SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nj8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 5nj8 ARYL HYDROCARBON
RECEPTOR
(Homo
sapiens) 		4 / 4 LEU A  72
SER A  75
TYR A  76
LEU A  54
 None
 1.25A 1xz1A-5nj8A:
undetectable		 1xz1A-5nj8A:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 5nj8 ARYL HYDROCARBON
RECEPTOR
(Homo
sapiens) 		4 / 4 LEU A  72
SER A  75
TYR A  76
LEU A  54
 None
 1.27A 1xz3A-5nj8A:
undetectable		 1xz3A-5nj8A:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_B_LNRB200_1
(D7R4 PROTEIN)		 5nj8 ARYL HYDROCARBON
RECEPTOR
ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
(Homo
sapiens) 		5 / 10 GLU B  98
ILE B  97
ARG B 101
HIS B  94
ASP A  65
 None
 1.37A 2qeoB-5nj8B:
undetectable		 2qeoB-5nj8B:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5nj8 ARYL HYDROCARBON
RECEPTOR
(Homo
sapiens) 		5 / 12 VAL A 129
SER A 139
ALA A 269
PHE A 239
LEU A 146
 None
 1.09A 3w67C-5nj8A:
undetectable		 3w67C-5nj8A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5nj8 ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
(Homo
sapiens) 		5 / 12 CYH B 308
VAL B 196
MET B 267
LEU B 221
LEU B 337
 None
 1.32A 4o8fB-5nj8B:
undetectable		 4o8fB-5nj8B:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 5nj8 ARYL HYDROCARBON
RECEPTOR
ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
(Homo
sapiens) 		5 / 11 ARG B 133
LEU B 132
ARG A  49
LEU B 129
LEU A  70
 None
 1.33A 4or0A-5nj8B:
undetectable		 4or0A-5nj8B:
19.14