SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ndl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		5 / 12 LEU A 225
GLY A 105
GLY A 103
GLY A 223
GLY A 224
 None
 0.79A 3axzA-5ndlA:
undetectable		 3axzA-5ndlA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		4 / 4 ASP A 116
LEU A 117
ARG A 203
THR A 198
 None
None
NAG  A 303 ( 4.0A)
None
 1.41A 4kjjA-5ndlA:
undetectable		 4kjjA-5ndlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		4 / 4 ASP A 116
LEU A 117
ARG A 203
THR A 198
 None
None
NAG  A 303 ( 4.0A)
None
 1.44A 4kjkA-5ndlA:
undetectable		 4kjkA-5ndlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		5 / 9 VAL A  74
ALA A  75
TYR A 228
GLY A 126
GLY A 231
 None
 1.22A 4mm5A-5ndlA:
undetectable		 4mm5A-5ndlA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		4 / 5 ASP A 116
LEU A 117
ARG A 203
THR A 198
 None
None
NAG  A 303 ( 4.0A)
None
 1.42A 4p3qA-5ndlA:
undetectable		 4p3qA-5ndlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		4 / 5 GLN A 261
SER A 262
ASP A 118
ASP A 141
 None
 1.26A 4qtuB-5ndlA:
undetectable		 4qtuB-5ndlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		4 / 5 GLN A 261
SER A 262
ASP A 118
ASP A 141
 None
 1.31A 4qtuD-5ndlA:
undetectable		 4qtuD-5ndlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		4 / 4 ALA A 101
VAL A 107
GLY A 210
THR A 226
 None
 1.13A 4ubeA-5ndlA:
undetectable		 4ubeA-5ndlA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		5 / 12 LEU A 225
GLY A 105
GLY A 103
GLY A 223
GLY A 224
 None
 0.78A 4yvgA-5ndlA:
undetectable		 4yvgA-5ndlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		4 / 5 GLY A 223
PRO A 156
GLN A 157
THR A 104
 None
 1.21A 5h5fA-5ndlA:
undetectable		 5h5fA-5ndlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		4 / 6 ASP A 118
GLY A 138
ASP A 141
ASP A 116
 None
 1.29A 5hp1A-5ndlA:
undetectable		 5hp1A-5ndlA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		4 / 6 ASP A 118
GLY A 140
ASP A 141
ASP A 116
 None
 1.27A 5hp1A-5ndlA:
undetectable		 5hp1A-5ndlA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		5 / 12 ILE A 110
VAL A 120
VAL A 172
PHE A  87
TYR A  43
 None
 1.27A 5igiA-5ndlA:
undetectable		 5igiA-5ndlA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		5 / 12 GLY A 105
ILE A 219
ALA A 208
ASP A 211
TYR A 228
 None
None
None
NAG  A 302 ( 4.7A)
None
 1.12A 5kvaA-5ndlA:
undetectable		 5kvaA-5ndlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		5 / 12 GLY A 105
ILE A 219
ALA A 208
ASP A 211
TYR A 228
 None
None
None
NAG  A 302 ( 4.7A)
None
 1.12A 5kvaB-5ndlA:
undetectable		 5kvaB-5ndlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		5 / 12 PHE A 137
PHE A  72
ALA A  70
LEU A 202
THR A 134
 NAG  A 304 ( 4.3A)
None
None
None
None
 1.16A 5tl8A-5ndlA:
undetectable		 5tl8A-5ndlA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5ndl CRH-LIKE PROTEIN
(Aspergillus
fumigatus) 		5 / 12 LEU A 225
GLY A 105
GLY A 103
GLY A 223
GLY A 224
 None
 0.81A 5wyqA-5ndlA:
undetectable		 5wyqA-5ndlA:
undetectable