SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5net'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5net O1 MANISA VP3
(Foot-and-mouth
disease
virus) 		5 / 12 THR 3 112
VAL 3 200
VAL 3 201
PHE 3  57
TYR 3 121
 None
 1.39A 2y04B-5net3:
undetectable		 2y04B-5net3:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 5net O1 MANISA VP3
(Foot-and-mouth
disease
virus) 		5 / 12 THR 3 112
VAL 3 200
VAL 3 201
PHE 3  57
TYR 3 121
 None
 1.37A 3d4sA-5net3:
undetectable		 3d4sA-5net3:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 5net O1 MANISA VP3
(Foot-and-mouth
disease
virus) 		4 / 6 PHE 3 209
ASN 3 106
ALA 3 203
THR 3  89
 None
 1.15A 3t3sB-5net3:
undetectable		 3t3sB-5net3:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 5net O1 MANISA VP3
(Foot-and-mouth
disease
virus) 		4 / 8 PHE 3 209
ASN 3 106
ALA 3 203
THR 3  89
 None
 1.08A 3t3sE-5net3:
undetectable		 3t3sE-5net3:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 5net O1 MANISA VP3
(Foot-and-mouth
disease
virus) 		4 / 5 LEU 3  45
ASP 3  46
TYR 3  98
LEU 3  94
 None
 1.21A 4wozF-5net3:
undetectable
4wozH-5net3:
undetectable		 4wozF-5net3:
21.40
4wozH-5net3:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5net O1 MANISA VP3
(Foot-and-mouth
disease
virus) 		4 / 5 GLU 3  49
THR 3  89
HIS 3  85
LEU 3 107
 None
 1.27A 5axaC-5net3:
undetectable		 5axaC-5net3:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 5net O1 MANISA VP3
(Foot-and-mouth
disease
virus) 		3 / 3 TYR 3 125
TYR 3 101
GLN 3 181
 None
 0.87A 5jsdA-5net3:
1.2
5jsdB-5net3:
1.2		 5jsdA-5net3:
15.53
5jsdB-5net3:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 5net O1 MANISA VP3
(Foot-and-mouth
disease
virus) 		3 / 3 TYR 3 125
TYR 3 101
GLN 3 181
 None
 0.89A 5jsdB-5net3:
1.2
5jsdC-5net3:
undetectable		 5jsdB-5net3:
15.53
5jsdC-5net3:
15.53