SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5njo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5njo PUTATIVE CUPIN_2
DOMAIN-CONTAINING
ISOMERASE
(Streptomyces
coeruleorubidus) 		4 / 6 ARG A 112
ASP A  20
ASN A  15
GLU A  45
 None
 1.14A 1rjdA-5njoA:
undetectable		 1rjdA-5njoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5njo PUTATIVE CUPIN_2
DOMAIN-CONTAINING
ISOMERASE
(Streptomyces
coeruleorubidus) 		4 / 6 ARG A 112
ASP A  20
ASN A  15
GLU A  45
 None
 1.09A 1rjdB-5njoA:
undetectable		 1rjdB-5njoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5njo PUTATIVE CUPIN_2
DOMAIN-CONTAINING
ISOMERASE
(Streptomyces
coeruleorubidus) 		4 / 6 ARG A 112
ASP A  20
ASN A  15
GLU A  45
 None
 1.09A 1rjdC-5njoA:
undetectable		 1rjdC-5njoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 5njo PUTATIVE CUPIN_2
DOMAIN-CONTAINING
ISOMERASE
(Streptomyces
coeruleorubidus) 		4 / 6 GLU A 108
TYR A  89
ILE A  87
LEU A  97
 None
 0.99A 1xvaA-5njoA:
undetectable
1xvaB-5njoA:
undetectable		 1xvaA-5njoA:
undetectable
1xvaB-5njoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5njo PUTATIVE CUPIN_2
DOMAIN-CONTAINING
ISOMERASE
(Streptomyces
coeruleorubidus) 		4 / 7 THR A  54
VAL A  96
THR A  98
VAL A  33
 None
 0.35A 3em0B-5njoA:
undetectable		 3em0B-5njoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 5njo PUTATIVE CUPIN_2
DOMAIN-CONTAINING
ISOMERASE
(Streptomyces
coeruleorubidus) 		4 / 6 GLU A 105
PHE A 103
GLU A  12
VAL A  23
 None
 1.22A 5h4dA-5njoA:
undetectable		 5h4dA-5njoA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5njo PUTATIVE CUPIN_2
DOMAIN-CONTAINING
ISOMERASE
(Streptomyces
coeruleorubidus) 		3 / 3 ARG A  86
HIS A  88
ARG A 112
 None
 1.07A 5iaoC-5njoA:
undetectable		 5iaoC-5njoA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5njo PUTATIVE CUPIN_2
DOMAIN-CONTAINING
ISOMERASE
(Streptomyces
coeruleorubidus) 		3 / 3 ARG A  86
HIS A  88
ARG A 112
 None
 1.07A 5iaoF-5njoA:
undetectable		 5iaoF-5njoA:
13.57