SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ner'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 5ner O PANASIA VP2
(Foot-and-mouth
disease
virus) 		4 / 9 ILE 2 132
ALA 2 124
VAL 2 180
CYH 2  78
 None
 0.96A 2vufB-5ner2:
undetectable		 2vufB-5ner2:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 5ner O PANASIA VP2
(Foot-and-mouth
disease
virus) 		3 / 3 PHE 2  62
TYR 2 171
TYR 2  91
 None
 1.00A 4ffwA-5ner2:
undetectable		 4ffwA-5ner2:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 5ner O PANASIA VP2
(Foot-and-mouth
disease
virus) 		4 / 4 VAL 2 109
ALA 2 156
ASN 2 153
GLN 2 146
 None
 1.46A 4zgfA-5ner2:
undetectable		 4zgfA-5ner2:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 5ner O PANASIA VP2
(Foot-and-mouth
disease
virus) 		3 / 3 ILE 2 158
THR 2 159
PRO 2 144
 None
 0.50A 6ncsA-5ner2:
undetectable		 6ncsA-5ner2:
18.75