SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nlm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		4 / 8 LEU A 294
ARG A 421
GLY A 415
TRP A 389
 None
 0.77A 1fapB-5nlmA:
undetectable		 1fapB-5nlmA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 11 PHE A  72
VAL A 120
LEU A 119
ALA A 118
ALA A 117
 None
 0.99A 1jinA-5nlmA:
undetectable		 1jinA-5nlmA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		4 / 8 VAL A  47
LEU A  27
PRO A  53
SER A  56
 None
None
MG  A1004 (-4.0A)
None
 0.94A 1jtvA-5nlmA:
6.7		 1jtvA-5nlmA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		4 / 7 PHE A 220
ALA A 452
ILE A 248
PRO A 246
 None
 0.89A 1oniA-5nlmA:
undetectable
1oniB-5nlmA:
undetectable		 1oniA-5nlmA:
undetectable
1oniB-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		4 / 6 PHE A 220
ALA A 452
ILE A 248
PRO A 246
 None
 1.16A 1oniH-5nlmA:
undetectable
1oniI-5nlmA:
undetectable		 1oniH-5nlmA:
undetectable
1oniI-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		4 / 7 ILE A 248
PRO A 246
PHE A 220
ALA A 452
 None
 0.89A 1oniG-5nlmA:
undetectable
1oniI-5nlmA:
undetectable		 1oniG-5nlmA:
undetectable
1oniI-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		4 / 7 THR A 376
ASN A 279
LEU A 359
GLN A 355
 None
 1.07A 1qzrA-5nlmA:
undetectable		 1qzrA-5nlmA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		4 / 8 CYH A 371
GLU A 224
THR A 149
SER A 145
 None
None
IOS  A1000 ( 3.7A)
IOS  A1000 ( 3.5A)
 1.13A 2fb2A-5nlmA:
3.1		 2fb2A-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		4 / 4 SER A 475
TRP A 473
ASP A 130
ILE A 129
 None
 1.48A 2oxtD-5nlmA:
undetectable		 2oxtD-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 12 LEU A 359
GLN A 355
VAL A 278
MET A 433
LEU A 276
 None
 1.36A 2q7kA-5nlmA:
undetectable		 2q7kA-5nlmA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		3 / 3 MET A  24
GLU A 378
ASP A 357
 None
 1.06A 3a25A-5nlmA:
4.0		 3a25A-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 9 LEU A 294
ILE A 425
GLY A 422
LEU A 286
SER A 287
 None
 0.93A 3ai9X-5nlmA:
undetectable		 3ai9X-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 9 LEU A 306
ILE A 429
ILE A 425
PHE A 277
VAL A 278
 None
 1.48A 3tmzA-5nlmA:
undetectable		 3tmzA-5nlmA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_B_T3B1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 12 VAL A 384
PHE A 367
GLY A 365
VAL A 275
PHE A 277
 None
None
MG  A1003 (-4.1A)
None
None
 1.14A 4bvaB-5nlmA:
2.8		 4bvaB-5nlmA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 12 VAL A 469
ILE A 228
GLY A 245
ILE A 216
SER A 462
 None
 0.99A 4iv0A-5nlmA:
2.1		 4iv0A-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 12 VAL A 469
ILE A 228
GLY A 245
ILE A 216
SER A 462
 None
 1.04A 4mwzB-5nlmA:
2.3		 4mwzB-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 12 LEU A 306
LEU A 347
GLY A 346
VAL A 309
ILE A 429
 None
 1.40A 4oktA-5nlmA:
undetectable		 4oktA-5nlmA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 12 SER A 108
THR A  44
THR A  70
ALA A  46
ARG A 114
 None
 1.23A 4qvnV-5nlmA:
undetectable
4qvnb-5nlmA:
undetectable		 4qvnV-5nlmA:
14.54
4qvnb-5nlmA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 12 SER A 108
THR A  44
THR A  70
ALA A  46
ARG A 114
 None
 1.22A 4qvnH-5nlmA:
undetectable
4qvnN-5nlmA:
undetectable		 4qvnH-5nlmA:
14.54
4qvnN-5nlmA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 12 SER A 274
GLY A 365
ILE A 425
ALA A 426
GLY A 430
 None
MG  A1003 (-4.1A)
None
None
None
 0.96A 4r29D-5nlmA:
undetectable		 4r29D-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		4 / 8 THR A 146
GLY A 372
ALA A 399
THR A 376
 None
MG  A1002 (-3.5A)
None
None
 0.93A 5eevL-5nlmA:
undetectable
5eevV-5nlmA:
undetectable		 5eevL-5nlmA:
undetectable
5eevV-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		4 / 8 THR A 146
GLY A 372
ALA A 399
THR A 376
 None
MG  A1002 (-3.5A)
None
None
 0.92A 5eewL-5nlmA:
undetectable
5eewV-5nlmA:
undetectable		 5eewL-5nlmA:
undetectable
5eewV-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		4 / 8 THR A 146
GLY A 372
ALA A 399
THR A 376
 None
MG  A1002 (-3.5A)
None
None
 0.93A 5ef3L-5nlmA:
undetectable
5ef3V-5nlmA:
undetectable		 5ef3L-5nlmA:
undetectable
5ef3V-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		3 / 3 GLY A 365
GLY A 366
GLN A 303
 MG  A1003 (-4.1A)
None
None
 0.45A 5imsA-5nlmA:
2.8		 5imsA-5nlmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		4 / 7 PHE A 277
LEU A 306
ALA A 353
GLN A 303
 None
 1.17A 6b89A-5nlmA:
undetectable		 6b89A-5nlmA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 12 GLY A 383
PHE A 142
ILE A 216
LEU A 456
PHE A 220
 None
 0.95A 6e8qA-5nlmA:
undetectable		 6e8qA-5nlmA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 12 SER A 108
THR A  44
THR A  70
ALA A  46
ARG A 114
 None
 1.22A 6hwdV-5nlmA:
undetectable
6hwdb-5nlmA:
undetectable		 6hwdV-5nlmA:
23.53
6hwdb-5nlmA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5nlm INDOXYL
UDP-GLUCOSYLTRANSFER
ASE
(Persicaria
tinctoria) 		5 / 12 SER A 108
THR A  44
THR A  70
ALA A  46
ARG A 114
 None
 1.23A 6hwdH-5nlmA:
undetectable
6hwdN-5nlmA:
undetectable		 6hwdH-5nlmA:
23.53
6hwdN-5nlmA:
18.82