SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nen'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 5nen LIPASE C
(Serratia
marcescens) 		4 / 6 LEU A 174
VAL A 208
VAL A 201
GLN A 202
 None
 1.06A 1e7aB-5nenA:
undetectable		 1e7aB-5nenA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5nen LIPASE C
(Serratia
marcescens) 		5 / 10 ASP A 213
SER A 210
SER A 211
ASN A 209
ARG A 218
 None
 1.32A 1mehA-5nenA:
undetectable		 1mehA-5nenA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 5nen LIPASE C
(Serratia
marcescens) 		4 / 7 ALA A  78
ASP A 268
GLY A  51
ILE A  52
 None
 0.66A 5kqyB-5nenA:
undetectable		 5kqyB-5nenA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5nen LIPASE C
(Serratia
marcescens) 		4 / 4 SER A 256
ALA A 255
GLN A  88
THR A  92
 None
 1.36A 5n0rA-5nenA:
undetectable		 5n0rA-5nenA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5nen LIPASE C
(Serratia
marcescens) 		4 / 4 SER A 256
ALA A 255
GLN A  88
THR A  92
 None
 1.35A 5n0sA-5nenA:
undetectable		 5n0sA-5nenA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5nen LIPASE C
(Serratia
marcescens) 		4 / 4 SER A 256
ALA A 255
GLN A  88
THR A  92
 None
 1.35A 5n0wA-5nenA:
undetectable		 5n0wA-5nenA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5nen LIPASE C
(Serratia
marcescens) 		4 / 5 SER A 256
ALA A 255
GLN A  88
THR A  92
 None
 1.36A 5n0wB-5nenA:
undetectable		 5n0wB-5nenA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5nen LIPASE C
(Serratia
marcescens) 		4 / 4 SER A 256
ALA A 255
GLN A  88
THR A  92
 None
 1.37A 5n0xA-5nenA:
undetectable		 5n0xA-5nenA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5nen LIPASE C
(Serratia
marcescens) 		4 / 5 SER A 256
ALA A 255
GLN A  88
THR A  92
 None
 1.37A 5n4iA-5nenA:
undetectable		 5n4iA-5nenA:
21.01