SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nl6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 5nl6 CALPONIN DOMAIN
FAMILY PROTEIN
(Entamoeba
histolytica) 		3 / 3 ASN A 349
ALA A 353
ASN A 277
 None
 0.57A 1n4fA-5nl6A:
undetectable		 1n4fA-5nl6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 5nl6 CALPONIN DOMAIN
FAMILY PROTEIN
(Entamoeba
histolytica) 		4 / 5 ILE A 427
LEU A 424
ASP A 451
ALA A 380
 None
 1.03A 2opxA-5nl6A:
undetectable		 2opxA-5nl6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 5nl6 CALPONIN DOMAIN
FAMILY PROTEIN
(Entamoeba
histolytica) 		3 / 3 ASN A 438
TYR A 285
CYH A 434
 None
None
BME  A 501 (-2.3A)
 1.11A 5lsuB-5nl6A:
undetectable		 5lsuB-5nl6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 5nl6 CALPONIN DOMAIN
FAMILY PROTEIN
(Entamoeba
histolytica) 		4 / 7 ASN A 381
ALA A 382
LYS A 386
GLU A 389
 None
 1.02A 6ci6A-5nl6A:
undetectable		 6ci6A-5nl6A:
17.07