SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nd5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 209
CYH A 210
SER A 216
LEU A 294
TYR A 258
 TPP  A 801 (-3.5A)
None
None
None
None
 1.28A 1fm6D-5nd5A:
undetectable		 1fm6D-5nd5A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		3 / 3 ARG A 455
ARG A 188
ILE A 473
 None
 0.78A 1uobA-5nd5A:
undetectable		 1uobA-5nd5A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A 294
ILE A 295
VAL A 268
LEU A 206
TRP A 263
 None
 1.36A 1wsvB-5nd5A:
undetectable		 1wsvB-5nd5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 5 ALA A 371
TYR A 373
ALA A 367
TYR A 369
 None
 1.15A 1xl6A-5nd5A:
undetectable
1xl6B-5nd5A:
undetectable		 1xl6A-5nd5A:
18.73
1xl6B-5nd5A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 10 ALA A 620
ILE A 594
PRO A 577
GLU A 615
ILE A 579
 None
 1.40A 2dm6A-5nd5A:
2.8
2dm6B-5nd5A:
2.9		 2dm6A-5nd5A:
19.57
2dm6B-5nd5A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 6 SER A 663
GLY A 609
THR A 610
ARG A 545
 None
 1.22A 2f7fA-5nd5A:
2.6		 2f7fA-5nd5A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 4 ALA A 371
TYR A 373
ALA A 367
TYR A 369
 None
 1.17A 2wlkA-5nd5A:
undetectable
2wlkB-5nd5A:
undetectable		 2wlkA-5nd5A:
18.73
2wlkB-5nd5A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		3 / 3 GLU A  54
VAL A  55
CYH A  58
 None
 1.02A 3fbxA-5nd5A:
undetectable		 3fbxA-5nd5A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 6 PHE A 642
TYR A 649
THR A 593
VAL A 634
 None
 1.31A 3lb3A-5nd5A:
undetectable		 3lb3A-5nd5A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 5 THR A 486
PHE A 487
ARG A 409
LEU A 438
 None
 1.13A 3qelC-5nd5A:
3.3		 3qelC-5nd5A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 177
GLY A 472
LEU A 475
ALA A 223
LEU A 231
 None
 1.10A 3vywA-5nd5A:
2.7		 3vywA-5nd5A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 177
GLY A 472
LEU A 475
ALA A 223
LEU A 231
 None
 1.09A 3vywB-5nd5A:
2.7		 3vywB-5nd5A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 177
GLY A 472
LEU A 475
ALA A 223
LEU A 231
 None
 1.12A 3vywD-5nd5A:
2.9		 3vywD-5nd5A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 8 ARG A 632
LEU A 654
TYR A 649
GLU A 651
 None
 1.43A 3zmdA-5nd5A:
undetectable
3zmdB-5nd5A:
undetectable		 3zmdA-5nd5A:
15.87
3zmdB-5nd5A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		3 / 3 TYR A 335
ASP A 343
ASP A  53
 None
 0.88A 4a6eA-5nd5A:
3.5		 4a6eA-5nd5A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 7 ALA A 506
GLY A 467
GLY A 472
ILE A 473
 None
 0.65A 4eatA-5nd5A:
undetectable		 4eatA-5nd5A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 209
CYH A 210
SER A 216
LEU A 294
TYR A 258
 TPP  A 801 (-3.5A)
None
None
None
None
 1.22A 4emaA-5nd5A:
undetectable		 4emaA-5nd5A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 7 ILE A 579
GLY A 586
ALA A 547
GLU A 551
 None
 0.79A 4g0uB-5nd5A:
2.7		 4g0uB-5nd5A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		3 / 3 PRO A 153
TYR A 123
GLY A 118
 None
 0.68A 4g2zA-5nd5A:
undetectable		 4g2zA-5nd5A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 7 ASP A 492
THR A 491
SER A 534
HIS A 531
 None
 1.47A 4o4dA-5nd5A:
undetectable		 4o4dA-5nd5A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 5 ILE A 685
PHE A 490
HIS A 682
ASP A 515
 None
 1.15A 4rzvB-5nd5A:
undetectable		 4rzvB-5nd5A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 6 GLU A 643
TYR A 675
LEU A 654
PHE A 642
 None
 1.23A 4twdB-5nd5A:
undetectable
4twdC-5nd5A:
undetectable		 4twdB-5nd5A:
15.91
4twdC-5nd5A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 6 GLU A 643
TYR A 675
LEU A 654
PHE A 642
 None
 1.19A 4twdD-5nd5A:
undetectable
4twdE-5nd5A:
undetectable		 4twdD-5nd5A:
15.91
4twdE-5nd5A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 7 GLU A 643
TYR A 675
LEU A 654
PHE A 642
 None
 1.20A 4twdF-5nd5A:
undetectable
4twdJ-5nd5A:
undetectable		 4twdF-5nd5A:
15.91
4twdJ-5nd5A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 6 GLU A 643
TYR A 675
LEU A 654
PHE A 642
 None
 1.06A 4twdF-5nd5A:
undetectable
4twdG-5nd5A:
undetectable		 4twdF-5nd5A:
15.91
4twdG-5nd5A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 6 GLU A 643
TYR A 675
LEU A 654
PHE A 642
 None
 1.19A 4twdI-5nd5A:
undetectable
4twdJ-5nd5A:
undetectable		 4twdI-5nd5A:
15.91
4twdJ-5nd5A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 6 ILE A  59
PRO A  86
ILE A 282
VAL A  95
 None
 0.94A 4zj8A-5nd5A:
undetectable		 4zj8A-5nd5A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 ILE A 469
ALA A 468
ALA A 506
ASN A 174
PHE A 459
 None
 1.31A 4zo1X-5nd5A:
undetectable		 4zo1X-5nd5A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 4 ILE A 517
ARG A 545
TYR A 698
GLU A 613
 None
 1.36A 4zzbD-5nd5A:
1.4		 4zzbD-5nd5A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 609
GLY A 611
ALA A 591
LEU A 616
ALA A 666
 None
 1.27A 5bw4B-5nd5A:
3.3		 5bw4B-5nd5A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 4 VAL A 509
ALA A 485
ILE A 416
THR A 439
 None
 1.16A 5e4dB-5nd5A:
undetectable		 5e4dB-5nd5A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		6 / 12 GLY A 262
GLY A 229
GLY A 224
TRP A 263
ASP A 109
ILE A 232
 None
 1.46A 5e9qA-5nd5A:
undetectable		 5e9qA-5nd5A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		6 / 12 GLY A 262
GLY A 229
GLY A 224
TRP A 263
ASP A 109
ILE A 232
 None
 1.32A 5e9qC-5nd5A:
undetectable		 5e9qC-5nd5A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		6 / 12 GLY A 262
GLY A 229
GLY A 224
TRP A 263
ASP A 109
ILE A 232
 None
 1.36A 5eifC-5nd5A:
undetectable		 5eifC-5nd5A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		6 / 12 GLY A 262
GLY A 229
GLY A 224
TRP A 263
ASP A 109
ILE A 232
 None
 1.43A 5eiwC-5nd5A:
undetectable		 5eiwC-5nd5A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 209
CYH A 210
SER A 216
LEU A 294
TYR A 258
 TPP  A 801 (-3.5A)
None
None
None
None
 1.23A 5ji0D-5nd5A:
undetectable		 5ji0D-5nd5A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1016_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 5 GLY A 609
PRO A 637
TRP A 639
CYH A 638
 None
 1.37A 5nn8A-5nd5A:
undetectable		 5nn8A-5nd5A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A 383
HIS A 184
ALA A 453
SER A 451
ARG A 458
 None
 1.35A 5syfB-5nd5A:
2.4		 5syfB-5nd5A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 ASN A 456
LEU A 457
GLY A 428
GLY A 429
LEU A 480
 None
 0.97A 5uc1B-5nd5A:
undetectable		 5uc1B-5nd5A:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA612_1
(SERUM ALBUMIN)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 TYR A 483
LEU A 396
LEU A 419
LEU A 423
ALA A 559
 None
 1.20A 5v0vA-5nd5A:
undetectable		 5v0vA-5nd5A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		6 / 12 GLY A 262
GLY A 229
GLY A 224
TRP A 263
ASP A 109
ILE A 232
 None
 1.40A 5wz1B-5nd5A:
undetectable		 5wz1B-5nd5A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 12 ALA A  69
GLY A  76
PRO A  81
LEU A 136
ASN A  71
 None
 1.18A 5ybbA-5nd5A:
undetectable		 5ybbA-5nd5A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		3 / 3 HIS A 117
HIS A 152
ARG A 143
 TPP  A 801 (-3.9A)
None
None
 1.04A 6b58A-5nd5A:
3.6		 6b58A-5nd5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 5 ALA A 694
TYR A 698
GLN A 527
ILE A 685
 None
 1.32A 6f6sA-5nd5A:
undetectable
6f6sB-5nd5A:
undetectable		 6f6sA-5nd5A:
8.42
6f6sB-5nd5A:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		4 / 6 GLY A 671
TRP A 672
ALA A 667
LEU A 532
 None
 1.00A 6fosA-5nd5A:
undetectable		 6fosA-5nd5A:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 5nd5 TRANSKETOLASE
(Chlamydomonas
reinhardtii) 		5 / 11 ALA A 309
VAL A 314
ILE A  70
ALA A  66
LEU A 319
 None
 1.31A 6h1lB-5nd5A:
undetectable		 6h1lB-5nd5A:
19.41