SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ngw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		4 / 6 ASP A 349
GLY A 350
THR A 352
PRO A 353
 None
 0.80A 1n4fA-5ngwA:
undetectable		 1n4fA-5ngwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		4 / 7 LEU A 185
ILE A 127
ALA A 187
PRO A 132
 None
 0.94A 1oniB-5ngwA:
undetectable
1oniC-5ngwA:
undetectable		 1oniB-5ngwA:
undetectable
1oniC-5ngwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		3 / 3 GLU A 341
ASN A 332
TRP A  42
 None
 1.31A 1r15C-5ngwA:
undetectable		 1r15C-5ngwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		3 / 3 GLU A 341
ASN A 332
TRP A  42
 None
 1.29A 1r15E-5ngwA:
undetectable		 1r15E-5ngwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		3 / 3 PHE A 194
TYR A 120
TYR A 122
 None
 0.75A 1x70B-5ngwA:
undetectable		 1x70B-5ngwA:
8.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		4 / 7 TRP A 264
PRO A 221
TYR A 241
THR A  16
 None
BR  A 402 (-4.8A)
None
None
 1.10A 2aouB-5ngwA:
2.1		 2aouB-5ngwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		4 / 7 SER A 323
TYR A 211
VAL A 176
TYR A 169
 None
 1.23A 2x45C-5ngwA:
undetectable		 2x45C-5ngwA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		4 / 7 SER A 323
TYR A 211
VAL A 176
TYR A 169
 None
 1.17A 3bu1A-5ngwA:
undetectable		 3bu1A-5ngwA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		3 / 3 ARG A 228
PRO A 217
PHE A 229
 None
 0.99A 3thrC-5ngwA:
undetectable		 3thrC-5ngwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		4 / 6 GLU A 209
GLY A 207
LEU A 210
GLU A 163
 None
 1.16A 3w9tF-5ngwA:
undetectable		 3w9tF-5ngwA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		4 / 7 PHE A 229
ILE A 281
TYR A 280
HIS A 238
 None
 1.18A 4g5jA-5ngwA:
undetectable		 4g5jA-5ngwA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		5 / 12 ILE A 213
ALA A 315
ALA A 316
VAL A 320
GLY A 262
 None
 1.19A 5igpA-5ngwA:
undetectable		 5igpA-5ngwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		4 / 6 GLU A 341
THR A  56
TYR A  55
TYR A  46
 None
 1.32A 5lrbA-5ngwA:
undetectable		 5lrbA-5ngwA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5ngw OPGH99A
(Ochrovirga
pacifica) 		3 / 3 SER A 267
HIS A 238
TYR A 241
 None
 0.96A 5y2tA-5ngwA:
undetectable		 5y2tA-5ngwA:
undetectable