SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ngd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 5ngd PORTAL PROTEIN
(Thermus
virus
P74-26) 		4 / 7 ARG A 430
ALA A 100
PRO A  88
ALA A  99
 None
 1.04A 2ejfA-5ngdA:
undetectable		 2ejfA-5ngdA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 5ngd PORTAL PROTEIN
(Thermus
virus
P74-26) 		4 / 5 GLN A 105
PHE A 101
TRP A 365
GLY A 146
 None
 1.20A 2qmzA-5ngdA:
undetectable
2qmzB-5ngdA:
undetectable		 2qmzA-5ngdA:
18.03
2qmzB-5ngdA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 5ngd PORTAL PROTEIN
(Thermus
virus
P74-26) 		5 / 12 LEU A 312
ILE A  75
ALA A 218
VAL A 219
PHE A  76
 None
 1.38A 2qo4A-5ngdA:
undetectable		 2qo4A-5ngdA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 5ngd PORTAL PROTEIN
(Thermus
virus
P74-26) 		5 / 9 ALA A  71
TYR A  74
GLY A  77
ILE A  79
ILE A 341
 None
 1.01A 4eatB-5ngdA:
undetectable		 4eatB-5ngdA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 5ngd PORTAL PROTEIN
(Thermus
virus
P74-26) 		4 / 7 ALA A 351
VAL A 352
TYR A 125
ALA A 128
 None
 0.71A 4g77A-5ngdA:
undetectable		 4g77A-5ngdA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5ngd PORTAL PROTEIN
(Thermus
virus
P74-26) 		5 / 12 LEU A 344
SER A 213
ALA A 134
ALA A 128
GLY A 132
 None
 1.15A 5tzoB-5ngdA:
undetectable		 5tzoB-5ngdA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 5ngd PORTAL PROTEIN
(Thermus
virus
P74-26) 		3 / 3 TYR A 131
HIS A  60
MET A  62
 None
 1.24A 6af6A-5ngdA:
1.1		 6af6A-5ngdA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA814_0
(UNCHARACTERIZED
PROTEIN)		 5ngd PORTAL PROTEIN
(Thermus
virus
P74-26) 		4 / 5 TYR A  74
ASN A  70
THR A 318
LEU A 321
 None
 1.26A 6d8pA-5ngdA:
undetectable		 6d8pA-5ngdA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5ngd PORTAL PROTEIN
(Thermus
virus
P74-26) 		4 / 6 MET A  62
GLY A  66
ALA A  71
LEU A  72
 None
 1.02A 6fosA-5ngdA:
undetectable		 6fosA-5ngdA:
11.03