SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nd7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		4 / 8 SER C 182
ILE C 186
LEU C 183
LEU C 403
 None
 0.85A 1eupA-5nd7C:
undetectable		 1eupA-5nd7C:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		4 / 7 SER C 163
SER C 500
PHE C 120
ALA C 496
 ANP  C 602 (-3.6A)
None
None
None
 0.89A 1fxvA-5nd7C:
undetectable
1fxvB-5nd7C:
undetectable		 1fxvA-5nd7C:
18.09
1fxvB-5nd7C:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		4 / 8 SER C 163
SER C 500
PHE C 120
ALA C 496
 ANP  C 602 (-3.6A)
None
None
None
 0.87A 1gm7A-5nd7C:
undetectable
1gm7B-5nd7C:
undetectable		 1gm7A-5nd7C:
18.09
1gm7B-5nd7C:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		5 / 11 LEU C 463
ALA C 368
VAL C 466
LEU C 330
LEU C 312
 None
 1.01A 1rlbF-5nd7C:
undetectable		 1rlbF-5nd7C:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		5 / 12 PHE C 305
LEU C 408
ILE C 307
LEU C 463
THR C 464
 None
 1.00A 2bdmA-5nd7C:
undetectable		 2bdmA-5nd7C:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		3 / 3 ARG C 422
GLU C 310
ASP C 460
 None
 0.90A 3g2oA-5nd7C:
undetectable		 3g2oA-5nd7C:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		4 / 8 TYR C 158
PHE C 499
GLY C 427
ILE C 429
 None
 0.87A 3ihzB-5nd7C:
undetectable		 3ihzB-5nd7C:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		3 / 3 THR C 161
ASN C 162
GLU C 412
 ANP  C 602 ( 4.3A)
None
None
 0.81A 3v4tA-5nd7C:
0.5
3v4tC-5nd7C:
undetectable		 3v4tA-5nd7C:
23.35
3v4tC-5nd7C:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		4 / 5 TRP C 355
GLY C 171
ALA C 176
PHE C 383
 None
 1.50A 3wqwA-5nd7C:
undetectable		 3wqwA-5nd7C:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		3 / 3 ARG C 386
TRP C 301
ILE C 400
 None
 0.80A 4mwxA-5nd7C:
undetectable		 4mwxA-5nd7C:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		3 / 3 ARG C 459
ILE C 456
PHE C 458
 None
 0.73A 5kirA-5nd7C:
undetectable		 5kirA-5nd7C:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QJQ_A_K1SA304_0
(ADP-SUGAR
PYROPHOSPHATASE)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		4 / 5 GLU C 352
TRP C 355
VAL C 351
LEU C 179
 None
 1.34A 5qjqA-5nd7C:
undetectable
5qjqB-5nd7C:
undetectable		 5qjqA-5nd7C:
18.66
5qjqB-5nd7C:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QJQ_B_K1SB304_0
(ADP-SUGAR
PYROPHOSPHATASE)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		4 / 5 TRP C 355
VAL C 351
LEU C 179
GLU C 352
 None
 1.34A 5qjqA-5nd7C:
undetectable
5qjqB-5nd7C:
undetectable		 5qjqA-5nd7C:
18.66
5qjqB-5nd7C:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QJQ_C_K1SC305_0
(ADP-SUGAR
PYROPHOSPHATASE)		 5nd7 KINESIN-LIKE PROTEIN
KIF20A
(Mus
musculus) 		4 / 5 GLU C 352
TRP C 355
VAL C 351
LEU C 179
 None
 1.35A 5qjqC-5nd7C:
0.0
5qjqD-5nd7C:
0.0		 5qjqC-5nd7C:
18.66
5qjqD-5nd7C:
18.66