SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nf4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		4 / 8 GLN A 188
GLU A 182
ASP A 340
ARG A 319
 None
 1.22A 1dtlA-5nf4A:
undetectable		 1dtlA-5nf4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		3 / 3 ALA A 240
VAL A 238
TRP A 244
 None
 0.70A 1grmA-5nf4A:
undetectable		 1grmA-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		3 / 3 ALA A 240
VAL A 238
TRP A 244
 None
 0.70A 1grmB-5nf4A:
undetectable		 1grmB-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		3 / 3 ALA A 240
VAL A 238
TRP A 244
 None
 0.90A 1jo3A-5nf4A:
undetectable		 1jo3A-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		3 / 3 ALA A 240
VAL A 238
TRP A 244
 None
 0.90A 1jo3B-5nf4A:
undetectable		 1jo3B-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		3 / 3 ALA A 240
VAL A 238
TRP A 244
 None
 0.86A 1jo4A-5nf4A:
undetectable		 1jo4A-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		3 / 3 ALA A 240
VAL A 238
TRP A 244
 None
 0.86A 1jo4B-5nf4A:
undetectable		 1jo4B-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		3 / 3 ALA A 240
VAL A 238
TRP A 244
 None
 0.91A 1magA-5nf4A:
undetectable		 1magA-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		3 / 3 ALA A 240
VAL A 238
TRP A 244
 None
 0.92A 1magB-5nf4A:
undetectable		 1magB-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		4 / 7 PHE A 108
LEU A 101
PHE A 110
SER A  85
 None
 1.03A 1wrlA-5nf4A:
undetectable
1wrlB-5nf4A:
undetectable		 1wrlA-5nf4A:
22.11
1wrlB-5nf4A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		4 / 7 PHE A 108
LEU A 101
PHE A 110
SER A  85
 None
 1.18A 1wrlE-5nf4A:
undetectable		 1wrlE-5nf4A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		3 / 3 GLU A 209
VAL A 233
CYH A 211
 None
 1.01A 3fbxA-5nf4A:
undetectable		 3fbxA-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		5 / 10 VAL A  71
LEU A  38
VAL A  40
VAL A  99
LEU A 101
 None
 1.02A 3gwxA-5nf4A:
undetectable		 3gwxA-5nf4A:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		4 / 8 ASN A 222
GLU A 225
ILE A 252
ASN A 271
 None
 1.02A 4d33A-5nf4A:
undetectable		 4d33A-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		4 / 7 ASN A 222
GLU A 225
ILE A 252
ASN A 271
 None
 1.05A 4d33B-5nf4A:
undetectable		 4d33B-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		4 / 8 ASN A 222
GLU A 225
ILE A 252
ASN A 271
 None
 1.00A 4d39A-5nf4A:
undetectable		 4d39A-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		4 / 7 ASN A 222
GLU A 225
ILE A 252
ASN A 271
 None
 1.10A 4d39B-5nf4A:
undetectable		 4d39B-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		3 / 3 TRP A 341
GLU A  61
ASP A 195
 None
 0.98A 5gqbA-5nf4A:
4.1		 5gqbA-5nf4A:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		4 / 4 LYS A 304
LEU A 306
ALA A 303
LEU A 307
 None
 1.43A 6gnrA-5nf4A:
4.9		 6gnrA-5nf4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 5nf4 MINOR FIMBRIUM TIP
SUBUNIT MFA3
(Porphyromonas
gingivalis) 		4 / 4 LYS A 304
LEU A 306
ALA A 303
LEU A 307
 None
 1.41A 6gnrB-5nf4A:
5.1		 6gnrB-5nf4A:
undetectable