SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nit'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 VAL A 285
ILE A  49
GLY A  26
ALA A  25
LEU A 287
 None
None
FAD  A 601 (-3.5A)
None
None
 0.89A 1eqhA-5nitA:
undetectable		 1eqhA-5nitA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 VAL A 285
ILE A  49
GLY A  26
ALA A  25
LEU A 287
 None
None
FAD  A 601 (-3.5A)
None
None
 0.85A 1eqhB-5nitA:
undetectable		 1eqhB-5nitA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 4 GLY A 346
ASP A 416
GLY A 108
THR A 112
 None
DIO  A 618 (-3.8A)
FAD  A 601 (-3.3A)
None
 1.07A 1hxbB-5nitA:
undetectable		 1hxbB-5nitA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 6 PRO A 508
PHE A 455
GLU A 458
GLN A 464
 None
 1.45A 1l2iB-5nitA:
undetectable		 1l2iB-5nitA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 10 GLU A 412
LEU A 428
HIS A 210
PRO A 209
ALA A 352
 None
 1.31A 1mjqC-5nitA:
undetectable
1mjqD-5nitA:
undetectable		 1mjqC-5nitA:
11.50
1mjqD-5nitA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 ILE A 551
GLY A 530
VAL A 532
ASP A 533
ALA A 391
 None
None
None
None
NAG  A 609 (-3.5A)
 1.34A 1nbhC-5nitA:
undetectable		 1nbhC-5nitA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 LEU A  47
VAL A 250
ILE A 297
SER A 301
LEU A 544
 None
FAD  A 601 (-4.0A)
None
None
None
 1.06A 1s19A-5nitA:
undetectable		 1s19A-5nitA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 10 ILE A 438
VAL A 322
VAL A 436
GLY A 323
LEU A 309
 None
 1.44A 1s1uA-5nitA:
undetectable		 1s1uA-5nitA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		3 / 3 LYS A 570
ASP A 120
ASN A 135
 None
 0.71A 2bm9A-5nitA:
3.0		 2bm9A-5nitA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		3 / 3 SER A  96
ASP A 548
CYH A 521
 FAD  A 601 ( 4.1A)
FAD  A 601 (-4.5A)
None
 1.07A 2br4E-5nitA:
undetectable		 2br4E-5nitA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		3 / 3 LEU A 373
ASN A 370
ARG A 400
 None
 0.94A 2qhfA-5nitA:
undetectable		 2qhfA-5nitA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 ILE A   4
LEU A 233
ALA A  35
VAL A  46
THR A 246
 None
 1.20A 2qo6A-5nitA:
undetectable		 2qo6A-5nitA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 THR A 468
ALA A 465
LEU A 461
LEU A 494
PRO A 508
 None
 1.04A 2qxsA-5nitA:
undetectable		 2qxsA-5nitA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 THR A 468
ALA A 465
LEU A 461
LEU A 494
PRO A 508
 None
 1.04A 2qxsB-5nitA:
undetectable		 2qxsB-5nitA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 9 ALA A 418
SER A 183
GLY A 342
SER A 422
ALA A 421
 None
None
DIO  A 620 ( 4.9A)
None
None
 1.28A 2vh3A-5nitA:
undetectable		 2vh3A-5nitA:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 THR A  39
VAL A  48
GLU A  50
THR A 246
ILE A   4
 None
None
FAD  A 601 (-2.7A)
None
None
 1.22A 2vn0A-5nitA:
undetectable		 2vn0A-5nitA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 5 ARG A 383
ALA A 380
GLU A 379
TRP A 376
 None
 1.50A 2xrzA-5nitA:
undetectable		 2xrzA-5nitA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 GLY A 304
GLY A 302
ILE A 308
SER A 307
LEU A 324
 None
 1.06A 2zbpA-5nitA:
undetectable		 2zbpA-5nitA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 GLY A 530
ALA A 391
ASP A 533
VAL A 538
ASN A 325
 None
NAG  A 609 (-3.5A)
None
None
None
 1.05A 2zulA-5nitA:
3.1		 2zulA-5nitA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 PHE A 126
GLY A 530
ALA A 391
ASP A 533
VAL A 538
 None
None
NAG  A 609 (-3.5A)
None
None
 0.99A 2zulA-5nitA:
3.1		 2zulA-5nitA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 GLY A 530
ALA A 391
ASP A 533
VAL A 538
ASN A 325
 None
NAG  A 609 (-3.5A)
None
None
None
 1.11A 3dmfA-5nitA:
undetectable		 3dmfA-5nitA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 PHE A 126
GLY A 530
ALA A 391
ASP A 533
VAL A 538
 None
None
NAG  A 609 (-3.5A)
None
None
 1.03A 3dmfA-5nitA:
undetectable		 3dmfA-5nitA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 GLY A 530
ALA A 391
ASP A 533
VAL A 538
ASN A 325
 None
NAG  A 609 (-3.5A)
None
None
None
 1.10A 3dmhA-5nitA:
undetectable		 3dmhA-5nitA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 PHE A 126
GLY A 530
ALA A 391
ASP A 533
VAL A 538
 None
None
NAG  A 609 (-3.5A)
None
None
 1.03A 3dmhA-5nitA:
undetectable		 3dmhA-5nitA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 GLY A 290
ALA A 289
ILE A  49
VAL A  48
ILE A 297
 FAD  A 601 (-3.7A)
FAD  A 601 (-3.6A)
None
None
None
 0.83A 3ekqA-5nitA:
undetectable		 3ekqA-5nitA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_B_TOPB200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 ALA A 352
LEU A 470
GLU A 356
VAL A 198
THR A 353
 None
 1.09A 3fl9B-5nitA:
undetectable		 3fl9B-5nitA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 10 ALA A 352
LEU A 470
GLU A 356
VAL A 198
THR A 353
 None
 1.05A 3fl9E-5nitA:
undetectable		 3fl9E-5nitA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_G_TOPG200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 ALA A 352
LEU A 470
GLU A 356
VAL A 198
THR A 353
 None
 1.06A 3fl9G-5nitA:
undetectable		 3fl9G-5nitA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 7 GLN A 395
GLY A 385
THR A 389
ALA A 380
 None
 0.70A 3fpjB-5nitA:
4.0		 3fpjB-5nitA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 7 GLY A  26
THR A  34
GLU A  50
ALA A 288
 FAD  A 601 (-3.5A)
None
FAD  A 601 (-2.7A)
None
 0.75A 3fpjB-5nitA:
4.0		 3fpjB-5nitA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 ARG A 545
GLN A 542
VAL A 532
LEU A 298
ILE A 303
 None
 1.10A 3gwxB-5nitA:
undetectable		 3gwxB-5nitA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 4 GLY A 346
ASP A 416
GLY A 108
THR A 112
 None
DIO  A 618 (-3.8A)
FAD  A 601 (-3.3A)
None
 1.10A 3k4vC-5nitA:
undetectable		 3k4vC-5nitA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		6 / 11 LEU A 298
GLY A 290
ALA A 289
VAL A 250
ILE A 547
ILE A 297
 None
FAD  A 601 (-3.7A)
FAD  A 601 (-3.6A)
FAD  A 601 (-4.0A)
None
None
 1.39A 3nu3B-5nitA:
undetectable		 3nu3B-5nitA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 6 GLY A 384
GLY A 385
LEU A 326
HIS A 437
 None
 0.81A 3o9mB-5nitA:
undetectable		 3o9mB-5nitA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		3 / 3 ALA A 409
VAL A 408
GLN A 118
 None
 0.60A 3of4B-5nitA:
2.0		 3of4B-5nitA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 LEU A  47
GLY A  26
ALA A  25
VAL A 279
ILE A  23
 None
FAD  A 601 (-3.5A)
None
None
None
 1.02A 3oxcB-5nitA:
undetectable		 3oxcB-5nitA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		6 / 12 GLY A  27
GLY A 101
ALA A 289
ALA A  25
LEU A 233
TRP A 232
 FAD  A 601 ( 4.8A)
None
FAD  A 601 (-3.6A)
None
None
None
 1.40A 3p2kA-5nitA:
4.3		 3p2kA-5nitA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		6 / 12 GLY A  27
GLY A 101
ALA A 289
ALA A  25
LEU A 233
TRP A 232
 FAD  A 601 ( 4.8A)
None
FAD  A 601 (-3.6A)
None
None
None
 1.39A 3p2kC-5nitA:
5.5		 3p2kC-5nitA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_0
(16S RRNA METHYLASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		6 / 12 GLY A  27
GLY A 101
ALA A 289
ALA A  25
LEU A 233
TRP A 232
 FAD  A 601 ( 4.8A)
None
FAD  A 601 (-3.6A)
None
None
None
 1.32A 3p2kD-5nitA:
4.2		 3p2kD-5nitA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 LEU A  47
GLY A  26
VAL A 285
GLY A 251
ILE A  23
 None
FAD  A 601 (-3.5A)
None
None
None
 0.89A 3tkgD-5nitA:
undetectable		 3tkgD-5nitA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 GLY A 304
GLY A 302
ILE A 308
ILE A 314
LEU A 324
 None
 0.96A 3uj7B-5nitA:
undetectable		 3uj7B-5nitA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD6_0
(VAL-GRAMICIDIN A)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 4 TRP A 133
TRP A 122
ALA A 117
VAL A 119
 DIO  A 610 ( 3.9A)
None
None
DIO  A 610 ( 4.9A)
 1.28A 3zq8C-5nitA:
undetectable
3zq8D-5nitA:
undetectable		 3zq8C-5nitA:
2.74
3zq8D-5nitA:
2.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 11 TYR A 450
TYR A  80
GLU A  50
SER A  51
GLY A  26
 None
None
FAD  A 601 (-2.7A)
FAD  A 601 (-3.0A)
FAD  A 601 (-3.5A)
 1.31A 4ey7A-5nitA:
undetectable		 4ey7A-5nitA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 11 TYR A 450
TYR A  80
GLU A  50
SER A  51
GLY A  26
 None
None
FAD  A 601 (-2.7A)
FAD  A 601 (-3.0A)
FAD  A 601 (-3.5A)
 1.33A 4ey7B-5nitA:
undetectable		 4ey7B-5nitA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 GLY A  99
GLY A 102
GLY A 101
THR A  34
LEU A  32
 FAD  A 601 (-4.6A)
FAD  A 601 (-3.0A)
None
None
None
 0.92A 4o33A-5nitA:
undetectable		 4o33A-5nitA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		3 / 3 PRO A 311
LEU A 312
HIS A 447
 None
 0.65A 4pevA-5nitA:
3.7		 4pevA-5nitA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 11 THR A  33
THR A  34
GLY A  28
ALA A 228
THR A 104
 None
None
FAD  A 601 (-3.2A)
None
FAD  A 601 (-4.5A)
 1.31A 4qw1H-5nitA:
undetectable
4qw1N-5nitA:
undetectable		 4qw1H-5nitA:
17.22
4qw1N-5nitA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		3 / 3 GLY A 174
PRO A 175
GLN A 223
 None
 0.58A 4qwpB-5nitA:
undetectable		 4qwpB-5nitA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 11 THR A  33
THR A  34
GLY A  28
ALA A 228
THR A 104
 None
None
FAD  A 601 (-3.2A)
None
FAD  A 601 (-4.5A)
 1.29A 4qwuV-5nitA:
undetectable
4qwub-5nitA:
undetectable		 4qwuV-5nitA:
17.22
4qwub-5nitA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 11 THR A  33
THR A  34
GLY A  28
ALA A 228
THR A 104
 None
None
FAD  A 601 (-3.2A)
None
FAD  A 601 (-4.5A)
 1.29A 4qwuH-5nitA:
undetectable
4qwuN-5nitA:
undetectable		 4qwuH-5nitA:
17.22
4qwuN-5nitA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 11 THR A  33
THR A  34
GLY A  28
ALA A 228
THR A 104
 None
None
FAD  A 601 (-3.2A)
None
FAD  A 601 (-4.5A)
 1.32A 5bxnV-5nitA:
undetectable
5bxnb-5nitA:
undetectable		 5bxnV-5nitA:
17.22
5bxnb-5nitA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 11 THR A  33
THR A  34
GLY A  28
ALA A 228
THR A 104
 None
None
FAD  A 601 (-3.2A)
None
FAD  A 601 (-4.5A)
 1.32A 5bxnH-5nitA:
undetectable
5bxnN-5nitA:
undetectable		 5bxnH-5nitA:
17.22
5bxnN-5nitA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H1E_A_VDXA501_1
(VITAMIN D3 RECEPTOR)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 LEU A 415
ILE A 474
SER A 475
SER A 336
VAL A 425
 None
 1.50A 5h1eA-5nitA:
undetectable		 5h1eA-5nitA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 5 THR A 104
GLU A 231
THR A 170
LEU A 569
 FAD  A 601 (-4.5A)
None
None
None
 1.26A 5hm8D-5nitA:
undetectable		 5hm8D-5nitA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 5 THR A 104
GLU A 231
THR A 170
LEU A 569
 FAD  A 601 (-4.5A)
None
None
None
 1.20A 5hm8G-5nitA:
undetectable		 5hm8G-5nitA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 GLY A 251
VAL A 267
ILE A 297
GLY A  28
GLY A  31
 None
None
None
FAD  A 601 (-3.2A)
None
 0.81A 5koxA-5nitA:
8.3		 5koxA-5nitA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 11 THR A  33
THR A  34
GLY A  28
ALA A 228
THR A 104
 None
None
FAD  A 601 (-3.2A)
None
FAD  A 601 (-4.5A)
 1.31A 5l66V-5nitA:
undetectable
5l66b-5nitA:
undetectable		 5l66V-5nitA:
17.22
5l66b-5nitA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 11 THR A  33
THR A  34
GLY A  28
ALA A 228
THR A 104
 None
None
FAD  A 601 (-3.2A)
None
FAD  A 601 (-4.5A)
 1.31A 5l66H-5nitA:
undetectable
5l66N-5nitA:
undetectable		 5l66H-5nitA:
17.22
5l66N-5nitA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 4 SER A 191
ALA A 188
GLN A 481
THR A 482
 DIO  A 614 (-4.5A)
DIO  A 614 (-3.9A)
None
None
 1.29A 5n0rA-5nitA:
undetectable		 5n0rA-5nitA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 4 SER A 191
ALA A 188
GLN A 481
THR A 482
 DIO  A 614 (-4.5A)
DIO  A 614 (-3.9A)
None
None
 1.27A 5n0sA-5nitA:
undetectable		 5n0sA-5nitA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 4 SER A 191
ALA A 188
GLN A 481
THR A 482
 DIO  A 614 (-4.5A)
DIO  A 614 (-3.9A)
None
None
 1.26A 5n0wA-5nitA:
undetectable		 5n0wA-5nitA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 5 SER A 191
ALA A 188
GLN A 481
THR A 482
 DIO  A 614 (-4.5A)
DIO  A 614 (-3.9A)
None
None
 1.27A 5n0wB-5nitA:
undetectable		 5n0wB-5nitA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 5 SER A 191
ALA A 188
GLN A 481
THR A 482
 DIO  A 614 (-4.5A)
DIO  A 614 (-3.9A)
None
None
 1.27A 5n4iA-5nitA:
undetectable		 5n4iA-5nitA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 TYR A  54
SER A  53
GLY A 101
ALA A 228
GLU A   5
 None
 1.41A 5wbvA-5nitA:
undetectable		 5wbvA-5nitA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		5 / 12 TYR A  54
SER A  53
GLY A 101
ALA A 228
GLU A   5
 None
 1.41A 5wbvB-5nitA:
undetectable		 5wbvB-5nitA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 8 HIS A 210
ASP A 208
ASN A 407
HIS A 115
 None
DIO  A 613 ( 4.5A)
NAG  A 608 (-3.6A)
DIO  A 613 (-3.9A)
 1.04A 5zj8A-5nitA:
undetectable		 5zj8A-5nitA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5nit GLUCOSE OXIDASE
(Aspergillus
niger) 		4 / 6 TYR A 515
ASP A 424
GLN A 464
VAL A 425
 FAD  A 601 (-4.3A)
None
None
None
 1.01A 6djzB-5nitA:
undetectable		 6djzB-5nitA:
17.73