SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ney'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QK8_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5ney FUCOSE-BINDING
LECTIN II (PA-IIL)
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  55
VAL A  32
ILE A 109
LEU A   8
PRO A   9
 None
 1.24A 2qk8A-5neyA:
undetectable		 2qk8A-5neyA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 5ney FUCOSE-BINDING
LECTIN II (PA-IIL)
(Pseudomonas
aeruginosa) 		4 / 8 VAL A  28
VAL A  49
PHE A  19
VAL A  65
 None
 0.81A 3fhxB-5neyA:
undetectable		 3fhxB-5neyA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5ney FUCOSE-BINDING
LECTIN II (PA-IIL)
(Pseudomonas
aeruginosa) 		3 / 3 SER A  23
GLY A  24
GLN A  43
 ZDC  A 201 (-2.7A)
None
None
 0.63A 3v4tH-5neyA:
undetectable		 3v4tH-5neyA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 5ney FUCOSE-BINDING
LECTIN II (PA-IIL)
(Pseudomonas
aeruginosa) 		4 / 6 VAL A  30
ALA A  38
GLN A  53
VAL A  16
 None
 1.05A 5i8fA-5neyA:
undetectable		 5i8fA-5neyA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 5ney FUCOSE-BINDING
LECTIN II (PA-IIL)
(Pseudomonas
aeruginosa) 		5 / 10 PRO A  73
GLY A  51
THR A  17
ILE A  50
ALA A 105
 None
 1.15A 5vyhA-5neyA:
undetectable		 5vyhA-5neyA:
15.82