SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nd1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 4 HIS A 115
LEU A 234
LEU A 342
LEU A 349
 None
 0.99A 1a4lD-5nd1A:
undetectable		 1a4lD-5nd1A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 LEU B 329
TYR B 327
HIS B 220
THR B 230
 None
 1.25A 1afsA-5nd1B:
undetectable		 1afsA-5nd1B:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 LEU B 580
HIS B 437
THR B 570
ASN B 490
 None
 0.90A 1afsA-5nd1B:
undetectable		 1afsA-5nd1B:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 LEU B 329
TYR B 327
HIS B 220
THR B 230
 None
 1.25A 1afsB-5nd1B:
undetectable		 1afsB-5nd1B:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 LEU B 580
HIS B 437
THR B 570
ASN B 490
 None
 0.89A 1afsB-5nd1B:
undetectable		 1afsB-5nd1B:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 5nd1 CAPSID PROTEIN
CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1;
Rosellinia
necatrix
quadrivirus
1) 		3 / 3 VAL B 904
VAL A 893
TRP B 906
 None
 0.90A 1av2C-5nd1B:
undetectable
1av2D-5nd1B:
undetectable		 1av2C-5nd1B:
undetectable
1av2D-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 THR B 514
THR B 629
GLY B 646
ASP B 644
 None
 0.90A 1bu5A-5nd1B:
undetectable		 1bu5A-5nd1B:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 THR B 514
THR B 629
GLY B 646
ASP B 644
 None
 0.91A 1bu5B-5nd1B:
undetectable		 1bu5B-5nd1B:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 9 ALA B 828
HIS B 872
THR B 868
GLY B 148
THR B 126
 None
 1.21A 1c9sQ-5nd1B:
undetectable
1c9sR-5nd1B:
undetectable		 1c9sQ-5nd1B:
undetectable
1c9sR-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 SER A  61
HIS A 862
LEU A 608
MET A 528
LEU A  66
 None
 1.47A 1fm6D-5nd1A:
undetectable		 1fm6D-5nd1A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 9 GLY B 148
THR B 126
ALA B 828
HIS B 872
THR B 868
 None
 1.20A 1gtfD-5nd1B:
undetectable
1gtfE-5nd1B:
undetectable		 1gtfD-5nd1B:
undetectable
1gtfE-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 ASP B 215
PHE B 178
VAL B 212
 None
 0.68A 1kijB-5nd1B:
undetectable		 1kijB-5nd1B:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 PHE A 590
ILE A 461
GLY A 462
GLY A 526
THR A 522
 None
 1.06A 1nv8A-5nd1A:
undetectable		 1nv8A-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 PHE A 590
ILE A 461
GLY A 462
GLY A 526
THR A 522
 None
 1.05A 1nv8B-5nd1A:
undetectable		 1nv8B-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 GLY B 275
GLN B 277
TRP B 273
SER B 280
 None
 1.29A 1p6kB-5nd1B:
undetectable		 1p6kB-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 5nd1 CAPSID PROTEIN
CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1;
Rosellinia
necatrix
quadrivirus
1) 		5 / 11 GLY B 188
GLY A 513
TYR A 441
HIS A 455
LEU A 611
 None
 1.13A 1p91A-5nd1B:
undetectable		 1p91A-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 VAL B 554
ASP A 872
HIS B 437
LEU B 157
 None
 1.13A 1pk2A-5nd1B:
undetectable		 1pk2A-5nd1B:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 PHE B 479
LEU B 483
PHE B 423
VAL B 232
VAL B 554
 None
 1.19A 1q23H-5nd1B:
undetectable
1q23I-5nd1B:
undetectable		 1q23H-5nd1B:
16.67
1q23I-5nd1B:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RR8_A_TTCA100_1
(DNA TOPOISOMERASE I)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 ARG B 765
LYS B 349
ASP B 317
THR B 321
 None
 1.47A 1rr8C-5nd1B:
undetectable		 1rr8C-5nd1B:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 GLY B 275
GLN B 277
TRP B 273
SER B 280
 None
 1.29A 1rs6B-5nd1B:
undetectable		 1rs6B-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 5nd1 CAPSID PROTEIN
CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1;
Rosellinia
necatrix
quadrivirus
1) 		5 / 12 ALA B 189
GLY B 188
GLY B 187
ASP B 991
GLY A 505
 None
 0.79A 1sqfA-5nd1B:
undetectable		 1sqfA-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 6 LEU A 608
ALA A 524
LEU A  49
THR A 520
 None
 1.18A 1tyrA-5nd1A:
undetectable		 1tyrA-5nd1A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 ALA A 466
ALA A 457
PHE A 193
LEU A 487
PHE A 483
 None
 1.08A 1uduB-5nd1A:
undetectable		 1uduB-5nd1A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 5nd1 CAPSID PROTEIN
CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1;
Rosellinia
necatrix
quadrivirus
1) 		3 / 3 VAL B 904
VAL A 893
TRP B 906
 None
 0.85A 1w5uC-5nd1B:
undetectable
1w5uD-5nd1B:
undetectable		 1w5uC-5nd1B:
undetectable
1w5uD-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 PHE A 400
PHE A 193
MET A 201
SER A 204
 None
 0.89A 1wrlE-5nd1A:
undetectable		 1wrlE-5nd1A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 THR A 786
LEU A 822
ILE A 787
CYH A 820
LEU A 846
 None
 1.23A 1wsvB-5nd1A:
undetectable		 1wsvB-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 PHE A 563
ALA A 588
HIS A 583
LEU A 571
 None
 1.06A 1x8vA-5nd1A:
undetectable		 1x8vA-5nd1A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 GLY B 873
GLY B 874
LEU B 891
SER B 892
LEU B 866
 None
 1.12A 1ya4B-5nd1B:
undetectable		 1ya4B-5nd1B:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 LEU A  65
LEU A  51
LEU A  49
LEU A  60
 None
 0.95A 1yajD-5nd1A:
undetectable		 1yajD-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 TRP A 105
LEU A 473
LYS A 240
 None
 1.18A 1yajK-5nd1A:
undetectable		 1yajK-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 GLY B 275
GLN B 277
TRP B 273
SER B 280
 None
 1.31A 1zzuB-5nd1B:
undetectable		 1zzuB-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 THR B 264
PRO B 265
GLY B 895
ASP B 896
 None
 0.93A 2ddwB-5nd1B:
undetectable		 2ddwB-5nd1B:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 THR B 264
PRO B 265
HIS B 266
GLY B 895
 None
 0.87A 2ddwB-5nd1B:
undetectable		 2ddwB-5nd1B:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 VAL A 631
ARG A 728
LEU A 253
THR A 730
 None
 1.06A 2f78A-5nd1A:
undetectable		 2f78A-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 6 SER A 394
GLY A 401
THR A 403
ARG A 198
 None
 1.17A 2f7fA-5nd1A:
undetectable		 2f7fA-5nd1A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 5nd1 CAPSID PROTEIN
CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1;
Rosellinia
necatrix
quadrivirus
1) 		3 / 3 VAL A 893
TRP B 906
VAL B 904
 None
 0.83A 2izqA-5nd1A:
undetectable
2izqB-5nd1A:
undetectable		 2izqA-5nd1A:
undetectable
2izqB-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 ARG A 445
VAL A 495
THR A 129
 None
 0.73A 2nmzA-5nd1A:
undetectable		 2nmzA-5nd1A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 ALA A 779
ALA A 761
ALA A 763
ILE A 787
LEU A 846
 None
 1.18A 2nyrA-5nd1A:
undetectable		 2nyrA-5nd1A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 LEU A 106
VAL A 108
ILE A 860
ALA A 527
LEU A  55
 None
 1.03A 2q72A-5nd1A:
undetectable		 2q72A-5nd1A:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 LEU A 106
VAL A 108
ILE A 860
ALA A 527
LEU A  55
 None
 1.04A 2qb4A-5nd1A:
0.0		 2qb4A-5nd1A:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 GLY A 778
ALA A 779
ILE A 787
ALA A 809
ILE A 805
 None
 0.89A 2rkfA-5nd1A:
undetectable		 2rkfA-5nd1A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5nd1 CAPSID PROTEIN
CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1;
Rosellinia
necatrix
quadrivirus
1) 		4 / 8 VAL B 551
PRO B 552
THR B 530
ARG A 833
 None
 0.80A 2v32C-5nd1B:
undetectable
2v32D-5nd1B:
undetectable		 2v32C-5nd1B:
undetectable
2v32D-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 ASN A 203
SER A 204
TYR A 523
PHE A 400
 None
 1.27A 2wekA-5nd1A:
undetectable		 2wekA-5nd1A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 ASN A 203
SER A 204
TYR A 523
PHE A 400
 None
 1.24A 2wekB-5nd1A:
undetectable		 2wekB-5nd1A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 VAL B 363
ASN B 555
VAL B 554
GLY B 579
ALA B 439
 None
 1.12A 2x2iA-5nd1B:
undetectable		 2x2iA-5nd1B:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 ILE B 689
VAL B 259
GLN B 518
ARG B 424
TYR B 656
 None
 1.17A 2ziaB-5nd1B:
undetectable		 2ziaB-5nd1B:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 GLN A 467
THR A 468
THR A 520
LEU A 608
 None
 0.97A 2zj0A-5nd1A:
undetectable		 2zj0A-5nd1A:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 6 GLY B 641
ILE B 813
GLU B 638
ILE B 633
 None
 0.97A 3a7eA-5nd1B:
undetectable		 3a7eA-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 GLN B 482
PHE B 479
LEU B 950
PHE B 118
 None
 1.27A 3ablC-5nd1B:
undetectable
3ablJ-5nd1B:
undetectable		 3ablC-5nd1B:
undetectable
3ablJ-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 GLN B 184
LEU B 199
ALA B 189
CYH A 380
LEU A 377
 None
 1.26A 3b0wA-5nd1B:
undetectable		 3b0wA-5nd1B:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 GLN B 184
LEU B 199
PHE A 431
CYH A 380
LEU A 377
 None
 1.27A 3b0wA-5nd1B:
undetectable		 3b0wA-5nd1B:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 LEU B 154
ALA B 105
GLY B 819
THR B 494
ILE B 487
 None
 0.98A 3c6gA-5nd1B:
undetectable		 3c6gA-5nd1B:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 GLN A 467
THR A 468
THR A 520
LEU A 608
 None
 0.95A 3ce6A-5nd1A:
undetectable		 3ce6A-5nd1A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 GLN A 467
THR A 468
THR A 520
LEU A 608
 None
 0.94A 3ce6C-5nd1A:
undetectable		 3ce6C-5nd1A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 VAL B 815
ALA B 640
ALA B 624
THR B 821
ILE B 889
 None
 1.30A 3dl9B-5nd1B:
undetectable		 3dl9B-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 GLY B 438
ALA B 581
ASP A 872
VAL A 870
ILE B 689
 None
 1.09A 3ebzB-5nd1B:
undetectable		 3ebzB-5nd1B:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 THR A 468
ASN A 859
LEU A  55
THR A  52
LEU A  75
 None
 1.26A 3fsuA-5nd1A:
undetectable		 3fsuA-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 ARG A 833
GLU A  79
ASP A 857
 None
 0.91A 3g2oA-5nd1A:
undetectable		 3g2oA-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 10 GLN B 485
LEU B 397
VAL B 232
VAL B 228
LEU B 401
 None
 1.01A 3gwxA-5nd1B:
undetectable		 3gwxA-5nd1B:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 THR A  82
THR A  84
ILE A 760
MET A 810
LEU A 777
 None
 1.17A 3gwxA-5nd1A:
undetectable		 3gwxA-5nd1A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 MET A 812
CYH A 664
PRO A 806
 None
 0.80A 3h52C-5nd1A:
undetectable		 3h52C-5nd1A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_PNTA901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 TYR B 612
TRP B 876
GLY B 890
SER B 867
ASN B 909
 None
 1.28A 3hiiA-5nd1B:
undetectable		 3hiiA-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_PNTB901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 TYR B 612
TRP B 876
GLY B 890
SER B 867
ASN B 909
 None
 1.26A 3hiiB-5nd1B:
undetectable		 3hiiB-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 LYS A 334
PRO A 306
SER A 308
LEU A 273
 None
 1.49A 3ijxH-5nd1A:
undetectable		 3ijxH-5nd1A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 10 THR B 596
TYR B 589
VAL B 643
GLY B 646
GLY B 645
 None
 1.35A 3ixlA-5nd1B:
undetectable		 3ixlA-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 GLU B 155
GLY B 817
ARG B 424
ASP B 272
GLY B 586
 None
 1.22A 3jzjA-5nd1B:
undetectable		 3jzjA-5nd1B:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 GLU A 740
LEU A 478
ASP A 472
ARG A 627
ARG A 471
 None
 1.49A 3k39B-5nd1A:
undetectable		 3k39B-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 GLU A 740
LEU A 478
ASP A 472
ARG A 627
ARG A 471
 None
 1.49A 3k39C-5nd1A:
undetectable		 3k39C-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 GLU A 740
LEU A 478
ASP A 472
ARG A 627
ARG A 471
 None
 1.48A 3k39J-5nd1A:
undetectable		 3k39J-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 GLU A 740
LEU A 478
ASP A 472
ARG A 627
ARG A 471
 None
 1.49A 3k39K-5nd1A:
undetectable		 3k39K-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 GLU A 740
LEU A 478
ASP A 472
ARG A 627
ARG A 471
 None
 1.49A 3k39L-5nd1A:
undetectable		 3k39L-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 4 ARG B 390
ASP B 256
GLY A 951
THR B 112
 None
 1.41A 3k4vB-5nd1B:
undetectable		 3k4vB-5nd1B:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 ARG A 445
VAL A 495
THR A 129
 None
 0.82A 3k4vD-5nd1A:
undetectable		 3k4vD-5nd1A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 5nd1 CAPSID PROTEIN
CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1;
Rosellinia
necatrix
quadrivirus
1) 		3 / 3 ASN A 939
ASN A 937
GLU B 916
 None
 0.88A 3kpdC-5nd1A:
undetectable		 3kpdC-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5nd1 CAPSID PROTEIN
CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1;
Rosellinia
necatrix
quadrivirus
1) 		3 / 3 ASN A 939
ASN A 937
GLU B 916
 None
 0.73A 3kpdB-5nd1A:
undetectable		 3kpdB-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 5nd1 CAPSID PROTEIN
CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1;
Rosellinia
necatrix
quadrivirus
1) 		3 / 3 VAL B 904
VAL A 893
TRP B 906
 None
 0.85A 3l8lC-5nd1B:
undetectable
3l8lD-5nd1B:
undetectable		 3l8lC-5nd1B:
undetectable
3l8lD-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 GLU A 220
GLU B 322
ASN B 323
 None
 0.79A 3lp9B-5nd1A:
undetectable
3lp9D-5nd1A:
undetectable		 3lp9B-5nd1A:
14.29
3lp9D-5nd1A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 6 ILE B 487
ALA B 420
ALA B 558
THR B 494
 None
 1.02A 3mdrB-5nd1B:
undetectable		 3mdrB-5nd1B:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 TYR B 327
MET B 404
LEU B 401
LEU B 329
 None
 1.28A 3nk2X-5nd1B:
undetectable		 3nk2X-5nd1B:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 9 ALA B 925
ASP B 928
ILE B 927
GLY B 131
ILE B 129
 None
 1.06A 3nu4A-5nd1B:
undetectable		 3nu4A-5nd1B:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 LEU A 623
ASP A 254
ALA A 251
SER A 628
 None
 1.11A 3rodA-5nd1A:
undetectable		 3rodA-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 9 ALA B 181
PHE B 178
ASN B 323
ARG B 211
GLU B 213
 None
 1.32A 3rukC-5nd1B:
0.0		 3rukC-5nd1B:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 4 LEU A 396
GLY A 398
GLY A 401
THR A 403
 None
 0.88A 3si7A-5nd1A:
undetectable		 3si7A-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 GLN A 496
PHE A 191
TYR A 447
 None
 0.79A 3ucjB-5nd1A:
undetectable		 3ucjB-5nd1A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 GLN A 496
PHE A 191
TYR A 447
 None
 0.79A 3ucjA-5nd1A:
undetectable		 3ucjA-5nd1A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 LEU B 901
THR B 494
ILE B 498
TYR B 499
PHE B 824
 None
 1.16A 3vw1D-5nd1B:
undetectable		 3vw1D-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 LEU A 170
ARG A 174
TYR A 411
GLU A 408
 None
 1.45A 3zmdA-5nd1A:
undetectable
3zmdB-5nd1A:
undetectable		 3zmdA-5nd1A:
19.44
3zmdB-5nd1A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 TRP A 309
VAL A 281
TRP A 333
 None
 1.49A 3zq8A-5nd1A:
undetectable
3zq8B-5nd1A:
undetectable		 3zq8A-5nd1A:
undetectable
3zq8B-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 9 GLY B 808
PHE B 588
THR B 514
GLY B 586
ARG B 424
 None
 1.34A 4acaB-5nd1B:
undetectable
4acaC-5nd1B:
undetectable		 4acaB-5nd1B:
undetectable
4acaC-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		6 / 12 LEU B 894
ILE B 893
ASN B 885
GLY B 814
VAL B 815
GLY A 920
 None
 1.21A 4an2A-5nd1B:
undetectable		 4an2A-5nd1B:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 10 GLY B 628
ALA B 810
GLY B 645
VAL B 599
HIS B 431
 None
 1.40A 4c5nD-5nd1B:
undetectable		 4c5nD-5nd1B:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 6 LEU A 608
ALA A 524
LEU A  49
THR A 520
 None
 1.15A 4d7bB-5nd1A:
undetectable		 4d7bB-5nd1A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 ILE A 787
ALA A 775
GLY A 774
GLY A 782
HIS A 800
 None
 1.29A 4e47A-5nd1A:
undetectable		 4e47A-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 ILE A 787
ALA A 775
GLY A 774
GLY A 782
HIS A 800
 None
 1.29A 4e47C-5nd1A:
undetectable		 4e47C-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 9 VAL A 703
VAL A 283
ILE A 285
GLY A 287
ALA A 293
 None
 1.08A 4fwdA-5nd1A:
undetectable		 4fwdA-5nd1A:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 GLY B 374
ILE B 372
ASN B 449
GLU B 322
 None
 0.98A 4g0vA-5nd1B:
undetectable		 4g0vA-5nd1B:
7.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 LEU B 235
PHE B 388
VAL B 394
SER B 365
GLY B 370
 None
 1.34A 4hvcB-5nd1B:
undetectable		 4hvcB-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 ILE A 787
ALA A 775
GLY A 774
GLY A 782
HIS A 800
 None
 1.29A 4jdsC-5nd1A:
undetectable		 4jdsC-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 ILE A 787
ALA A 775
GLY A 774
GLY A 782
HIS A 800
 None
 1.28A 4jlgA-5nd1A:
undetectable		 4jlgA-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 SER A 729
GLU A 688
VAL A 558
THR A 557
 None
 0.92A 4lnwA-5nd1A:
undetectable		 4lnwA-5nd1A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 6 SER A 729
GLU A 688
VAL A 558
THR A 557
 None
 0.97A 4lnxA-5nd1A:
undetectable		 4lnxA-5nd1A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 HIS B 686
TRP B 273
SER B 684
 None
 0.93A 4lrhD-5nd1B:
undetectable		 4lrhD-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 THR B 373
THR B 378
GLY B 370
ALA B 342
THR B 346
 None
 1.33A 4qvlV-5nd1B:
undetectable
4qvlb-5nd1B:
undetectable		 4qvlV-5nd1B:
18.14
4qvlb-5nd1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 THR B 373
THR B 378
GLY B 370
ALA B 342
THR B 346
 None
 1.34A 4qvlH-5nd1B:
undetectable
4qvlN-5nd1B:
undetectable		 4qvlH-5nd1B:
18.14
4qvlN-5nd1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 THR B 373
THR B 378
GLY B 370
ALA B 342
THR B 346
 None
 1.34A 4qvmV-5nd1B:
undetectable
4qvmb-5nd1B:
undetectable		 4qvmV-5nd1B:
18.14
4qvmb-5nd1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 THR B 373
THR B 378
GLY B 370
ALA B 342
THR B 346
 None
 1.34A 4qvmH-5nd1B:
undetectable
4qvmN-5nd1B:
undetectable		 4qvmH-5nd1B:
18.14
4qvmN-5nd1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 THR B 373
THR B 378
GLY B 370
ALA B 342
THR B 346
 None
 1.35A 4qvwV-5nd1B:
undetectable
4qvwb-5nd1B:
undetectable		 4qvwV-5nd1B:
18.14
4qvwb-5nd1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 THR B 373
THR B 378
GLY B 370
ALA B 342
THR B 346
 None
 1.35A 4qvwH-5nd1B:
undetectable
4qvwN-5nd1B:
undetectable		 4qvwH-5nd1B:
18.14
4qvwN-5nd1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 THR B 373
THR B 378
GLY B 370
ALA B 342
THR B 346
 None
 1.34A 4qw0V-5nd1B:
undetectable
4qw0b-5nd1B:
undetectable		 4qw0V-5nd1B:
18.14
4qw0b-5nd1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 THR B 373
THR B 378
GLY B 370
ALA B 342
THR B 346
 None
 1.34A 4qw0H-5nd1B:
undetectable
4qw0N-5nd1B:
undetectable		 4qw0H-5nd1B:
18.14
4qw0N-5nd1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 THR B 373
THR B 378
GLY B 370
ALA B 342
THR B 346
 None
 1.34A 4qw3V-5nd1B:
undetectable
4qw3b-5nd1B:
undetectable		 4qw3V-5nd1B:
18.14
4qw3b-5nd1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 THR B 373
THR B 378
GLY B 370
ALA B 342
THR B 346
 None
 1.35A 4qw3H-5nd1B:
undetectable
4qw3N-5nd1B:
undetectable		 4qw3H-5nd1B:
18.14
4qw3N-5nd1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 ALA B 925
GLY B 131
ALA B 130
GLU B 140
 None
 0.89A 4r1zB-5nd1B:
undetectable		 4r1zB-5nd1B:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 9 ALA B 439
ILE B 487
THR B 225
ILE B 159
VAL B 232
 None
 1.06A 4r21B-5nd1B:
undetectable		 4r21B-5nd1B:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 GLU A 361
ILE B 998
ALA A 358
 None
 0.53A 4wnwB-5nd1A:
undetectable		 4wnwB-5nd1A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 GLY A 391
GLN A 413
ASN A 387
HIS A 392
 None
 1.08A 4ws0A-5nd1A:
undetectable		 4ws0A-5nd1A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 ASP A 227
LEU A 316
GLY A 315
 None
 0.52A 4xmfA-5nd1A:
undetectable		 4xmfA-5nd1A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 PHE A 390
VAL A 265
GLY A 327
VAL A 288
SER A 394
 None
 0.82A 4xnxA-5nd1A:
undetectable		 4xnxA-5nd1A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 10 ALA A 524
LEU A 519
LEU A  65
SER A  61
LEU A  60
 None
 1.06A 4zbrA-5nd1A:
undetectable		 4zbrA-5nd1A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 4 VAL A 870
ALA A 871
ASN A 660
GLN A 659
 None
 1.34A 4zgfA-5nd1A:
undetectable		 4zgfA-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 GLY B 163
LEU B 360
LEU B 157
LEU B 422
PHE B 578
 None
 1.08A 4zmeA-5nd1B:
undetectable		 4zmeA-5nd1B:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 GLU B 638
THR B 635
HIS B 818
LEU B 894
 None
 1.29A 5axaA-5nd1B:
undetectable		 5axaA-5nd1B:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 GLU B 638
THR B 635
HIS B 818
LEU B 894
 None
 1.31A 5axaC-5nd1B:
undetectable		 5axaC-5nd1B:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 THR B 373
THR B 378
GLY B 370
ALA B 342
THR B 346
 None
 1.33A 5d0xV-5nd1B:
undetectable
5d0xb-5nd1B:
undetectable		 5d0xV-5nd1B:
18.14
5d0xb-5nd1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 THR B 373
THR B 378
GLY B 370
ALA B 342
THR B 346
 None
 1.33A 5d0xH-5nd1B:
undetectable
5d0xN-5nd1B:
undetectable		 5d0xH-5nd1B:
18.14
5d0xN-5nd1B:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 ALA B 258
LEU B 950
PHE B 118
GLY B 476
PHE B 423
 None
 1.15A 5fsaA-5nd1B:
undetectable		 5fsaA-5nd1B:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 7 LEU A 234
ILE A 344
LEU A 230
MET A 201
 None
 1.06A 5fxtA-5nd1A:
undetectable		 5fxtA-5nd1A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 5nd1 CAPSID PROTEIN
CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1;
Rosellinia
necatrix
quadrivirus
1) 		4 / 5 GLY B 646
PRO A 924
THR B 629
THR B 596
 None
 1.23A 5h5fA-5nd1B:
undetectable		 5h5fA-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 HIS B 686
VAL B 259
GLY B 354
ALA B 355
 None
 0.87A 5hwaA-5nd1B:
undetectable		 5hwaA-5nd1B:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 TYR A 888
TYR B 499
GLN B 500
 None
 0.99A 5jsdA-5nd1A:
undetectable
5jsdB-5nd1A:
undetectable		 5jsdA-5nd1A:
7.50
5jsdB-5nd1A:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 TYR A 888
TYR B 499
GLN B 500
 None
 1.00A 5jsdB-5nd1A:
undetectable
5jsdC-5nd1A:
undetectable		 5jsdB-5nd1A:
7.50
5jsdC-5nd1A:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		6 / 12 GLY B 873
ARG B 298
GLY B 297
THR B 898
GLY B 897
GLY B 890
 None
 1.44A 5koxA-5nd1B:
undetectable		 5koxA-5nd1B:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 6 LEU A 608
ALA A 524
LEU A  49
THR A 520
 None
 1.20A 5l4iB-5nd1A:
undetectable		 5l4iB-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 HIS A 238
SER A 477
HIS A 107
VAL A 340
 None
 0.99A 5m8rB-5nd1A:
undetectable		 5m8rB-5nd1A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 HIS A 238
SER A 477
HIS A 107
VAL A 340
 None
 0.92A 5m8rD-5nd1A:
undetectable		 5m8rD-5nd1A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 GLY B 356
HIS B 357
PHE B 118
PHE B 423
ALA B 439
 None
 1.18A 5n0rA-5nd1B:
undetectable		 5n0rA-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 6 LEU A 478
SER A 629
ARG A 728
GLY A 476
 None
 1.10A 5o4yF-5nd1A:
undetectable		 5o4yF-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 GLY B 148
THR B 125
ASN B 123
 None
 0.70A 5odiG-5nd1B:
undetectable		 5odiG-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 4 HIS B 403
HIS B 220
TYR B 327
GLU B 450
 None
 1.18A 5pahA-5nd1B:
undetectable		 5pahA-5nd1B:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 CYH A 135
MET A 148
ASN A 151
 None
 0.92A 5qh8A-5nd1A:
undetectable		 5qh8A-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 LEU A 377
ALA A 381
LEU A 384
LEU A 419
 None
 0.72A 5vkqA-5nd1A:
undetectable
5vkqD-5nd1A:
undetectable		 5vkqA-5nd1A:
undetectable
5vkqD-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 LEU A 419
LEU A 377
ALA A 381
LEU A 384
 None
 0.72A 5vkqA-5nd1A:
undetectable
5vkqB-5nd1A:
undetectable		 5vkqA-5nd1A:
undetectable
5vkqB-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 LEU A 419
LEU A 377
ALA A 381
LEU A 384
 None
 0.69A 5vkqB-5nd1A:
undetectable
5vkqC-5nd1A:
undetectable		 5vkqB-5nd1A:
undetectable
5vkqC-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 LEU A 419
LEU A 377
ALA A 381
LEU A 384
 None
 0.75A 5vkqC-5nd1A:
undetectable
5vkqD-5nd1A:
undetectable		 5vkqC-5nd1A:
undetectable
5vkqD-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 GLN B 787
ILE B 689
GLN B 518
ASP B 272
 None
 0.98A 5vlmH-5nd1B:
undetectable		 5vlmH-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 GLY B 691
GLN B 518
ASP B 585
ASP B 688
 None
 0.96A 5vlmH-5nd1B:
undetectable		 5vlmH-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 GLY B 275
GLN B 277
TRP B 273
SER B 280
 None
 1.34A 5vunA-5nd1B:
undetectable		 5vunA-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_B_HFGB1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 GLU B 693
VAL B 695
THR B 657
GLU B 650
HIS B 805
 None
 1.34A 5xipB-5nd1B:
undetectable		 5xipB-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 ALA A 113
GLY A 398
ASP A 254
ALA A 250
PRO A 482
 None
 1.16A 5zvgA-5nd1A:
undetectable		 5zvgA-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 ALA A 113
GLY A 398
ASP A 254
ALA A 250
PRO A 482
 None
 1.17A 5zvgB-5nd1A:
undetectable		 5zvgB-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 LEU A 346
LEU A 230
PRO A 397
GLY A 401
LEU A 396
 None
 1.01A 6b0iB-5nd1A:
undetectable		 6b0iB-5nd1A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 LEU A 346
LEU A 230
PRO A 397
GLY A 401
LEU A 396
 None
 1.11A 6b0lB-5nd1A:
undetectable		 6b0lB-5nd1A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 VAL A 465
LEU A 346
LEU A 230
GLY A 401
LEU A 396
 None
 1.18A 6b0lB-5nd1A:
undetectable		 6b0lB-5nd1A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 PHE B 824
LEU B 120
VAL B 857
CYH B 827
ILE B 101
 None
 1.25A 6bxmA-5nd1B:
undetectable		 6bxmA-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 PHE B 824
LEU B 120
VAL B 857
CYH B 827
ILE B 101
 None
 1.25A 6bxnA-5nd1B:
undetectable		 6bxnA-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 12 PHE B 824
LEU B 120
VAL B 857
CYH B 827
ILE B 101
 None
 1.24A 6bxnB-5nd1B:
undetectable		 6bxnB-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 ARG B 481
LYS B 106
ARG B 835
 None
 1.36A 6c06D-5nd1B:
undetectable		 6c06D-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 TRP B 234
THR B 230
TRP B 250
LEU B 393
 None
 1.08A 6cnjD-5nd1B:
undetectable
6cnjE-5nd1B:
undetectable		 6cnjD-5nd1B:
20.45
6cnjE-5nd1B:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 5nd1 CAPSID PROTEIN
CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1;
Rosellinia
necatrix
quadrivirus
1) 		3 / 3 ARG B 446
ARG A 865
ASP B 215
 None
 0.81A 6d8pA-5nd1B:
undetectable		 6d8pA-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		3 / 3 SER A 733
SER A 734
ALA A 795
 None
 0.68A 6dwnC-5nd1A:
0.0		 6dwnC-5nd1A:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 ASP A 254
SER A 628
GLY A 727
ILE A 731
ILE A 626
 None
 1.07A 6ebzB-5nd1A:
undetectable		 6ebzB-5nd1A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 ASP A 254
SER A 628
GLY A 727
ILE A 731
ILE A 626
 None
 1.04A 6ebzD-5nd1A:
undetectable		 6ebzD-5nd1A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 10 ARG A 861
SER A  71
LEU A  66
GLY A  59
VAL A  63
 None
 1.08A 6eu9B-5nd1A:
undetectable		 6eu9B-5nd1A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 ARG A 551
GLU A 548
VAL A 794
ARG A 625
 None
 1.14A 6fbvD-5nd1A:
undetectable		 6fbvD-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 ASP A 254
SER A 628
GLY A 727
ILE A 731
ILE A 626
 None
 1.00A 6gp2A-5nd1A:
undetectable		 6gp2A-5nd1A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 11 ASP A 254
SER A 628
GLY A 727
ILE A 731
ILE A 626
 None
 1.03A 6gp2B-5nd1A:
undetectable		 6gp2B-5nd1A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 5 LEU B 331
THR B 378
THR B 381
GLY B 374
 None
 1.29A 6gtqA-5nd1B:
undetectable		 6gtqA-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 10 MET B 789
THR B 649
PHE B 807
PHE B 588
VAL B 276
 None
 1.29A 6hu9C-5nd1B:
undetectable		 6hu9C-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 ILE A  81
ALA A 773
VAL A 772
ASP A 783
 None
 1.05A 6hu9a-5nd1A:
undetectable
6hu9e-5nd1A:
undetectable		 6hu9a-5nd1A:
undetectable
6hu9e-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 HIS B 686
ARG B 290
HIS B 302
GLU B 285
 None
 1.14A 6mn4A-5nd1B:
undetectable		 6mn4A-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 8 HIS B 686
ARG B 290
HIS B 302
GLU B 285
 None
 1.11A 6mn4D-5nd1B:
undetectable		 6mn4D-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		5 / 9 ILE B 911
ALA B 875
GLY B 874
LEU B 914
GLY B 918
 None
 1.33A 6nm4B-5nd1B:
undetectable		 6nm4B-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6PAH_A_DAHA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 5nd1 CAPSID PROTEIN
(Rosellinia
necatrix
quadrivirus
1) 		4 / 6 HIS B 403
HIS B 220
TYR B 327
GLU B 450
 None
 1.11A 6pahA-5nd1B:
undetectable		 6pahA-5nd1B:
15.41