SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nkm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 5nkm PROTEIN SMG-8
PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 10 ALA D 185
LEU D 181
ILE E 172
HIS D 352
LEU D 351
 EDO  D 402 (-4.0A)
None
None
None
None
 1.31A 1a52A-5nkmD:
undetectable		 1a52A-5nkmD:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 5nkm PROTEIN SMG-8
PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 10 ALA D 185
LEU D 181
ILE E 172
HIS D 352
LEU D 351
 EDO  D 402 (-4.0A)
None
None
None
None
 1.30A 1a52B-5nkmD:
undetectable		 1a52B-5nkmD:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 5nkm PROTEIN SMG-8
PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 9 ALA D 185
LEU D 181
ILE E 172
HIS D 352
LEU D 351
 EDO  D 402 (-4.0A)
None
None
None
None
 1.25A 1ereA-5nkmD:
undetectable		 1ereA-5nkmD:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 5nkm PROTEIN SMG-8
PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 9 ALA D 185
LEU D 181
ILE E 172
HIS D 352
LEU D 351
 EDO  D 402 (-4.0A)
None
None
None
None
 1.23A 1ereB-5nkmD:
undetectable		 1ereB-5nkmD:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 5nkm PROTEIN SMG-8
PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 9 ALA D 185
LEU D 181
ILE E 172
HIS D 352
LEU D 351
 EDO  D 402 (-4.0A)
None
None
None
None
 1.24A 1ereC-5nkmD:
undetectable		 1ereC-5nkmD:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 5nkm PROTEIN SMG-8
PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 9 ALA D 185
LEU D 181
ILE E 172
HIS D 352
LEU D 351
 EDO  D 402 (-4.0A)
None
None
None
None
 1.23A 1ereD-5nkmD:
undetectable		 1ereD-5nkmD:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 5nkm PROTEIN SMG-8
PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 11 ALA D 185
LEU D 181
ILE E 172
HIS D 352
LEU D 351
 EDO  D 402 (-4.0A)
None
None
None
None
 1.18A 1g50A-5nkmD:
undetectable		 1g50A-5nkmD:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 GLY E  29
ASP E  82
MET E  77
ILE E  28
LEU E 113
 None
 1.13A 1lhuA-5nkmE:
undetectable		 1lhuA-5nkmE:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 5nkm PROTEIN SMG-8
PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 10 ALA D 185
LEU D 181
ILE E 172
HIS D 352
LEU D 351
 EDO  D 402 (-4.0A)
None
None
None
None
 1.30A 1pcgA-5nkmD:
undetectable		 1pcgA-5nkmD:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 5nkm PROTEIN SMG-8
PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 10 ALA D 185
LEU D 181
ILE E 172
HIS D 352
LEU D 351
 EDO  D 402 (-4.0A)
None
None
None
None
 1.22A 1qkuA-5nkmD:
undetectable		 1qkuA-5nkmD:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 5nkm PROTEIN SMG-8
PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 10 ALA D 185
LEU D 181
ILE E 172
HIS D 352
LEU D 351
 EDO  D 402 (-4.0A)
None
None
None
None
 1.23A 1qkuB-5nkmD:
undetectable		 1qkuB-5nkmD:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 5nkm PROTEIN SMG-8
PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 10 ALA D 185
LEU D 181
ILE E 172
HIS D 352
LEU D 351
 EDO  D 402 (-4.0A)
None
None
None
None
 1.23A 1qkuC-5nkmD:
undetectable		 1qkuC-5nkmD:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 5nkm PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 9 ILE D 207
ILE D 206
PHE D 263
VAL D 196
LEU D 259
 None
 1.14A 2m9qA-5nkmD:
undetectable		 2m9qA-5nkmD:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 5nkm PROTEIN SMG-9
(Caenorhabditis
elegans) 		3 / 3 ASP D 325
PHE D 326
LEU D 227
 None
 0.65A 2zi9A-5nkmD:
3.0		 2zi9A-5nkmD:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		4 / 6 ILE E  62
ILE E  22
LEU E 322
MET E 315
 None
 1.12A 3adsA-5nkmE:
undetectable		 3adsA-5nkmE:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 GLY E  64
ASP E   2
ILE E  41
GLY E  38
LEU E  73
 None
 1.05A 3eeyA-5nkmE:
undetectable		 3eeyA-5nkmE:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 GLY E  64
ASP E   2
ILE E  41
GLY E  38
LEU E  73
 None
 1.09A 3eeyC-5nkmE:
undetectable		 3eeyC-5nkmE:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 GLY E  64
ASP E   2
ILE E  41
GLY E  38
LEU E  73
 None
 1.00A 3eeyE-5nkmE:
undetectable		 3eeyE-5nkmE:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 GLY E  64
ASP E   2
ILE E  41
GLY E  38
LEU E  73
 None
 1.02A 3eeyF-5nkmE:
undetectable		 3eeyF-5nkmE:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 GLY E  64
ASP E   2
ILE E  41
GLY E  38
LEU E  73
 None
 1.12A 3eeyH-5nkmE:
undetectable		 3eeyH-5nkmE:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 GLY E  64
ASP E   2
ILE E  41
GLY E  38
LEU E  73
 None
 1.04A 3eeyI-5nkmE:
undetectable		 3eeyI-5nkmE:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 GLY E  64
ASP E   2
ILE E  41
GLY E  38
LEU E  73
 None
 1.03A 3eeyJ-5nkmE:
undetectable		 3eeyJ-5nkmE:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		3 / 3 ASN E 344
HIS E 346
VAL E 399
 None
 0.85A 3elzB-5nkmE:
undetectable		 3elzB-5nkmE:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 5nkm PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 11 LEU D 188
ASP D 208
PHE D 237
ASP D 203
SER D 198
 EDO  D 402 (-3.7A)
None
None
None
None
 1.49A 3ko0O-5nkmD:
undetectable
3ko0P-5nkmD:
undetectable
3ko0Q-5nkmD:
undetectable
3ko0R-5nkmD:
undetectable		 3ko0O-5nkmD:
16.83
3ko0P-5nkmD:
16.83
3ko0Q-5nkmD:
16.83
3ko0R-5nkmD:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 VAL E 183
PRO E 185
GLY E 180
LEU E 318
ILE E 154
 EDO  E 503 ( 3.1A)
None
None
None
None
 0.98A 3ku1H-5nkmE:
undetectable		 3ku1H-5nkmE:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		3 / 3 GLU E  68
PHE E  66
GLN E  71
 None
 0.97A 3r55A-5nkmE:
undetectable		 3r55A-5nkmE:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 LEU E 295
LEU E  45
GLY E  26
LEU E  75
ASP E  70
 None
None
None
None
EDO  E 501 (-4.7A)
 1.28A 3tbgA-5nkmE:
undetectable		 3tbgA-5nkmE:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 LEU E 295
LEU E  45
GLY E  26
LEU E  75
ASP E  70
 None
None
None
None
EDO  E 501 (-4.7A)
 1.28A 3tbgC-5nkmE:
undetectable		 3tbgC-5nkmE:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 LEU E  45
LEU E 295
ILE E  72
ILE E  41
PHE E 294
 None
None
EDO  E 501 ( 4.9A)
None
None
 1.21A 4a79A-5nkmE:
undetectable		 4a79A-5nkmE:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 LEU E  45
LEU E 295
ILE E  72
ILE E  41
PHE E 294
 None
None
EDO  E 501 ( 4.9A)
None
None
 1.21A 4a79B-5nkmE:
undetectable		 4a79B-5nkmE:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 11 LEU E  45
LEU E 295
ILE E  72
ILE E  41
PHE E 294
 None
None
EDO  E 501 ( 4.9A)
None
None
 1.20A 4a7aA-5nkmE:
undetectable		 4a7aA-5nkmE:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 5nkm PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 12 LEU D 282
GLY D  93
ALA D  91
THR D 240
ASP D 150
 None
 0.97A 4dc3A-5nkmD:
3.1		 4dc3A-5nkmD:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		4 / 4 PHE E 191
VAL E 249
ALA E 190
PHE E 294
 None
 1.46A 4f3tA-5nkmE:
undetectable		 4f3tA-5nkmE:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 LEU E 188
LEU E 242
ILE E 132
ILE E 225
LEU E 136
 None
 1.21A 4j26B-5nkmE:
undetectable		 4j26B-5nkmE:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 5nkm PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 11 LEU D 235
LEU D 279
ILE D 207
ILE D  92
PHE D 263
 None
 1.09A 4odrA-5nkmD:
undetectable
4odrB-5nkmD:
undetectable		 4odrA-5nkmD:
13.78
4odrB-5nkmD:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		4 / 8 LEU E 187
ARG E 171
VAL E 183
HIS E 121
 None
EDO  E 503 (-3.2A)
EDO  E 503 ( 3.1A)
None
 1.11A 4qknA-5nkmE:
undetectable		 4qknA-5nkmE:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		4 / 4 PHE E 191
VAL E 249
ALA E 190
PHE E 294
 None
 1.42A 4w5qA-5nkmE:
3.5		 4w5qA-5nkmE:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		4 / 4 PHE E 191
VAL E 249
ALA E 190
PHE E 294
 None
 1.47A 4w5rA-5nkmE:
3.4		 4w5rA-5nkmE:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		4 / 4 PHE E 191
VAL E 249
ALA E 190
PHE E 294
 None
 1.48A 4w5tA-5nkmE:
3.3		 4w5tA-5nkmE:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		4 / 4 PHE E 191
VAL E 249
ALA E 190
PHE E 294
 None
 1.43A 4z4gA-5nkmE:
3.5		 4z4gA-5nkmE:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 5nkm PROTEIN SMG-9
(Caenorhabditis
elegans) 		5 / 9 LEU D 319
LEU D 102
ILE D 312
SER D 104
ALA D 107
 None
 1.10A 4z69A-5nkmD:
undetectable		 4z69A-5nkmD:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		5 / 12 ILE E   3
GLY E  64
GLU E 313
SER E 307
ILE E  22
 None
None
None
EDO  E 505 (-3.0A)
None
 1.40A 5igwA-5nkmE:
undetectable		 5igwA-5nkmE:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5nkm PROTEIN SMG-8
(Caenorhabditis
elegans) 		4 / 4 PHE E 191
VAL E 249
ALA E 190
PHE E 294
 None
 1.42A 5ki6A-5nkmE:
3.2		 5ki6A-5nkmE:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 5nkm PROTEIN SMG-9
(Caenorhabditis
elegans) 		4 / 7 LEU D  79
ALA D  75
ILE D  72
LEU D 339
 None
 0.81A 5te8A-5nkmD:
undetectable		 5te8A-5nkmD:
21.47