  A1108 (-1.8A)
 0.85A 3lslA-5nbsA:
undetectable
3lslD-5nbsA:
undetectable		 3lslA-5nbsA:
undetectable
3lslD-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 9 VAL A 533
ILE A 496
ALA A 495
ALA A 563
THR A 562
 None
None
None
None
NAG  A1130 ( 4.9A)
 1.12A 3mdvA-5nbsA:
undetectable		 3mdvA-5nbsA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 HIS A 545
VAL A 497
GLY A 571
SER A 574
ALA A 393
 None
 1.02A 3sueC-5nbsA:
undetectable		 3sueC-5nbsA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 LEU A 226
HIS A 222
MET A 221
 None
 0.96A 3thrD-5nbsA:
undetectable		 3thrD-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 LEU A 783
ALA A 767
ASP A 768
VAL A 841
VAL A 843
 None
 1.00A 3ucbA-5nbsA:
undetectable		 3ucbA-5nbsA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.98A 3wg7C-5nbsA:
undetectable
3wg7J-5nbsA:
undetectable		 3wg7C-5nbsA:
undetectable
3wg7J-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.92A 3x2qC-5nbsA:
undetectable
3x2qJ-5nbsA:
undetectable		 3x2qC-5nbsA:
undetectable
3x2qJ-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.92A 3x2qP-5nbsA:
undetectable
3x2qW-5nbsA:
undetectable		 3x2qP-5nbsA:
undetectable
3x2qW-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 GLU A 853
TYR A 842
SER A 786
 None
 0.87A 4at0A-5nbsA:
undetectable		 4at0A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 5 GLY A  61
ILE A 705
VAL A  56
SER A 306
 None
 1.26A 4d33B-5nbsA:
undetectable		 4d33B-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 GLY A 165
ARG A 820
ILE A 166
VAL A 162
 None
 1.12A 4e1vF-5nbsA:
undetectable		 4e1vF-5nbsA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 THR A 159
GLY A 145
PRO A 148
GLY A 604
 None
 0.90A 4fjpA-5nbsA:
undetectable		 4fjpA-5nbsA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 THR A 159
GLY A 145
PRO A 148
GLY A 604
 None
 0.87A 4forA-5nbsA:
undetectable		 4forA-5nbsA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ILE A 172
VAL A 140
PHE A 269
ASP A 276
 None
 1.14A 4iarA-5nbsA:
undetectable		 4iarA-5nbsA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 HIS A 545
GLY A 575
ILE A 578
 None
 0.62A 4k50I-5nbsA:
undetectable		 4k50I-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 ALA A 184
GLY A 105
PHE A 157
GLY A 142
THR A 171
 None
 1.21A 4mm8A-5nbsA:
undetectable		 4mm8A-5nbsA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 ARG A 820
ASP A 821
ARG A 234
 None
 0.90A 4mx0A-5nbsA:
undetectable		 4mx0A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 GLY A 438
GLY A 421
ASN A 437
ILE A 442
THR A 448
 None
None
NAG  A1129 (-1.9A)
None
None
 1.13A 4n48A-5nbsA:
3.0		 4n48A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 GLY A 438
GLY A 421
ASN A 437
ILE A 442
THR A 448
 None
None
NAG  A1129 (-1.9A)
None
None
 1.09A 4n48B-5nbsA:
2.7		 4n48B-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 4 ALA A 330
VAL A  56
GLY A  61
THR A  73
 None
 1.13A 4ubeA-5nbsA:
4.5		 4ubeA-5nbsA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.93A 5b1bP-5nbsA:
undetectable
5b1bW-5nbsA:
undetectable		 5b1bP-5nbsA:
undetectable
5b1bW-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 TYR A 244
GLY A 506
GLU A 505
ASP A 432
 None
 1.25A 5emlA-5nbsA:
3.0		 5emlA-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 TYR A 225
ILE A 628
GLY A 789
PRO A 790
LEU A 144
 None
 1.19A 5ienA-5nbsA:
undetectable		 5ienA-5nbsA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 GLY A 515
LEU A  91
GLY A 445
SER A 446
PRO A  90
 None
 1.45A 5jglB-5nbsA:
2.6		 5jglB-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 ILE A 564
VAL A 530
VAL A 542
TRP A 555
 None
 0.97A 5jwaH-5nbsA:
undetectable		 5jwaH-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 5 SER A 639
VAL A 640
GLY A 597
ALA A 598
 None
 1.04A 5k50A-5nbsA:
undetectable		 5k50A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		6 / 12 ASP A  88
ARG A 152
LYS A 185
HIS A 186
MET A 241
GLU A 505
 None
 0.47A 5m6gA-5nbsA:
32.9		 5m6gA-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 GLU A 345
PHE A 337
THR A  73
GLY A  80
LEU A  81
 None
 1.23A 5ogcB-5nbsA:
4.2		 5ogcB-5nbsA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 5 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.96A 5x19C-5nbsA:
undetectable
5x19J-5nbsA:
undetectable		 5x19C-5nbsA:
undetectable
5x19J-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 6 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.96A 5x19P-5nbsA:
undetectable		 5x19P-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 5 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.92A 5x1bP-5nbsA:
undetectable		 5x1bP-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.94A 5x1fP-5nbsA:
undetectable
5x1fW-5nbsA:
undetectable		 5x1fP-5nbsA:
undetectable
5x1fW-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 5 PRO A 422
GLY A 438
THR A 439
ASN A 423
 None
 1.22A 5x23A-5nbsA:
undetectable		 5x23A-5nbsA:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.97A 5zcqC-5nbsA:
undetectable
5zcqJ-5nbsA:
undetectable		 5zcqC-5nbsA:
undetectable
5zcqJ-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 7 ARG A  78
LEU A  79
PHE A  46
LEU A  50
 None
 0.95A 5zcqP-5nbsA:
undetectable
5zcqW-5nbsA:
undetectable		 5zcqP-5nbsA:
undetectable
5zcqW-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		4 / 5 ASN A 379
VAL A 133
LEU A 136
SER A 100
 None
 1.15A 6a7pA-5nbsA:
undetectable		 6a7pA-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 VAL A 640
VAL A 106
PHE A 633
PRO A 148
PHE A 594
 None
 1.48A 6becA-5nbsA:
undetectable
6becB-5nbsA:
undetectable
6becC-5nbsA:
undetectable		 6becA-5nbsA:
7.61
6becB-5nbsA:
7.61
6becC-5nbsA:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 12 HIS A 545
VAL A 497
GLY A 571
SER A 574
ALA A 393
 None
 1.03A 6c2mC-5nbsA:
undetectable		 6c2mC-5nbsA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		3 / 3 PHE A 269
ARG A 332
ALA A  33
 None
 0.95A 6ecfB-5nbsA:
3.1		 6ecfB-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5nbs BETA-GLUCOSIDASE
(Neurospora
crassa) 		5 / 10 MET A 300
SER A 303
GLY A 304
GLY A  63
LEU A 263
 None
NAG  A1118 ( 4.8A)
None
None
None
 1.31A 6hqbA-5nbsA:
undetectable
6hqbJ-5nbsA:
undetectable		 6hqbA-5nbsA:
19.61
6hqbJ-5nbsA:
23.08