SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nlt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5nlt CVAA9A
(Collariella
virescens) 		4 / 7 GLY A  81
PRO A  82
ILE A 216
GLY A 109
 None
 0.82A 1usqA-5nltA:
undetectable		 1usqA-5nltA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5nlt CVAA9A
(Collariella
virescens) 		4 / 6 GLY A  81
PRO A  82
ILE A 216
GLY A 109
 None
 0.84A 1usqB-5nltA:
undetectable		 1usqB-5nltA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5nlt CVAA9A
(Collariella
virescens) 		4 / 6 GLY A  81
PRO A  82
ILE A 216
GLY A 109
 None
 0.84A 1usqC-5nltA:
undetectable		 1usqC-5nltA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5nlt CVAA9A
(Collariella
virescens) 		4 / 6 GLY A  81
PRO A  82
ILE A 216
GLY A 109
 None
 0.83A 1usqD-5nltA:
undetectable		 1usqD-5nltA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5nlt CVAA9A
(Collariella
virescens) 		4 / 6 GLY A  81
PRO A  82
ILE A 216
GLY A 109
 None
 0.84A 1usqE-5nltA:
undetectable		 1usqE-5nltA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5nlt CVAA9A
(Collariella
virescens) 		4 / 6 GLY A  81
PRO A  82
ILE A 216
GLY A 109
 None
 0.84A 2jklB-5nltA:
undetectable		 2jklB-5nltA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3COT_A_STRA1501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5nlt CVAA9A
(Collariella
virescens) 		4 / 7 TYR A 196
GLU A 147
TYR A 214
TRP A 117
 None
 1.43A 3cotA-5nltA:
undetectable		 3cotA-5nltA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 5nlt CVAA9A
(Collariella
virescens) 		5 / 12 THR A  84
GLY A 218
GLN A 167
VAL A 149
ALA A 150
 None
None
CU  A 301 (-4.4A)
None
None
 1.25A 3t7vA-5nltA:
undetectable		 3t7vA-5nltA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 5nlt CVAA9A
(Collariella
virescens) 		5 / 11 ILE A  87
GLN A 146
LEU A 144
VAL A 175
LEU A 133
 None
 1.10A 4g1bB-5nltA:
undetectable		 4g1bB-5nltA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 5nlt CVAA9A
(Collariella
virescens) 		5 / 9 ILE A  87
GLN A 146
LEU A 144
VAL A 175
LEU A 133
 None
 1.00A 4g1bC-5nltA:
undetectable		 4g1bC-5nltA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 5nlt CVAA9A
(Collariella
virescens) 		4 / 7 GLY A  15
ILE A  22
GLN A 146
TYR A  66
 None
 0.93A 5vlmC-5nltA:
undetectable		 5vlmC-5nltA:
20.15