SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ngk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  68
THR A  69
PRO A  67
 None
 0.83A 1a7yA-5ngkA:
undetectable		 1a7yA-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  69
PRO A  67
THR A  68
 None
 0.87A 1a7yB-5ngkA:
undetectable		 1a7yB-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A  88
ILE A 161
MET A  99
LEU A 379
ILE A 410
 None
 1.06A 1bsxA-5ngkA:
undetectable		 1bsxA-5ngkA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A  88
ILE A 161
MET A  99
LEU A 379
ILE A 410
 None
 1.06A 1bsxB-5ngkA:
undetectable		 1bsxB-5ngkA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 THR A  89
GLU A 339
THR A 340
HIS A 415
 None
 1.31A 1d4fA-5ngkA:
undetectable		 1d4fA-5ngkA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 THR A  89
GLU A 339
THR A 340
HIS A 415
 None
 1.27A 1d4fC-5ngkA:
undetectable		 1d4fC-5ngkA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 THR A  89
GLU A 339
THR A 340
HIS A 415
 None
 1.28A 1d4fD-5ngkA:
undetectable		 1d4fD-5ngkA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ASP A 131
THR A  89
ILE A  88
THR A 338
ILE A 375
 None
 1.39A 1hzeA-5ngkA:
undetectable
1hzeB-5ngkA:
undetectable		 1hzeA-5ngkA:
10.77
1hzeB-5ngkA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 THR A 338
ILE A 375
ASP A 131
THR A  89
ILE A  88
 None
 1.40A 1hzeA-5ngkA:
undetectable
1hzeB-5ngkA:
undetectable		 1hzeA-5ngkA:
10.77
1hzeB-5ngkA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  69
PRO A  67
THR A  68
 None
 0.87A 1i3wE-5ngkA:
undetectable		 1i3wE-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  68
THR A  69
PRO A  67
 None
 0.83A 1i3wE-5ngkA:
undetectable		 1i3wE-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  68
THR A  69
PRO A  67
 None
 0.81A 1i3wF-5ngkA:
undetectable		 1i3wF-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  69
PRO A  67
THR A  68
 None
 0.85A 1i3wG-5ngkA:
undetectable		 1i3wG-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  68
THR A  69
PRO A  67
 None
 0.84A 1i3wG-5ngkA:
undetectable		 1i3wG-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  68
THR A  69
PRO A  67
 None
 0.85A 1i3wH-5ngkA:
undetectable		 1i3wH-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 PHE A 279
ALA A 278
LEU A 263
ALA A 262
LEU A 308
 None
 1.07A 1jinA-5ngkA:
undetectable		 1jinA-5ngkA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASN A 413
ILE A 342
GLY A 343
GLY A 386
 None
 0.73A 1me7A-5ngkA:
7.5		 1me7A-5ngkA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  69
PRO A  67
THR A  68
 None
 0.81A 1mnvD-5ngkA:
undetectable		 1mnvD-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  68
THR A  69
PRO A  67
 None
 0.77A 1mnvD-5ngkA:
undetectable		 1mnvD-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  68
THR A  69
PRO A  67
 None
 0.81A 1qfiA-5ngkA:
undetectable		 1qfiA-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A 336
GLU A 334
ILE A 175
TYR A 122
 None
 1.04A 1qvtA-5ngkA:
undetectable		 1qvtA-5ngkA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  69
PRO A  67
THR A  68
 None
 0.78A 1unjF-5ngkA:
undetectable		 1unjF-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  68
THR A  69
PRO A  67
 None
 0.81A 1unjF-5ngkA:
undetectable		 1unjF-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  69
PRO A  67
THR A  68
 None
 0.84A 1unjR-5ngkA:
undetectable		 1unjR-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  68
THR A  69
PRO A  67
 None
 0.83A 1unjR-5ngkA:
undetectable		 1unjR-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A  37
THR A  36
ASP A  38
ASN A  58
 None
 0.92A 2g70A-5ngkA:
undetectable		 2g70A-5ngkA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A  37
THR A  36
ASP A  38
ASN A  58
 None
 0.84A 2g70B-5ngkA:
undetectable		 2g70B-5ngkA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLY A 398
ILE A 418
SER A 414
ALA A 363
VAL A 376
 None
 1.10A 2nnhA-5ngkA:
undetectable		 2nnhA-5ngkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		8 / 12 ASP A 131
TRP A 179
ASN A 237
GLU A 238
HIS A 314
TYR A 316
GLU A 339
TRP A 377
 None
 0.38A 2v3dA-5ngkA:
46.2		 2v3dA-5ngkA:
27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		7 / 11 ASP A 131
TRP A 179
ASN A 237
GLU A 238
TYR A 316
GLU A 339
TRP A 377
 None
 0.38A 2v3dB-5ngkA:
46.1		 2v3dB-5ngkA:
27.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 ILE A 158
LEU A 108
LEU A 379
ILE A  88
ILE A 172
 None
 1.03A 2w9sA-5ngkA:
undetectable		 2w9sA-5ngkA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 ILE A 158
LEU A 108
LEU A 379
ILE A  88
ILE A 172
 None
 1.02A 2w9sB-5ngkA:
undetectable		 2w9sB-5ngkA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A  91
CYH A  93
ILE A  88
SER A 130
 None
 1.15A 2xz5A-5ngkA:
undetectable
2xz5B-5ngkA:
undetectable		 2xz5A-5ngkA:
19.15
2xz5B-5ngkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 SER A 446
ASN A 368
ARG A 432
PHE A 337
GLY A 373
 None
 1.49A 3a27A-5ngkA:
undetectable		 3a27A-5ngkA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 THR A  89
GLU A 339
THR A 340
HIS A 415
 None
 1.39A 3glqA-5ngkA:
undetectable		 3glqA-5ngkA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 THR A  89
GLU A 339
THR A 340
HIS A 415
 None
 1.28A 3glqB-5ngkA:
undetectable		 3glqB-5ngkA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 VAL A 482
MET A 356
ILE A 460
ILE A 443
 None
 0.94A 3hgxA-5ngkA:
undetectable		 3hgxA-5ngkA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 THR A  89
GLU A 339
THR A 340
HIS A 415
 None
 1.22A 3n58A-5ngkA:
undetectable		 3n58A-5ngkA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A 427
ARG A 491
ASP A 116
 None
 1.21A 3o7wA-5ngkA:
undetectable		 3o7wA-5ngkA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A  75
ALA A 434
THR A 435
ASN A  73
LEU A  72
 None
 0.98A 3r9cA-5ngkA:
undetectable		 3r9cA-5ngkA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 HIS A 281
SER A 341
GLU A 339
 None
 0.85A 3s8pA-5ngkA:
undetectable		 3s8pA-5ngkA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 PHE A 457
ALA A 447
THR A 435
LEU A 364
 None
 1.20A 3t3zC-5ngkA:
undetectable		 3t3zC-5ngkA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WFA_B_EDTB802_0
(ALPHA-GLUCOSIDASE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A 316
ASP A 286
ASN A 284
TYR A 283
 None
 1.03A 3wfaA-5ngkA:
5.7
3wfaB-5ngkA:
6.5		 3wfaA-5ngkA:
23.05
3wfaB-5ngkA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 VAL A 174
TYR A 277
ILE A 125
ILE A 375
 None
 1.05A 4afgD-5ngkA:
undetectable
4afgE-5ngkA:
undetectable		 4afgD-5ngkA:
18.96
4afgE-5ngkA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A  69
PRO A  67
THR A  68
 None
 0.77A 4hivD-5ngkA:
undetectable		 4hivD-5ngkA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 VAL A 400
TYR A 416
LEU A 108
LEU A  96
 None
 1.10A 4jtrA-5ngkA:
5.7		 4jtrA-5ngkA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A 263
GLY A 264
ILE A 220
LYS A 218
 None
 1.05A 4ma8C-5ngkA:
undetectable		 4ma8C-5ngkA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 THR A  92
THR A  89
THR A 340
HIS A 415
 None
 1.35A 4pgfB-5ngkA:
undetectable		 4pgfB-5ngkA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 SER A 489
THR A  44
SER A 486
ASP A  51
 None
 1.31A 4qb9D-5ngkA:
undetectable		 4qb9D-5ngkA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A 376
LEU A  96
ALA A 399
LEU A 381
GLY A  90
 None
 1.30A 4qckA-5ngkA:
undetectable		 4qckA-5ngkA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 341
TYR A 316
ASP A 131
 None
 0.80A 4rp8C-5ngkA:
undetectable		 4rp8C-5ngkA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 381
SER A 341
GLU A 339
GLU A 153
GLY A 128
 None
 1.32A 5f9zB-5ngkA:
undetectable		 5f9zB-5ngkA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A  90
SER A 126
THR A  92
ASN A  95
LEU A 134
 None
 1.16A 5kocB-5ngkA:
undetectable		 5kocB-5ngkA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 5ngk GLUCOSYLCERAMIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 LEU A 263
ALA A 213
PHE A 216
VAL A 233
ILE A 276
 None
 1.20A 5om2A-5ngkA:
undetectable
5om2B-5ngkA:
undetectable		 5om2A-5ngkA:
10.42
5om2B-5ngkA:
5.22