SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ng6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM4_A_DXCA1002_0 (MAJOR POLLEN ALLERGEN BET V 1-L)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	PHE A1005 VAL A1003 ILE A 944 SER A 986 LEU A1031	None None None G B -2 ( 3.2A) None	1.27A	1fm4A-5ng6A: undetectable	1fm4A-5ng6A: 7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OIP_A_VIVA1278_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	ILE A 195 LEU A 208 ILE A 278 LEU A 66 ILE A 113	None	0.88A	1oipA-5ng6A: undetectable	1oipA-5ng6A: 11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_A_FOLA605_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	VAL A1004 LEU A1035 ILE A 900 LEU A 904 TYR A1076	None	1.09A	1qzfA-5ng6A: undetectable	1qzfA-5ng6A: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_B_FOLB609_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	VAL A1004 LEU A1035 ILE A 900 LEU A 904 TYR A1076	None	1.09A	1qzfB-5ng6A: undetectable	1qzfB-5ng6A: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_C_FOLC613_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	VAL A1004 LEU A1035 ILE A 900 LEU A 904 TYR A1076	None	1.09A	1qzfC-5ng6A: undetectable	1qzfC-5ng6A: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_D_FOLD617_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	VAL A1004 LEU A1035 ILE A 900 LEU A 904 TYR A1076	None	1.09A	1qzfD-5ng6A: undetectable	1qzfD-5ng6A: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_E_FOLE621_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	VAL A1004 LEU A1035 ILE A 900 LEU A 904 TYR A1076	None	1.09A	1qzfE-5ng6A: undetectable	1qzfE-5ng6A: 17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RJD_B_SAMB802_1 (CARBOXY METHYL TRANSFERASE FOR PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 6	ARG A1016 ASP A1253 ASP A 939 GLU A 920	None	1.27A	1rjdB-5ng6A: undetectable	1rjdB-5ng6A: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RJD_C_SAMC803_1 (CARBOXY METHYL TRANSFERASE FOR PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 6	ARG A1016 ASP A1253 ASP A 939 GLU A 920	None	1.24A	1rjdC-5ng6A: undetectable	1rjdC-5ng6A: 12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_J_BEZJ5041_0 (CES1 PROTEIN)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 4	GLY A 701 SER A 695 ILE A 750 HIS A 697	None	1.24A	1yajJ-5ng6A: undetectable	1yajJ-5ng6A: 16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CL5_B_SAMB1217_1 (CATECHOL O-METHYLTRANSFERASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 6	SER A 322 TYR A 272 SER A 80 GLN A 77	None	0.87A	2cl5B-5ng6A: undetectable	2cl5B-5ng6A: 10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_A_MTXA605_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	VAL A1004 LEU A1035 ILE A 900 LEU A 904 TYR A1076	None	1.15A	2oipA-5ng6A: undetectable	2oipA-5ng6A: 17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QE6_A_SAMA400_1 (UNCHARACTERIZED PROTEIN TFU_2867)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	3 / 3	ASN A 464 ARG A 467 ASP A 408	None	0.98A	2qe6A-5ng6A: undetectable	2qe6A-5ng6A: 12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QE6_B_SAMB400_1 (UNCHARACTERIZED PROTEIN TFU_2867)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	3 / 3	ASN A 464 ARG A 467 ASP A 408	None	0.99A	2qe6B-5ng6A: undetectable	2qe6B-5ng6A: 12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QMZ_A_LDPA501_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 7	GLY A 761 PHE A 741 ILE A 728 PHE A 753	None	1.03A	2qmzA-5ng6A: undetectable 2qmzB-5ng6A: undetectable	2qmzA-5ng6A: 10.54 2qmzB-5ng6A: 10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V7B_B_BEZB1529_0 (BENZOATE-COENZYME A LIGASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 9	ALA A 924 TYR A 925 ALA A1256 GLY A1258 HIS A 922	None	1.35A	2v7bB-5ng6A: undetectable	2v7bB-5ng6A: 17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDB_A_NPSA1591_1 (SERUM ALBUMIN)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 8	PHE A 378 LEU A 377 PHE A 565 TYR A 562	None	0.85A	2vdbA-5ng6A: undetectable	2vdbA-5ng6A: 18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W3M_B_FOLB1188_0 (DIHYDROFOLATE REDUCTASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	ALA A 416 LEU A 460 PHE A 407 ASN A 481 THR A 415	None	1.22A	2w3mB-5ng6A: undetectable	2w3mB-5ng6A: 8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_A_DIFA1375_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	3 / 3	LEU A 985 TYR A 984 GLN A 987	None None A B -3 ( 3.6A)	0.65A	2wekA-5ng6A: undetectable	2wekA-5ng6A: 13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YVL_B_SAMB602_1 (HYPOTHETICAL PROTEIN)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	3 / 3	GLU A1225 ASP A1253 TYR A 925	None	0.81A	2yvlB-5ng6A: undetectable	2yvlB-5ng6A: 11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZVJ_A_SAMA301_1 (CATECHOL O-METHYLTRANSFERASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 6	SER A 322 TYR A 272 SER A 80 GLN A 77	None	0.91A	2zvjA-5ng6A: undetectable	2zvjA-5ng6A: 10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A9E_B_REAB1_1 (RETINOIC ACID RECEPTOR ALPHA)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 11	PHE A 543 ILE A 478 PHE A 393 PHE A 482 LEU A 374	None	1.36A	3a9eB-5ng6A: undetectable	3a9eB-5ng6A: 11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AI9_X_SAMX501_0 (UPF0217 PROTEIN MJ1640)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 9	ILE A 159 LEU A 142 SER A 145 GLU A 151 LEU A 152	None	1.06A	3ai9X-5ng6A: undetectable	3ai9X-5ng6A: 9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IA4_B_MTXB164_1 (DIHYDROFOLATE REDUCTASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	MET A 352 LEU A 529 GLN A 532 SER A 503 ILE A 502	None	1.16A	3ia4B-5ng6A: undetectable	3ia4B-5ng6A: 7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LTW_A_HLZA300_1 (ARYLAMINE N-ACETYLTRANSFERASE NAT)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 6	PHE A 786 TYR A 784 THR A 618 PHE A 600	None	1.31A	3ltwA-5ng6A: undetectable	3ltwA-5ng6A: 11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OWX_A_XRAA233_2 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 5	PHE A1126 ILE A1144 PHE A1128 PHE A1112	None	0.96A	3owxB-5ng6A: undetectable	3owxB-5ng6A: 10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9C_A_ECLA452_1 (CYTOCHROME P450 164A2)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	LEU A 830 LEU A 630 ALA A 606 ASN A 617 LEU A 783	None	1.20A	3r9cA-5ng6A: undetectable	3r9cA-5ng6A: 14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V3O_B_T1CB405_1 (TETX2 PROTEIN)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	ASN A1093 GLY A1090 ALA A1079 GLY A1080 GLU A1006	None	1.22A	3v3oB-5ng6A: undetectable	3v3oB-5ng6A: 14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V3O_B_T1CB405_1 (TETX2 PROTEIN)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	GLN A1296 ASN A1093 GLY A1090 GLY A1080 GLU A1006	None	1.25A	3v3oB-5ng6A: undetectable	3v3oB-5ng6A: 14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W68_D_VIVD301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	6 / 12	LEU A 830 ILE A 657 ILE A 620 VAL A 632 LEU A 783 PHE A 600	None	1.42A	3w68D-5ng6A: undetectable	3w68D-5ng6A: 10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A6N_A_T1CA392_1 (TETX2 PROTEIN)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 11	ASN A1093 GLY A1090 ALA A1079 GLY A1080 GLU A1006	None	1.03A	4a6nA-5ng6A: undetectable	4a6nA-5ng6A: 14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AZT_A_SAMA1472_0 (METHYLTRANSFERASE WBDD)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	GLY A1263 ALA A1259 ILE A 913 VAL A1004 ILE A1002	None	1.08A	4aztA-5ng6A: undetectable	4aztA-5ng6A: 17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DM8_A_REAA501_1 (RETINOIC ACID RECEPTOR BETA)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 11	PHE A 123 LEU A 329 PHE A 119 SER A 116 ILE A 54	None	0.89A	4dm8A-5ng6A: undetectable	4dm8A-5ng6A: 11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F93_B_SANB3004_1 (U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 8	GLU A1175 GLU A1167 GLY A1148 SER A1149	None	1.01A	4f93B-5ng6A: undetectable	4f93B-5ng6A: 21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FJP_A_NPSA711_1 (LACTOTRANSFERRIN)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 6	GLY A1090 PRO A1087 TYR A1260 GLY A1258	None	0.89A	4fjpA-5ng6A: undetectable	4fjpA-5ng6A: 14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7X_F_SASF805_1 (SEPIAPTERIN REDUCTASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	LEU A1211 PHE A1112 PRO A1232 ASP A1113 ASP A1129	None	1.30A	4j7xF-5ng6A: undetectable	4j7xF-5ng6A: 13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7X_J_SASJ804_1 (SEPIAPTERIN REDUCTASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	LEU A1211 PHE A1112 PRO A1232 ASP A1113 ASP A1129	None	1.37A	4j7xJ-5ng6A: undetectable	4j7xJ-5ng6A: 13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JTP_A_ASCA802_0 (RRNA N-GLYCOSIDASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 5	TYR A 307 ILE A 304 ASN A 230 TYR A 231	None	1.01A	4jtpA-5ng6A: undetectable	4jtpA-5ng6A: 11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_B_C2FB4000_1 (DIHYDROPTEROATE SYNTHASE DHPS)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 4	LYS A 173 ASN A 602 ASP A 616 ASP A 129	None	1.49A	4o1eB-5ng6A: undetectable	4o1eB-5ng6A: 12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q15_A_HFGA803_1 (PROLINE--TRNA LIGASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	3 / 3	GLU A1225 THR A 940 HIS A 922	None	0.75A	4q15A-5ng6A: undetectable	4q15A-5ng6A: 17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q15_B_HFGB803_1 (PROLINE--TRNA LIGASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	3 / 3	GLU A1225 THR A 940 HIS A 922	None	0.79A	4q15B-5ng6A: undetectable	4q15B-5ng6A: 17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QOP_C_HQEC503_1 (CATALASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 8	PHE A 489 LEU A 536 LEU A 374 PHE A 378	None	0.87A	4qopC-5ng6A: undetectable	4qopC-5ng6A: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R3A_B_RBFB402_2 (BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	ALA A 459 LEU A 460 ILE A 542 LEU A 399 GLY A 414	None	0.81A	4r3aB-5ng6A: undetectable	4r3aB-5ng6A: 13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RET_A_DGXA1107_1 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	LEU A 399 PHE A 543 GLU A 213 PHE A 561 LEU A 386	None	1.27A	4retA-5ng6A: undetectable	4retA-5ng6A: 22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_F_377F401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 7	GLU A 213 LEU A 76 PHE A 211 TYR A 83	None	1.04A	4twdF-5ng6A: undetectable 4twdJ-5ng6A: undetectable	4twdF-5ng6A: 12.66 4twdJ-5ng6A: 12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_H_377H401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 6	TYR A1076 ASN A1009 GLU A1028 PHE A1061	None	1.24A	4twdG-5ng6A: undetectable 4twdH-5ng6A: undetectable	4twdG-5ng6A: 12.66 4twdH-5ng6A: 12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UW0_A_SAMA1506_0 (WBDD)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	GLY A1263 ALA A1259 ILE A 913 VAL A1004 ILE A1002	None	0.99A	4uw0A-5ng6A: undetectable	4uw0A-5ng6A: 16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WG0_C_CHDC102_0 (NUCLEAR RECEPTOR COACTIVATOR 2)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 7	LYS A1206 LEU A1207 LEU A1177 LEU A1178	None	0.80A	4wg0B-5ng6A: undetectable 4wg0C-5ng6A: undetectable	4wg0B-5ng6A: 2.14 4wg0C-5ng6A: 2.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WG0_L_CHDL103_0 (NUCLEAR RECEPTOR COACTIVATOR 2)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 7	LEU A1177 LEU A1178 LYS A1206 LEU A1207	None	0.81A	4wg0L-5ng6A: undetectable 4wg0M-5ng6A: undetectable	4wg0L-5ng6A: 2.14 4wg0M-5ng6A: 2.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XDR_A_ADNA402_1 (FAD:PROTEIN FMN TRANSFERASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	LEU A1264 GLY A1258 ALA A1259 ILE A 935 THR A 927	None	0.99A	4xdrA-5ng6A: undetectable	4xdrA-5ng6A: 13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YDQ_B_HFGB802_1 (PROLINE--TRNA LIGASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	3 / 3	GLU A1225 THR A 940 HIS A 922	None	0.73A	4ydqB-5ng6A: undetectable	4ydqB-5ng6A: 17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YJI_A_TYLA502_1 (ARYL ACYLAMIDASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 7	LEU A 803 GLY A1050 GLY A1049 ALA A1054	A B -1 ( 4.2A) None None None	0.73A	4yjiA-5ng6A: undetectable	4yjiA-5ng6A: 15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YSH_B_GLYB401_0 (GLYCINE OXIDASE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 6	PHE A1128 GLY A1140 TYR A1130 ALA A1138	None	1.17A	4yshB-5ng6A: undetectable	4yshB-5ng6A: 13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZB_C_ACTC401_0 (PROTON-GATED ION CHANNEL)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 7	ILE A 774 PHE A 622 VAL A 777 ILE A 640	None	0.90A	4zzbC-5ng6A: undetectable 4zzbD-5ng6A: undetectable	4zzbC-5ng6A: 14.06 4zzbD-5ng6A: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G08_A_Z80A1187_1 (FREQUENIN 2)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 6	ILE A1286 TYR A1291 PHE A1294 THR A 927	None	1.01A	5g08A-5ng6A: undetectable	5g08A-5ng6A: 10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HUA_A_FK5A201_1 (FK506-BINDING PROTEIN 1)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 11	ARG A1150 PHE A1240 PHE A1126 LEU A1211 PHE A1091	None	1.47A	5huaA-5ng6A: undetectable	5huaA-5ng6A: 5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IH0_A_ERYA404_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	ILE A1085 HIS A1261 ALA A1138 ILE A1286 MET A1268	None	1.19A	5ih0A-5ng6A: undetectable	5ih0A-5ng6A: 13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5INZ_D_DVAD15_0 (THETA DEFENSIN-2, D-PEPTIDE THETA DEFENSIN-2, L-PEPTIDE)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	3 / 3	GLY A1188 CYH A1190 CYH A1116	None	0.92A	5inzB-5ng6A: undetectable	5inzB-5ng6A: 1.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IWU_A_ERYA404_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	ILE A1085 HIS A1261 ALA A1138 ILE A1286 MET A1268	None	1.13A	5iwuA-5ng6A: undetectable	5iwuA-5ng6A: 13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LJE_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 12	LEU A1207 LEU A1178 SER A1146 ILE A1115 LEU A1095	None	1.12A	5ljeA-5ng6A: undetectable	5ljeA-5ng6A: 7.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OM3_B_DXTB501_1 (ALPHA-1-ANTICHYMOTRY PSIN)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 6	LEU A 374 SER A 375 PHE A 378 ASP A 379	None	0.67A	5om3A-5ng6A: undetectable 5om3B-5ng6A: undetectable	5om3A-5ng6A: 4.44 5om3B-5ng6A: 2.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5PHH_A_LDPA414_1 (LYSINE-SPECIFIC DEMETHYLASE 4D)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 6	GLU A 213 ALA A 216 LEU A 212 TYR A 83	None	1.14A	5phhA-5ng6A: undetectable	5phhA-5ng6A: 13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_C_PCFC1801_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 9	ILE A 65 TYR A 190 ILE A 200 LEU A 208	None	0.69A	5vkqB-5ng6A: undetectable 5vkqC-5ng6A: undetectable	5vkqB-5ng6A: 21.99 5vkqC-5ng6A: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_H_CVIH301_1 (REGULATORY PROTEIN TETR)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	4 / 8	GLN A1056 GLY A1049 ILE A 997 ASP A1042	None	1.01A	5vlmH-5ng6A: undetectable	5vlmH-5ng6A: 8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HCO_A_FY5A1003_0 (ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 2)	5ng6	CRISPR-ASSOCIATED ENDONUCLEASE CPF1 (Francisella tularensis)	5 / 11	ASN A 395 THR A 422 THR A 455 ILE A 456 VAL A 417	None	1.23A	6hcoA-5ng6A: undetectable 6hcoB-5ng6A: undetectable	6hcoA-5ng6A: 19.66 6hcoB-5ng6A: 19.66

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FM4_A_DXCA1002_0","MAJOR POLLEN ALLERGEN BET V 1-L","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"PHE A1005;VAL A1003;ILE A 944;SER A 986;LEU A1031","None;None;None;  G B  -2 ( 3.2A);None","1.27A","1fm4A-5ng6A:undetectable","1fm4A-5ng6A:7.91"],["1OIP_A_VIVA1278_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"ILE A 195;LEU A 208;ILE A 278;LEU A  66;ILE A 113","None","0.88A","1oipA-5ng6A:undetectable","1oipA-5ng6A:11.24"],["1QZF_A_FOLA605_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"VAL A1004;LEU A1035;ILE A 900;LEU A 904;TYR A1076","None","1.09A","1qzfA-5ng6A:undetectable","1qzfA-5ng6A:17.84"],["1QZF_B_FOLB609_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"VAL A1004;LEU A1035;ILE A 900;LEU A 904;TYR A1076","None","1.09A","1qzfB-5ng6A:undetectable","1qzfB-5ng6A:17.84"],["1QZF_C_FOLC613_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"VAL A1004;LEU A1035;ILE A 900;LEU A 904;TYR A1076","None","1.09A","1qzfC-5ng6A:undetectable","1qzfC-5ng6A:17.84"],["1QZF_D_FOLD617_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"VAL A1004;LEU A1035;ILE A 900;LEU A 904;TYR A1076","None","1.09A","1qzfD-5ng6A:undetectable","1qzfD-5ng6A:17.84"],["1QZF_E_FOLE621_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"VAL A1004;LEU A1035;ILE A 900;LEU A 904;TYR A1076","None","1.09A","1qzfE-5ng6A:undetectable","1qzfE-5ng6A:17.84"],["1RJD_B_SAMB802_1","CARBOXY METHYL TRANSFERASE FOR PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"ARG A1016;ASP A1253;ASP A 939;GLU A 920","None","1.27A","1rjdB-5ng6A:undetectable","1rjdB-5ng6A:12.29"],["1RJD_C_SAMC803_1","CARBOXY METHYL TRANSFERASE FOR PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"ARG A1016;ASP A1253;ASP A 939;GLU A 920","None","1.24A","1rjdC-5ng6A:undetectable","1rjdC-5ng6A:12.29"],["1YAJ_J_BEZJ5041_0","CES1 PROTEIN","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"GLY A 701;SER A 695;ILE A 750;HIS A 697","None","1.24A","1yajJ-5ng6A:undetectable","1yajJ-5ng6A:16.34"],["2CL5_B_SAMB1217_1","CATECHOL O-METHYLTRANSFERASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"SER A 322;TYR A 272;SER A  80;GLN A  77","None","0.87A","2cl5B-5ng6A:undetectable","2cl5B-5ng6A:10.52"],["2OIP_A_MTXA605_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"VAL A1004;LEU A1035;ILE A 900;LEU A 904;TYR A1076","None","1.15A","2oipA-5ng6A:undetectable","2oipA-5ng6A:17.70"],["2QE6_A_SAMA400_1","UNCHARACTERIZED PROTEIN TFU_2867","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",3,"ASN A 464;ARG A 467;ASP A 408","None","0.98A","2qe6A-5ng6A:undetectable","2qe6A-5ng6A:12.31"],["2QE6_B_SAMB400_1","UNCHARACTERIZED PROTEIN TFU_2867","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",3,"ASN A 464;ARG A 467;ASP A 408","None","0.99A","2qe6B-5ng6A:undetectable","2qe6B-5ng6A:12.31"],["2QMZ_A_LDPA501_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE;RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"GLY A 761;PHE A 741;ILE A 728;PHE A 753","None","1.03A","2qmzA-5ng6A:undetectable;2qmzB-5ng6A:undetectable","2qmzA-5ng6A:10.54;2qmzB-5ng6A:10.54"],["2V7B_B_BEZB1529_0","BENZOATE-COENZYME A LIGASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"ALA A 924;TYR A 925;ALA A1256;GLY A1258;HIS A 922","None","1.35A","2v7bB-5ng6A:undetectable","2v7bB-5ng6A:17.01"],["2VDB_A_NPSA1591_1","SERUM ALBUMIN","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"PHE A 378;LEU A 377;PHE A 565;TYR A 562","None","0.85A","2vdbA-5ng6A:undetectable","2vdbA-5ng6A:18.46"],["2W3M_B_FOLB1188_0","DIHYDROFOLATE REDUCTASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"ALA A 416;LEU A 460;PHE A 407;ASN A 481;THR A 415","None","1.22A","2w3mB-5ng6A:undetectable","2w3mB-5ng6A:8.99"],["2WEK_A_DIFA1375_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",3,"LEU A 985;TYR A 984;GLN A 987","None;None;  A B  -3 ( 3.6A)","0.65A","2wekA-5ng6A:undetectable","2wekA-5ng6A:13.99"],["2YVL_B_SAMB602_1","HYPOTHETICAL PROTEIN","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",3,"GLU A1225;ASP A1253;TYR A 925","None","0.81A","2yvlB-5ng6A:undetectable","2yvlB-5ng6A:11.07"],["2ZVJ_A_SAMA301_1","CATECHOL O-METHYLTRANSFERASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"SER A 322;TYR A 272;SER A  80;GLN A  77","None","0.91A","2zvjA-5ng6A:undetectable","2zvjA-5ng6A:10.60"],["3A9E_B_REAB1_1","RETINOIC ACID RECEPTOR ALPHA","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"PHE A 543;ILE A 478;PHE A 393;PHE A 482;LEU A 374","None","1.36A","3a9eB-5ng6A:undetectable","3a9eB-5ng6A:11.78"],["3AI9_X_SAMX501_0","UPF0217 PROTEIN MJ1640","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"ILE A 159;LEU A 142;SER A 145;GLU A 151;LEU A 152","None","1.06A","3ai9X-5ng6A:undetectable","3ai9X-5ng6A:9.94"],["3IA4_B_MTXB164_1","DIHYDROFOLATE REDUCTASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"MET A 352;LEU A 529;GLN A 532;SER A 503;ILE A 502","None","1.16A","3ia4B-5ng6A:undetectable","3ia4B-5ng6A:7.67"],["3LTW_A_HLZA300_1","ARYLAMINE N-ACETYLTRANSFERASE NAT","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"PHE A 786;TYR A 784;THR A 618;PHE A 600","None","1.31A","3ltwA-5ng6A:undetectable","3ltwA-5ng6A:11.00"],["3OWX_A_XRAA233_2","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"PHE A1126;ILE A1144;PHE A1128;PHE A1112","None","0.96A","3owxB-5ng6A:undetectable","3owxB-5ng6A:10.52"],["3R9C_A_ECLA452_1","CYTOCHROME P450 164A2","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"LEU A 830;LEU A 630;ALA A 606;ASN A 617;LEU A 783","None","1.20A","3r9cA-5ng6A:undetectable","3r9cA-5ng6A:14.08"],["3V3O_B_T1CB405_1","TETX2 PROTEIN","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"ASN A1093;GLY A1090;ALA A1079;GLY A1080;GLU A1006","None","1.22A","3v3oB-5ng6A:undetectable","3v3oB-5ng6A:14.43"],["3V3O_B_T1CB405_1","TETX2 PROTEIN","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"GLN A1296;ASN A1093;GLY A1090;GLY A1080;GLU A1006","None","1.25A","3v3oB-5ng6A:undetectable","3v3oB-5ng6A:14.43"],["3W68_D_VIVD301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",6,"LEU A 830;ILE A 657;ILE A 620;VAL A 632;LEU A 783;PHE A 600","None","1.42A","3w68D-5ng6A:undetectable","3w68D-5ng6A:10.79"],["4A6N_A_T1CA392_1","TETX2 PROTEIN","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"ASN A1093;GLY A1090;ALA A1079;GLY A1080;GLU A1006","None","1.03A","4a6nA-5ng6A:undetectable","4a6nA-5ng6A:14.74"],["4AZT_A_SAMA1472_0","METHYLTRANSFERASE WBDD","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"GLY A1263;ALA A1259;ILE A 913;VAL A1004;ILE A1002","None","1.08A","4aztA-5ng6A:undetectable","4aztA-5ng6A:17.02"],["4DM8_A_REAA501_1","RETINOIC ACID RECEPTOR BETA","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"PHE A 123;LEU A 329;PHE A 119;SER A 116;ILE A  54","None","0.89A","4dm8A-5ng6A:undetectable","4dm8A-5ng6A:11.49"],["4F93_B_SANB3004_1","U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"GLU A1175;GLU A1167;GLY A1148;SER A1149","None","1.01A","4f93B-5ng6A:undetectable","4f93B-5ng6A:21.72"],["4FJP_A_NPSA711_1","LACTOTRANSFERRIN","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"GLY A1090;PRO A1087;TYR A1260;GLY A1258","None","0.89A","4fjpA-5ng6A:undetectable","4fjpA-5ng6A:14.01"],["4J7X_F_SASF805_1","SEPIAPTERIN REDUCTASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"LEU A1211;PHE A1112;PRO A1232;ASP A1113;ASP A1129","None","1.30A","4j7xF-5ng6A:undetectable","4j7xF-5ng6A:13.04"],["4J7X_J_SASJ804_1","SEPIAPTERIN REDUCTASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"LEU A1211;PHE A1112;PRO A1232;ASP A1113;ASP A1129","None","1.37A","4j7xJ-5ng6A:undetectable","4j7xJ-5ng6A:13.04"],["4JTP_A_ASCA802_0","RRNA N-GLYCOSIDASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"TYR A 307;ILE A 304;ASN A 230;TYR A 231","None","1.01A","4jtpA-5ng6A:undetectable","4jtpA-5ng6A:11.39"],["4O1E_B_C2FB4000_1","DIHYDROPTEROATE SYNTHASE DHPS","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"LYS A 173;ASN A 602;ASP A 616;ASP A 129","None","1.49A","4o1eB-5ng6A:undetectable","4o1eB-5ng6A:12.10"],["4Q15_A_HFGA803_1","PROLINE--TRNA LIGASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",3,"GLU A1225;THR A 940;HIS A 922","None","0.75A","4q15A-5ng6A:undetectable","4q15A-5ng6A:17.11"],["4Q15_B_HFGB803_1","PROLINE--TRNA LIGASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",3,"GLU A1225;THR A 940;HIS A 922","None","0.79A","4q15B-5ng6A:undetectable","4q15B-5ng6A:17.11"],["4QOP_C_HQEC503_1","CATALASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"PHE A 489;LEU A 536;LEU A 374;PHE A 378","None","0.87A","4qopC-5ng6A:undetectable","4qopC-5ng6A:16.56"],["4R3A_B_RBFB402_2","BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"ALA A 459;LEU A 460;ILE A 542;LEU A 399;GLY A 414","None","0.81A","4r3aB-5ng6A:undetectable","4r3aB-5ng6A:13.63"],["4RET_A_DGXA1107_1","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"LEU A 399;PHE A 543;GLU A 213;PHE A 561;LEU A 386","None","1.27A","4retA-5ng6A:undetectable","4retA-5ng6A:22.06"],["4TWD_F_377F401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"GLU A 213;LEU A  76;PHE A 211;TYR A  83","None","1.04A","4twdF-5ng6A:undetectable;4twdJ-5ng6A:undetectable","4twdF-5ng6A:12.66;4twdJ-5ng6A:12.66"],["4TWD_H_377H401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"TYR A1076;ASN A1009;GLU A1028;PHE A1061","None","1.24A","4twdG-5ng6A:undetectable;4twdH-5ng6A:undetectable","4twdG-5ng6A:12.66;4twdH-5ng6A:12.66"],["4UW0_A_SAMA1506_0","WBDD","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"GLY A1263;ALA A1259;ILE A 913;VAL A1004;ILE A1002","None","0.99A","4uw0A-5ng6A:undetectable","4uw0A-5ng6A:16.30"],["4WG0_C_CHDC102_0","NUCLEAR RECEPTOR COACTIVATOR 2","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"LYS A1206;LEU A1207;LEU A1177;LEU A1178","None","0.80A","4wg0B-5ng6A:undetectable;4wg0C-5ng6A:undetectable","4wg0B-5ng6A:2.14;4wg0C-5ng6A:2.14"],["4WG0_L_CHDL103_0","NUCLEAR RECEPTOR COACTIVATOR 2","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"LEU A1177;LEU A1178;LYS A1206;LEU A1207","None","0.81A","4wg0L-5ng6A:undetectable;4wg0M-5ng6A:undetectable","4wg0L-5ng6A:2.14;4wg0M-5ng6A:2.14"],["4XDR_A_ADNA402_1","FAD:PROTEIN FMN TRANSFERASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"LEU A1264;GLY A1258;ALA A1259;ILE A 935;THR A 927","None","0.99A","4xdrA-5ng6A:undetectable","4xdrA-5ng6A:13.46"],["4YDQ_B_HFGB802_1","PROLINE--TRNA LIGASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",3,"GLU A1225;THR A 940;HIS A 922","None","0.73A","4ydqB-5ng6A:undetectable","4ydqB-5ng6A:17.30"],["4YJI_A_TYLA502_1","ARYL ACYLAMIDASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"LEU A 803;GLY A1050;GLY A1049;ALA A1054","  A B  -1 ( 4.2A);None;None;None","0.73A","4yjiA-5ng6A:undetectable","4yjiA-5ng6A:15.45"],["4YSH_B_GLYB401_0","GLYCINE OXIDASE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"PHE A1128;GLY A1140;TYR A1130;ALA A1138","None","1.17A","4yshB-5ng6A:undetectable","4yshB-5ng6A:13.21"],["4ZZB_C_ACTC401_0","PROTON-GATED ION CHANNEL","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"ILE A 774;PHE A 622;VAL A 777;ILE A 640","None","0.90A","4zzbC-5ng6A:undetectable;4zzbD-5ng6A:undetectable","4zzbC-5ng6A:14.06;4zzbD-5ng6A:14.06"],["5G08_A_Z80A1187_1","FREQUENIN 2","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"ILE A1286;TYR A1291;PHE A1294;THR A 927","None","1.01A","5g08A-5ng6A:undetectable","5g08A-5ng6A:10.28"],["5HUA_A_FK5A201_1","FK506-BINDING PROTEIN 1","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"ARG A1150;PHE A1240;PHE A1126;LEU A1211;PHE A1091","None","1.47A","5huaA-5ng6A:undetectable","5huaA-5ng6A:5.98"],["5IH0_A_ERYA404_0","MACROLIDE 2'-PHOSPHOTRANSFERASE II","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"ILE A1085;HIS A1261;ALA A1138;ILE A1286;MET A1268","None","1.19A","5ih0A-5ng6A:undetectable","5ih0A-5ng6A:13.62"],["5INZ_D_DVAD15_0","THETA DEFENSIN-2, D-PEPTIDE;THETA DEFENSIN-2, L-PEPTIDE","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",3,"GLY A1188;CYH A1190;CYH A1116","None","0.92A","5inzB-5ng6A:undetectable","5inzB-5ng6A:1.34"],["5IWU_A_ERYA404_0","MACROLIDE 2'-PHOSPHOTRANSFERASE II","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"ILE A1085;HIS A1261;ALA A1138;ILE A1286;MET A1268","None","1.13A","5iwuA-5ng6A:undetectable","5iwuA-5ng6A:13.62"],["5LJE_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"LEU A1207;LEU A1178;SER A1146;ILE A1115;LEU A1095","None","1.12A","5ljeA-5ng6A:undetectable","5ljeA-5ng6A:7.70"],["5OM3_B_DXTB501_1","ALPHA-1-ANTICHYMOTRYPSIN;ALPHA-1-ANTICHYMOTRYPSIN","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"LEU A 374;SER A 375;PHE A 378;ASP A 379","None","0.67A","5om3A-5ng6A:undetectable;5om3B-5ng6A:undetectable","5om3A-5ng6A:4.44;5om3B-5ng6A:2.76"],["5PHH_A_LDPA414_1","LYSINE-SPECIFIC DEMETHYLASE 4D","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"GLU A 213;ALA A 216;LEU A 212;TYR A  83","None","1.14A","5phhA-5ng6A:undetectable","5phhA-5ng6A:13.81"],["5VKQ_C_PCFC1801_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"ILE A  65;TYR A 190;ILE A 200;LEU A 208","None","0.69A","5vkqB-5ng6A:undetectable;5vkqC-5ng6A:undetectable","5vkqB-5ng6A:21.99;5vkqC-5ng6A:21.99"],["5VLM_H_CVIH301_1","REGULATORY PROTEIN TETR","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",4,"GLN A1056;GLY A1049;ILE A 997;ASP A1042","None","1.01A","5vlmH-5ng6A:undetectable","5vlmH-5ng6A:8.49"],["6HCO_A_FY5A1003_0","ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 2","5ng6","CRISPR-ASSOCIATED ENDONUCLEASE CPF1","Francisella tularensis",5,"ASN A 395;THR A 422;THR A 455;ILE A 456;VAL A 417","None","1.23A","6hcoA-5ng6A:undetectable;6hcoB-5ng6A:undetectable","6hcoA-5ng6A:19.66;6hcoB-5ng6A:19.66"]]