SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5neu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 8 GLY A 378
LEU A 383
VAL A 386
PHE A   1
 None
 1.17A 1gsfA-5neuA:
undetectable		 1gsfA-5neuA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 8 GLY A 378
LEU A 383
VAL A 386
PHE A   1
 None
 1.17A 1gsfB-5neuA:
undetectable		 1gsfB-5neuA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 8 GLY A 378
LEU A 383
VAL A 386
PHE A   1
 None
 1.18A 1gsfD-5neuA:
undetectable		 1gsfD-5neuA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		3 / 3 ASP A 353
PHE A 581
ASN A   2
 None
 0.75A 1sg9B-5neuA:
undetectable		 1sg9B-5neuA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 7 LEU A  57
VAL A  38
GLY A  39
ASP A 430
 None
 0.97A 1t88A-5neuA:
undetectable		 1t88A-5neuA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_A_ROFA101_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 ASP A  24
LEU A  37
TYR A  11
ILE A 414
SER A  62
 None
 0.97A 1xmuA-5neuA:
undetectable		 1xmuA-5neuA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_B_ROFB102_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 ASP A  24
LEU A  37
TYR A  11
ILE A 414
SER A  62
 None
 0.98A 1xmuB-5neuA:
undetectable		 1xmuB-5neuA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 ASP A  24
LEU A  37
TYR A  11
ILE A 414
SER A  62
 None
 0.97A 1xoqA-5neuA:
undetectable		 1xoqA-5neuA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 ASP A  24
LEU A  37
TYR A  11
ILE A 414
SER A  62
 None
 0.96A 1xoqB-5neuA:
undetectable		 1xoqB-5neuA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 6 TRP A  93
GLY A  20
PHE A 427
SER A 407
 None
 1.40A 2a3cB-5neuA:
undetectable		 2a3cB-5neuA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 11 LEU A  57
ALA A 432
GLY A 428
PRO A  41
ALA A  40
 None
 1.07A 2idwA-5neuA:
undetectable		 2idwA-5neuA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 6 ILE A 527
PRO A 576
LEU A 578
ILE A 441
 None
 0.95A 2q83B-5neuA:
2.9		 2q83B-5neuA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 GLY A 258
LEU A 183
ALA A 166
PHE A 163
VAL A 228
 None
 1.28A 2yvlC-5neuA:
undetectable		 2yvlC-5neuA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 11 VAL A 424
GLY A 425
VAL A  23
ILE A 360
ALA A 361
 None
 0.89A 2yy8A-5neuA:
undetectable
2yy8B-5neuA:
undetectable		 2yy8A-5neuA:
16.64
2yy8B-5neuA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 6 ALA A 540
LEU A 542
SER A 471
VAL A 475
 None
 0.86A 3d2tB-5neuA:
undetectable		 3d2tB-5neuA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		3 / 3 THR A  64
SER A  63
PHE A  35
 None
 0.79A 3d4sA-5neuA:
undetectable		 3d4sA-5neuA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 VAL A  38
GLY A  39
GLY A  95
PHE A 129
SER A 407
 None
 1.22A 3dh0A-5neuA:
undetectable		 3dh0A-5neuA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 ILE A 557
ALA A 590
LEU A 454
GLU A 537
SER A 471
 None
 1.45A 3eigA-5neuA:
undetectable		 3eigA-5neuA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 GLY A 485
ASN A 417
GLY A 348
ALA A 411
GLY A 418
 None
 1.02A 3hs6B-5neuA:
undetectable		 3hs6B-5neuA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 LEU A 170
TYR A 139
LEU A 106
ILE A 184
GLY A 173
 None
 1.12A 3kk6A-5neuA:
undetectable		 3kk6A-5neuA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 LEU A 170
TYR A 139
LEU A 106
ILE A 184
GLY A 173
 None
 1.11A 3kk6B-5neuA:
undetectable		 3kk6B-5neuA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 11 LEU A 170
LEU A 171
GLY A 158
SER A  97
LEU A 106
 None
 1.27A 3ndvA-5neuA:
undetectable
3ndvB-5neuA:
undetectable		 3ndvA-5neuA:
23.01
3ndvB-5neuA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 11 GLY A 158
SER A  97
LEU A 106
LEU A 170
LEU A 171
 None
 1.31A 3ndvC-5neuA:
undetectable
3ndvD-5neuA:
undetectable		 3ndvC-5neuA:
23.01
3ndvD-5neuA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 ALA A 361
LEU A 391
GLY A 371
TYR A 364
ALA A 397
 None
 1.30A 3tm4A-5neuA:
undetectable		 3tm4A-5neuA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 ALA A 361
LEU A 391
GLY A 371
TYR A 364
ALA A 397
 None
 1.33A 3tm4B-5neuA:
undetectable		 3tm4B-5neuA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 ILE A 433
VAL A   5
SER A 388
ALA A 359
LEU A 350
 None
 1.18A 3w67C-5neuA:
undetectable		 3w67C-5neuA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 6 SER A 185
ARG A 168
GLY A 235
ASP A 234
GLY A 229
 None
 1.24A 4koeA-5neuA:
undetectable
4koeB-5neuA:
undetectable
4koeC-5neuA:
undetectable		 4koeA-5neuA:
23.88
4koeB-5neuA:
23.88
4koeC-5neuA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 7 ARG A 168
SER A 185
GLY A 235
ASP A 234
GLY A 229
 None
 1.22A 4koeA-5neuA:
undetectable
4koeB-5neuA:
undetectable
4koeD-5neuA:
undetectable		 4koeA-5neuA:
23.88
4koeB-5neuA:
23.88
4koeD-5neuA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		3 / 3 SER A 241
ALA A 227
VAL A 228
 None
 0.58A 4o2bA-5neuA:
undetectable		 4o2bA-5neuA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 7 LYS A 369
LYS A 370
TYR A 374
LEU A 391
 None
 1.22A 4yv5B-5neuA:
undetectable		 4yv5B-5neuA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 6 GLY A 235
ASP A 234
GLY A 229
SER A 185
ARG A 168
 None
 1.18A 4z53A-5neuA:
undetectable
4z53B-5neuA:
undetectable		 4z53A-5neuA:
23.06
4z53B-5neuA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 7 ARG A 168
GLY A 235
ASP A 234
GLY A 229
SER A 185
 None
 1.22A 4z53A-5neuA:
undetectable
4z53B-5neuA:
undetectable		 4z53A-5neuA:
23.06
4z53B-5neuA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 8 SER A 225
GLY A 242
ALA A 273
GLY A 251
 None
 0.84A 5albL-5neuA:
undetectable		 5albL-5neuA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 MET A 559
ILE A 586
LEU A 497
VAL A 449
VAL A 475
 None
 1.07A 5bykA-5neuA:
undetectable		 5bykA-5neuA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 GLY A 378
LEU A 422
ILE A 433
TYR A 435
GLY A 405
 None
 1.11A 5eskA-5neuA:
undetectable		 5eskA-5neuA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 PRO A  69
THR A  46
GLN A  47
GLY A  54
SER A  17
 None
 1.40A 5hfjG-5neuA:
undetectable		 5hfjG-5neuA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 7 GLY A 425
TRP A 395
ASP A 430
TYR A  18
 None
 1.25A 5vlmG-5neuA:
undetectable		 5vlmG-5neuA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 5 VAL A 243
PRO A 174
GLY A 181
TYR A 221
 None
 1.13A 5x80A-5neuA:
undetectable
5x80B-5neuA:
undetectable		 5x80A-5neuA:
14.82
5x80B-5neuA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 5 PRO A 174
GLY A 181
TYR A 221
VAL A 243
 None
 1.19A 5x80C-5neuA:
undetectable
5x80D-5neuA:
undetectable		 5x80C-5neuA:
14.82
5x80D-5neuA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 11 GLY A 269
GLN A 314
GLU A 270
THR A 328
GLY A 277
 None
 1.46A 5z84A-5neuA:
undetectable
5z84B-5neuA:
undetectable
5z84T-5neuA:
undetectable		 5z84A-5neuA:
23.10
5z84B-5neuA:
15.76
5z84T-5neuA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 11 GLY A 269
GLN A 314
GLU A 270
THR A 328
GLY A 277
 None
 1.49A 5z86A-5neuA:
undetectable
5z86B-5neuA:
undetectable
5z86T-5neuA:
undetectable		 5z86A-5neuA:
23.10
5z86B-5neuA:
15.76
5z86T-5neuA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 SER A 225
SER A 316
THR A 329
PHE A 267
VAL A 253
 None
 0.99A 6a93B-5neuA:
undetectable		 6a93B-5neuA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		5 / 12 MET A 559
ILE A 586
LEU A 497
VAL A 449
VAL A 475
 None
 1.15A 6b52A-5neuA:
undetectable		 6b52A-5neuA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5neu INTEGRIN ALPHA-V
(Homo
sapiens) 		4 / 6 LEU A 350
ASP A 351
ASP A 353
GLN A 580
 None
 1.38A 6g31J-5neuA:
undetectable		 6g31J-5neuA:
9.94