SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nks'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		5 / 12 GLY A  21
ALA A  60
ASP A  59
VAL A 445
ILE A 411
 GLY  A  21 ( 0.0A)
ALA  A  60 ( 0.0A)
ASP  A  59 ( 0.6A)
VAL  A 445 ( 0.6A)
ILE  A 411 ( 0.7A)
 1.03A 1hsgB-5nksA:
undetectable		 1hsgB-5nksA:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		5 / 12 GLY A  46
ALA A  33
VAL A  65
ILE A  19
ILE A  24
 GLY  A  46 ( 0.0A)
ALA  A  33 ( 0.0A)
VAL  A  65 ( 0.6A)
ILE  A  19 ( 0.7A)
ILE  A  24 ( 0.7A)
 1.09A 1hsgB-5nksA:
undetectable		 1hsgB-5nksA:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 4 VAL A 328
ALA A 388
LEU A 105
PHE A 392
 VAL  A 328 ( 0.6A)
ALA  A 388 ( 0.0A)
LEU  A 105 ( 0.6A)
PHE  A 392 ( 1.3A)
 1.06A 1q97B-5nksA:
undetectable		 1q97B-5nksA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		6 / 11 GLY A  46
ALA A  33
ASP A  34
VAL A  65
ILE A  19
ILE A  24
 GLY  A  46 ( 0.0A)
ALA  A  33 ( 0.0A)
ASP  A  34 ( 0.6A)
VAL  A  65 ( 0.6A)
ILE  A  19 ( 0.7A)
ILE  A  24 ( 0.7A)
 1.32A 1sdvB-5nksA:
undetectable		 1sdvB-5nksA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 5 LEU A  49
PRO A  52
VAL A  51
ILE A  50
 LEU  A  49 ( 0.6A)
PRO  A  52 ( 1.1A)
VAL  A  51 ( 0.6A)
ILE  A  50 ( 0.6A)
 1.01A 2aoiB-5nksA:
undetectable		 2aoiB-5nksA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		6 / 12 GLY A  46
ALA A  33
ASP A  34
VAL A  65
ILE A  19
ILE A  24
 GLY  A  46 ( 0.0A)
ALA  A  33 ( 0.0A)
ASP  A  34 ( 0.6A)
VAL  A  65 ( 0.6A)
ILE  A  19 ( 0.7A)
ILE  A  24 ( 0.7A)
 1.31A 2avoB-5nksA:
undetectable		 2avoB-5nksA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		5 / 12 GLY A  21
ALA A  60
ASP A  59
VAL A 445
ILE A 411
 GLY  A  21 ( 0.0A)
ALA  A  60 ( 0.0A)
ASP  A  59 ( 0.6A)
VAL  A 445 ( 0.6A)
ILE  A 411 ( 0.7A)
 1.00A 2avsB-5nksA:
undetectable		 2avsB-5nksA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		6 / 12 GLY A  46
ALA A  33
ASP A  34
VAL A  65
ILE A  19
ILE A  24
 GLY  A  46 ( 0.0A)
ALA  A  33 ( 0.0A)
ASP  A  34 ( 0.6A)
VAL  A  65 ( 0.6A)
ILE  A  19 ( 0.7A)
ILE  A  24 ( 0.7A)
 1.31A 2bpxB-5nksA:
undetectable		 2bpxB-5nksA:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 6 PRO A 220
ILE A 217
ASN A 347
LEU A 213
 PRO  A 220 ( 1.1A)
ILE  A 217 ( 0.7A)
ASN  A 347 ( 0.6A)
LEU  A 213 ( 0.5A)
 1.37A 2wekB-5nksA:
undetectable		 2wekB-5nksA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		3 / 3 PRO A 306
GLU A 221
TYR A 290
 PRO  A 306 ( 1.1A)
GLU  A 221 ( 0.6A)
TYR  A 290 ( 1.3A)
 0.79A 2zmbA-5nksA:
undetectable		 2zmbA-5nksA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 4 ILE A 141
GLN A 196
ILE A 187
LEU A 105
 ILE  A 141 ( 0.7A)
GLN  A 196 ( 0.6A)
ILE  A 187 ( 0.6A)
LEU  A 105 ( 0.6A)
 1.25A 3dzyD-5nksA:
undetectable		 3dzyD-5nksA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		5 / 10 ILE A  24
ILE A  45
GLY A 404
TYR A 395
LEU A 409
 ILE  A  24 ( 0.7A)
ILE  A  45 ( 0.7A)
GLY  A 404 ( 0.0A)
TYR  A 395 ( 1.3A)
LEU  A 409 ( 0.5A)
 1.35A 3elzB-5nksA:
undetectable		 3elzB-5nksA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 8 GLY A  99
PHE A 392
PHE A 394
GLY A  68
 GLY  A  99 ( 0.0A)
PHE  A 392 ( 1.3A)
PHE  A 394 ( 1.3A)
GLY  A  68 ( 0.0A)
 0.90A 3ko0O-5nksA:
undetectable
3ko0Q-5nksA:
undetectable		 3ko0O-5nksA:
11.01
3ko0Q-5nksA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 7 GLY A  68
GLY A  99
PHE A 392
PHE A 394
 GLY  A  68 ( 0.0A)
GLY  A  99 ( 0.0A)
PHE  A 392 ( 1.3A)
PHE  A 394 ( 1.3A)
 0.96A 3ko0M-5nksA:
undetectable
3ko0P-5nksA:
undetectable		 3ko0M-5nksA:
11.01
3ko0P-5nksA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		3 / 3 PHE A 167
GLN A 180
PHE A 109
 PHE  A 167 ( 1.3A)
GLN  A 180 ( 0.6A)
PHE  A 109 ( 1.3A)
 0.80A 3rv5A-5nksA:
undetectable		 3rv5A-5nksA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		5 / 12 GLY A 450
ILE A 447
LEU A  41
VAL A  37
ILE A  19
 GLY  A 450 ( 0.0A)
ILE  A 447 ( 0.6A)
LEU  A  41 ( 0.5A)
VAL  A  37 ( 0.6A)
ILE  A  19 ( 0.7A)
 0.88A 4aztA-5nksA:
undetectable		 4aztA-5nksA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		5 / 12 VAL A 437
PHE A 434
GLY A 436
SER A 363
GLU A 367
 VAL  A 437 ( 0.6A)
PHE  A 434 ( 1.3A)
GLY  A 436 ( 0.0A)
SER  A 363 ( 0.0A)
GLU  A 367 ( 0.6A)
 1.36A 4bvaA-5nksA:
1.4		 4bvaA-5nksA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		5 / 12 SER A 385
GLN A 196
THR A 253
ILE A 391
HIS A  73
 SER  A 385 ( 0.0A)
GLN  A 196 ( 0.6A)
THR  A 253 ( 0.8A)
ILE  A 391 ( 0.6A)
HIS  A  73 ( 1.0A)
 1.33A 4c49B-5nksA:
undetectable		 4c49B-5nksA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		3 / 3 HIS A 223
TRP A 295
SER A 304
 HIS  A 223 ( 1.0A)
TRP  A 295 ( 0.5A)
SER  A 304 ( 0.0A)
 1.18A 4lrhD-5nksA:
undetectable		 4lrhD-5nksA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		6 / 12 ASP A  87
GLN A  91
PRO A 463
VAL A 461
ILE A 104
THR A 335
 ASP  A  87 ( 0.5A)
GLN  A  91 ( 0.6A)
PRO  A 463 ( 1.1A)
VAL  A 461 ( 0.6A)
ILE  A 104 ( 0.6A)
THR  A 335 ( 0.8A)
 1.21A 4m2xG-5nksA:
undetectable		 4m2xG-5nksA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		5 / 12 GLY A  46
ALA A  33
VAL A  65
ILE A  19
ILE A  24
 GLY  A  46 ( 0.0A)
ALA  A  33 ( 0.0A)
VAL  A  65 ( 0.6A)
ILE  A  19 ( 0.7A)
ILE  A  24 ( 0.7A)
 1.13A 4njvD-5nksA:
undetectable		 4njvD-5nksA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		5 / 12 GLN A  91
LEU A 427
THR A 335
LEU A  76
GLY A  92
 GLN  A  91 ( 0.6A)
LEU  A 427 ( 0.6A)
THR  A 335 ( 0.8A)
LEU  A  76 ( 0.6A)
GLY  A  92 ( 0.0A)
 1.27A 4o5fA-5nksA:
undetectable
4o5fB-5nksA:
undetectable		 4o5fA-5nksA:
20.29
4o5fB-5nksA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		5 / 12 LEU A  66
GLY A  68
VAL A 445
ILE A  42
VAL A  37
 LEU  A  66 ( 0.6A)
GLY  A  68 ( 0.0A)
VAL  A 445 ( 0.6A)
ILE  A  42 ( 0.6A)
VAL  A  37 ( 0.6A)
 0.97A 4ok1A-5nksA:
undetectable		 4ok1A-5nksA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		3 / 3 GLU A 360
THR A 335
HIS A 333
 GLU  A 360 ( 0.6A)
THR  A 335 ( 0.8A)
HIS  A 333 ( 1.0A)
 0.51A 4q15A-5nksA:
undetectable		 4q15A-5nksA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		3 / 3 GLU A 359
THR A 335
HIS A 333
 GLU  A 359 ( 0.6A)
THR  A 335 ( 0.8A)
HIS  A 333 ( 1.0A)
 0.87A 4q15B-5nksA:
undetectable		 4q15B-5nksA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		3 / 3 GLU A 360
THR A 335
HIS A 333
 GLU  A 360 ( 0.6A)
THR  A 335 ( 0.8A)
HIS  A 333 ( 1.0A)
 0.50A 4q15B-5nksA:
undetectable		 4q15B-5nksA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		5 / 12 GLY A 450
ILE A 447
LEU A  41
VAL A  37
ILE A  19
 GLY  A 450 ( 0.0A)
ILE  A 447 ( 0.6A)
LEU  A  41 ( 0.5A)
VAL  A  37 ( 0.6A)
ILE  A  19 ( 0.7A)
 0.82A 4uw0A-5nksA:
undetectable		 4uw0A-5nksA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		3 / 3 GLU A 360
THR A 335
HIS A 333
 GLU  A 360 ( 0.6A)
THR  A 335 ( 0.8A)
HIS  A 333 ( 1.0A)
 0.52A 4ydqB-5nksA:
undetectable		 4ydqB-5nksA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		5 / 12 GLY A  99
GLY A 100
THR A 101
GLU A 359
ILE A 358
 GLY  A  99 ( 0.0A)
GLY  A 100 ( 0.0A)
THR  A 101 ( 0.8A)
GLU  A 359 ( 0.6A)
ILE  A 358 ( 0.7A)
 1.24A 4zvmA-5nksA:
undetectable
4zvmB-5nksA:
undetectable		 4zvmA-5nksA:
18.43
4zvmB-5nksA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 4 VAL A 139
VAL A 108
TYR A 120
GLN A 122
 VAL  A 139 ( 0.6A)
VAL  A 108 ( 0.5A)
TYR  A 120 ( 1.3A)
GLN  A 122 ( 0.6A)
 1.05A 5qggA-5nksA:
undetectable		 5qggA-5nksA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 4 VAL A 139
VAL A 108
TYR A 120
GLN A 122
 VAL  A 139 ( 0.6A)
VAL  A 108 ( 0.5A)
TYR  A 120 ( 1.3A)
GLN  A 122 ( 0.6A)
 1.04A 5qgoA-5nksA:
undetectable		 5qgoA-5nksA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 4 VAL A 139
VAL A 108
TYR A 120
GLN A 122
 VAL  A 139 ( 0.6A)
VAL  A 108 ( 0.5A)
TYR  A 120 ( 1.3A)
GLN  A 122 ( 0.6A)
 1.05A 5qgpA-5nksA:
undetectable		 5qgpA-5nksA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 4 VAL A 139
VAL A 108
TYR A 120
GLN A 122
 VAL  A 139 ( 0.6A)
VAL  A 108 ( 0.5A)
TYR  A 120 ( 1.3A)
GLN  A 122 ( 0.6A)
 1.06A 5qgqA-5nksA:
undetectable		 5qgqA-5nksA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 4 VAL A 139
VAL A 108
TYR A 120
GLN A 122
 VAL  A 139 ( 0.6A)
VAL  A 108 ( 0.5A)
TYR  A 120 ( 1.3A)
GLN  A 122 ( 0.6A)
 1.08A 5qhbA-5nksA:
undetectable		 5qhbA-5nksA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 6 ASN A  26
PHE A  31
LEU A 409
SER A 405
 ASN  A  26 ( 0.6A)
PHE  A  31 ( 1.3A)
LEU  A 409 ( 0.5A)
SER  A 405 ( 0.0A)
 1.25A 6a7pB-5nksA:
undetectable		 6a7pB-5nksA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5nks DIHYDROPYRIMIDINASE-
RELATED PROTEIN 4
(Homo
sapiens) 		4 / 5 VAL A  70
PHE A 460
MET A 459
GLY A 457
 VAL  A  70 ( 0.6A)
PHE  A 460 ( 1.3A)
MET  A 459 ( 0.0A)
GLY  A 457 ( 0.0A)
 1.40A 6hd4A-5nksA:
undetectable		 6hd4A-5nksA:
10.16