SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nl9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE1_A_CUA502_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5nl9	TRANSCRIPTIONAL REGULATOR (FUR FAMILY) (Leptospira interrogans)	3 / 3	ASP A 103 HIS A 92 HIS A 90	ZN A 201 (-2.6A) ZN A 201 (-3.3A) ZN A 201 (-3.3A)	0.58A	1oe1A-5nl9A: undetectable	1oe1A-5nl9A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OE3_A_CUA502_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5nl9	TRANSCRIPTIONAL REGULATOR (FUR FAMILY) (Leptospira interrogans)	3 / 3	ASP A 103 HIS A 92 HIS A 90	ZN A 201 (-2.6A) ZN A 201 (-3.3A) ZN A 201 (-3.3A)	0.57A	1oe3A-5nl9A: undetectable	1oe3A-5nl9A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JIH_A_097A1001_1 (ADAMTS-1)	5nl9	TRANSCRIPTIONAL REGULATOR (FUR FAMILY) (Leptospira interrogans)	5 / 9	ASP A 95 THR A 138 HIS A 92 HIS A 90 HIS A 36	None None ZN A 201 (-3.3A) ZN A 201 (-3.3A) ZN A 201 (-3.2A)	1.40A	2jihA-5nl9A: undetectable	2jihA-5nl9A: 16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_A_CUA1338_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5nl9	TRANSCRIPTIONAL REGULATOR (FUR FAMILY) (Leptospira interrogans)	3 / 3	ASP A 103 HIS A 92 HIS A 90	ZN A 201 (-2.6A) ZN A 201 (-3.3A) ZN A 201 (-3.3A)	0.61A	2xxgA-5nl9A: undetectable	2xxgA-5nl9A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XXG_C_CUC1339_0 (DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE)	5nl9	TRANSCRIPTIONAL REGULATOR (FUR FAMILY) (Leptospira interrogans)	3 / 3	ASP A 103 HIS A 92 HIS A 90	ZN A 201 (-2.6A) ZN A 201 (-3.3A) ZN A 201 (-3.3A)	0.63A	2xxgC-5nl9A: undetectable	2xxgC-5nl9A: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OE1_A_CUA502_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5nl9","TRANSCRIPTIONAL REGULATOR (FUR FAMILY)","Leptospira interrogans",3,"ASP A 103;HIS A  92;HIS A  90"," ZN A 201 (-2.6A); ZN A 201 (-3.3A); ZN A 201 (-3.3A)","0.58A","1oe1A-5nl9A:undetectable","1oe1A-5nl9A:undetectable"],["1OE3_A_CUA502_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5nl9","TRANSCRIPTIONAL REGULATOR (FUR FAMILY)","Leptospira interrogans",3,"ASP A 103;HIS A  92;HIS A  90"," ZN A 201 (-2.6A); ZN A 201 (-3.3A); ZN A 201 (-3.3A)","0.57A","1oe3A-5nl9A:undetectable","1oe3A-5nl9A:undetectable"],["2JIH_A_097A1001_1","ADAMTS-1","5nl9","TRANSCRIPTIONAL REGULATOR (FUR FAMILY)","Leptospira interrogans",5,"ASP A  95;THR A 138;HIS A  92;HIS A  90;HIS A  36","None;None; ZN A 201 (-3.3A); ZN A 201 (-3.3A); ZN A 201 (-3.2A)","1.40A","2jihA-5nl9A:undetectable","2jihA-5nl9A:16.16"],["2XXG_A_CUA1338_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5nl9","TRANSCRIPTIONAL REGULATOR (FUR FAMILY)","Leptospira interrogans",3,"ASP A 103;HIS A  92;HIS A  90"," ZN A 201 (-2.6A); ZN A 201 (-3.3A); ZN A 201 (-3.3A)","0.61A","2xxgA-5nl9A:undetectable","2xxgA-5nl9A:undetectable"],["2XXG_C_CUC1339_0","DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE","5nl9","TRANSCRIPTIONAL REGULATOR (FUR FAMILY)","Leptospira interrogans",3,"ASP A 103;HIS A  92;HIS A  90"," ZN A 201 (-2.6A); ZN A 201 (-3.3A); ZN A 201 (-3.3A)","0.63A","2xxgC-5nl9A:undetectable","2xxgC-5nl9A:undetectable"]]