SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nil'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 8 THR J 389
GLY J 374
GLY J 381
PHE J 377
 None
 0.74A 1d0vA-5nilJ:
undetectable		 1d0vA-5nilJ:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 12 GLY J 278
GLY J 583
GLY J 584
LEU J 274
LEU J 273
 None
 0.95A 1eizA-5nilJ:
undetectable		 1eizA-5nilJ:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 12 GLY J 278
GLY J 583
GLY J 584
LEU J 274
LEU J 273
 None
 0.92A 1ej0A-5nilJ:
undetectable		 1ej0A-5nilJ:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 8 THR J 389
GLY J 374
GLY J 381
PHE J 377
 None
 0.78A 1jhaA-5nilJ:
undetectable		 1jhaA-5nilJ:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.00A 1t85A-5nilJ:
undetectable		 1t85A-5nilJ:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.03A 1t87A-5nilJ:
undetectable		 1t87A-5nilJ:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.03A 1yrcA-5nilJ:
undetectable		 1yrcA-5nilJ:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.02A 1yrdA-5nilJ:
undetectable		 1yrdA-5nilJ:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 12 GLY J 219
ILE J 214
ILE J  39
ILE J  53
ILE J 221
 None
 0.92A 2b60A-5nilJ:
3.9		 2b60A-5nilJ:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 12 GLY J  41
ARG J 217
ARG J 223
ASP J 218
ALA J  42
 None
 1.06A 2br4E-5nilJ:
undetectable		 2br4E-5nilJ:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.05A 2cppA-5nilJ:
undetectable		 2cppA-5nilJ:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.03A 2feuB-5nilJ:
undetectable		 2feuB-5nilJ:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		3 / 3 ASP J 364
ARG J 357
ARG J 359
 None
 0.91A 2j9dA-5nilJ:
3.1
2j9dC-5nilJ:
2.9		 2j9dA-5nilJ:
11.67
2j9dC-5nilJ:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 5 LEU J 134
ALA J 156
ILE J 155
SER J 154
 None
 0.92A 2othA-5nilJ:
undetectable		 2othA-5nilJ:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 12 ILE J 279
ALA J 576
ASN J 268
THR J 272
LEU J 265
 None
 1.09A 2rlcA-5nilJ:
undetectable		 2rlcA-5nilJ:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 6 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.04A 2zawA-5nilJ:
undetectable		 2zawA-5nilJ:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.02A 2zaxA-5nilJ:
undetectable		 2zaxA-5nilJ:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 6 PHE J 413
THR J 408
LEU J 404
VAL J 433
 None
 1.08A 2zuiA-5nilJ:
undetectable		 2zuiA-5nilJ:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.03A 2zwtA-5nilJ:
undetectable		 2zwtA-5nilJ:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.03A 2zwuA-5nilJ:
undetectable		 2zwuA-5nilJ:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 12 ILE J 214
ILE J  27
SER J  28
LEU J  54
ILE J  39
 None
 1.17A 3cd2A-5nilJ:
undetectable		 3cd2A-5nilJ:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 9 ALA J 529
VAL J 290
GLY J 282
ILE J 281
ILE J 289
 None
 0.97A 3ekvB-5nilJ:
3.1		 3ekvB-5nilJ:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.03A 3fwfB-5nilJ:
undetectable		 3fwfB-5nilJ:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 6 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.02A 3fwgA-5nilJ:
undetectable		 3fwgA-5nilJ:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.02A 3fwgB-5nilJ:
undetectable		 3fwgB-5nilJ:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.05A 3fwjA-5nilJ:
undetectable		 3fwjA-5nilJ:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 11 ALA J 529
VAL J 290
GLY J 282
ILE J 281
ILE J 289
 None
 1.01A 3lzvB-5nilJ:
3.2		 3lzvB-5nilJ:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 10 ALA J 529
VAL J 290
GLY J 282
ILE J 281
ILE J 289
 None
 0.98A 3nu6A-5nilJ:
3.6		 3nu6A-5nilJ:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 10 ALA J 529
VAL J 290
GLY J 282
ILE J 281
ILE J 289
 None
 1.01A 3nujA-5nilJ:
3.9		 3nujA-5nilJ:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 8 VAL J 345
VAL J 314
ILE J 339
GLN J 340
 None
 0.96A 3remA-5nilJ:
5.1		 3remA-5nilJ:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 8 VAL J 345
VAL J 314
ILE J 339
GLN J 340
 None
 0.93A 3remB-5nilJ:
5.1		 3remB-5nilJ:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		3 / 3 GLY J 374
THR J 389
ASN J 378
 None
 0.72A 3v4tD-5nilJ:
0.9		 3v4tD-5nilJ:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 6 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.04A 3wrhE-5nilJ:
undetectable		 3wrhE-5nilJ:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.02A 3wrjA-5nilJ:
undetectable		 3wrjA-5nilJ:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 6 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.02A 3wrjE-5nilJ:
undetectable		 3wrjE-5nilJ:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.03A 3wrlE-5nilJ:
undetectable		 3wrlE-5nilJ:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.03A 3wrmA-5nilJ:
undetectable		 3wrmA-5nilJ:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 0.99A 3wrmF-5nilJ:
undetectable		 3wrmF-5nilJ:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 PHE J 480
VAL J 476
ILE J 312
ASN J 310
 None
 1.10A 4a97E-5nilJ:
2.0		 4a97E-5nilJ:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 6 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.03A 4ek1A-5nilJ:
undetectable		 4ek1A-5nilJ:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 6 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.00A 4g3rA-5nilJ:
undetectable		 4g3rA-5nilJ:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 6 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 0.99A 4g3rB-5nilJ:
undetectable		 4g3rB-5nilJ:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 6 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.01A 4kkyX-5nilJ:
undetectable		 4kkyX-5nilJ:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 6 LEU J 358
VAL J 365
VAL J 449
ASP J 405
 None
 1.02A 4l4cA-5nilJ:
undetectable		 4l4cA-5nilJ:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 12 VAL J 463
VAL J 452
LEU J 404
LEU J 454
LEU J 356
 None
 1.06A 4m11B-5nilJ:
undetectable		 4m11B-5nilJ:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 12 VAL J 463
VAL J 452
LEU J 404
LEU J 454
LEU J 356
 None
 1.05A 4m11C-5nilJ:
undetectable		 4m11C-5nilJ:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 12 VAL J 463
VAL J 452
LEU J 404
LEU J 454
LEU J 356
 None
 1.06A 4m11D-5nilJ:
undetectable		 4m11D-5nilJ:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 9 VAL J 197
ALA J 158
ARG J 193
ARG J 131
ILE J  91
 None
 1.42A 4oknB-5nilJ:
undetectable		 4oknB-5nilJ:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		4 / 7 THR J 458
TYR J 456
PRO J 455
SER J 460
 None
 1.36A 5b6iA-5nilJ:
undetectable		 5b6iA-5nilJ:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		5 / 12 GLY J 374
GLY J 435
ASP J 418
VAL J 419
ILE J 434
 None
 1.01A 5njvD-5nilJ:
undetectable		 5njvD-5nilJ:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		3 / 3 GLY J 461
VAL J 426
MET J 429
 None
 0.62A 5ycpA-5nilJ:
undetectable		 5ycpA-5nilJ:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 5nil MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB
(Escherichia
coli) 		3 / 3 ASP J 334
SER J 457
SER J 460
 None
 0.83A 6mxtA-5nilJ:
3.0		 6mxtA-5nilJ:
22.74