SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ngj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		5 / 9 VAL A 157
GLY A 165
ALA A 310
ILE A  76
THR A 209
 None
 1.24A 1gtnL-5ngjA:
undetectable
1gtnM-5ngjA:
undetectable		 1gtnL-5ngjA:
undetectable
1gtnM-5ngjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		3 / 3 ASP A  91
LEU A  98
LEU A  94
 None
 0.68A 1ikeA-5ngjA:
undetectable		 1ikeA-5ngjA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		3 / 3 ASP A  91
LEU A  98
LEU A  94
 None
 0.65A 1np1B-5ngjA:
undetectable		 1np1B-5ngjA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		3 / 3 ASP A 193
TYR A 196
GLU A  27
 None
 0.74A 1vm1A-5ngjA:
undetectable		 1vm1A-5ngjA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		4 / 8 GLY A  37
GLU A  69
ALA A  68
ILE A 147
 None
 0.78A 2dtjA-5ngjA:
undetectable
2dtjB-5ngjA:
undetectable		 2dtjA-5ngjA:
undetectable
2dtjB-5ngjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		5 / 12 PHE A 353
TYR A  79
ALA A 310
GLY A 165
TYR A  92
 None
 1.21A 2igtC-5ngjA:
undetectable		 2igtC-5ngjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		4 / 7 GLY A 111
ALA A 112
LEU A 106
SER A 100
 CL  A 502 (-3.4A)
None
None
CL  A 502 (-4.2A)
 0.84A 2wekB-5ngjA:
undetectable		 2wekB-5ngjA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		4 / 7 SER A 273
ALA A 267
VAL A 334
ILE A 213
 None
 0.69A 3a2qA-5ngjA:
undetectable		 3a2qA-5ngjA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		5 / 11 ASP A 374
THR A 360
THR A 361
ASN A 364
GLY A 371
 None
 0.99A 3sfuC-5ngjA:
undetectable		 3sfuC-5ngjA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		5 / 11 THR A 360
THR A 361
ASN A 364
GLY A 371
ASP A 370
 None
 1.41A 3sfuC-5ngjA:
undetectable		 3sfuC-5ngjA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		3 / 3 TRP A  95
TRP A 169
THR A  74
 None
 1.30A 4bboB-5ngjA:
undetectable		 4bboB-5ngjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		4 / 8 ASP A  91
VAL A 167
PHE A 353
LEU A 351
 None
 1.09A 4f8hB-5ngjA:
undetectable
4f8hC-5ngjA:
undetectable		 4f8hB-5ngjA:
14.75
4f8hC-5ngjA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		4 / 8 VAL A 167
PHE A 353
LEU A 351
ASP A  91
 None
 1.10A 4f8hA-5ngjA:
undetectable
4f8hE-5ngjA:
undetectable		 4f8hA-5ngjA:
14.75
4f8hE-5ngjA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		5 / 12 PHE A 255
GLY A 257
GLU A 260
ASN A 234
ILE A 237
 None
 1.16A 4u95B-5ngjA:
undetectable		 4u95B-5ngjA:
6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		4 / 4 LEU A 297
TYR A 303
PRO A 225
ILE A 224
 None
 1.24A 5esgA-5ngjA:
undetectable		 5esgA-5ngjA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		5 / 9 GLY A 101
LEU A 131
GLY A 111
PHE A  72
ILE A  28
 None
CL  A 501 (-4.2A)
CL  A 502 (-3.4A)
None
None
 0.99A 5vkqC-5ngjA:
undetectable
5vkqD-5ngjA:
undetectable		 5vkqC-5ngjA:
undetectable
5vkqD-5ngjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_H_BEZH201_0
(NS3 PROTEASE)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		4 / 5 HIS A  96
SER A 100
TYR A 128
GLY A 101
 None
CL  A 502 (-4.2A)
None
None
 0.96A 5yodH-5ngjA:
undetectable		 5yodH-5ngjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5ngj TAIL TUBE PROTEIN
(Escherichia
virus
T5) 		5 / 12 LEU A 287
SER A 264
THR A 332
LEU A 269
TYR A 280
 None
 1.15A 6djzC-5ngjA:
undetectable		 6djzC-5ngjA:
undetectable