SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nf2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY5_A_ACTA600_0
(RIBONUCLEASE A)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 4 HIS A 370
VAL A 481
ASN A 368
THR A 386
 None
 1.44A 1dy5A-5nf2A:
undetectable		 1dy5A-5nf2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 4 GLY A 527
ASP A 524
GLY A 427
THR A 440
 None
 1.08A 1hxbB-5nf2A:
undetectable		 1hxbB-5nf2A:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 7 VAL A 481
LEU A 366
LEU A 365
ALA A 323
 None
 0.77A 1j8uA-5nf2A:
undetectable		 1j8uA-5nf2A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 5 ASP A 139
GLU A  93
LEU A 147
LEU A 148
 None
 1.03A 1np1A-5nf2A:
undetectable		 1np1A-5nf2A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		5 / 12 GLY A 302
ASN A 368
GLN A 279
HIS A 370
PHE A 305
 None
 1.45A 1qu3A-5nf2A:
undetectable		 1qu3A-5nf2A:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		5 / 11 GLU A 318
ALA A 316
ASP A 321
PRO A 506
PHE A 312
 None
 1.29A 2admA-5nf2A:
undetectable		 2admA-5nf2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		3 / 3 GLU A 327
GLU A 355
ASN A 358
 None
 0.88A 3lp9B-5nf2A:
undetectable
3lp9D-5nf2A:
undetectable		 3lp9B-5nf2A:
19.56
3lp9D-5nf2A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		5 / 12 MET A  80
VAL A 131
PRO A 117
VAL A  76
TYR A 101
 None
 1.41A 3p6gA-5nf2A:
undetectable		 3p6gA-5nf2A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_NCAA1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 7 THR A 532
HIS A 453
ASN A 500
TYR A 463
 None
 1.49A 4a3uA-5nf2A:
undetectable		 4a3uA-5nf2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_NCAB1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 7 THR A 532
HIS A 453
ASN A 500
TYR A 463
 None
 1.47A 4a3uB-5nf2A:
undetectable		 4a3uB-5nf2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		5 / 12 VAL A 547
ILE A 489
ILE A 252
TYR A 462
VAL A 389
 None
 1.01A 4a97B-5nf2A:
undetectable
4a97C-5nf2A:
undetectable		 4a97B-5nf2A:
15.77
4a97C-5nf2A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 5 PRO A 117
ASP A 562
ILE A  78
VAL A 234
 None
 1.23A 4hytA-5nf2A:
undetectable		 4hytA-5nf2A:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 8 PHE A 432
PHE A 424
GLY A 498
ILE A 494
 None
 0.95A 4qogA-5nf2A:
undetectable
4qogB-5nf2A:
undetectable		 4qogA-5nf2A:
15.38
4qogB-5nf2A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 5 ALA A 172
TYR A 322
PRO A 508
PHE A 312
 None
 1.23A 4ze2A-5nf2A:
undetectable		 4ze2A-5nf2A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 4 LYS A 363
ASP A 520
GLU A 327
THR A 339
 None
 1.24A 5d4uA-5nf2A:
undetectable		 5d4uA-5nf2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 4 LYS A 363
ASP A 520
GLU A 327
THR A 339
 None
 1.23A 5d4uB-5nf2A:
undetectable		 5d4uB-5nf2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 4 LYS A 363
ASP A 520
GLU A 327
THR A 339
 None
 1.25A 5d4uC-5nf2A:
undetectable		 5d4uC-5nf2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN MJ0489)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 4 LYS A 363
ASP A 520
GLU A 327
THR A 339
 None
 1.24A 5d4uD-5nf2A:
undetectable		 5d4uD-5nf2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5nf2 MINOR FIMBRIUM
SUBUNIT MFA1
(Porphyromonas
gingivalis) 		4 / 5 TYR A 347
SER A 361
ALA A 359
THR A 339
 None
 1.39A 5n0wB-5nf2A:
undetectable		 5n0wB-5nf2A:
undetectable