SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nm7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.78A 1v54A-5nm7G:
undetectable
1v54J-5nm7G:
undetectable		 1v54A-5nm7G:
undetectable
1v54J-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.82A 2dyrA-5nm7G:
undetectable
2dyrJ-5nm7G:
undetectable		 2dyrA-5nm7G:
undetectable
2dyrJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.82A 2dysA-5nm7G:
undetectable
2dysJ-5nm7G:
undetectable		 2dysA-5nm7G:
undetectable
2dysJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.78A 2dysN-5nm7G:
undetectable
2dysW-5nm7G:
undetectable		 2dysN-5nm7G:
undetectable
2dysW-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.79A 2eijA-5nm7G:
undetectable
2eijJ-5nm7G:
undetectable		 2eijA-5nm7G:
undetectable
2eijJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.76A 2eilA-5nm7G:
undetectable
2eilJ-5nm7G:
undetectable		 2eilA-5nm7G:
undetectable
2eilJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.78A 2eimJ-5nm7G:
undetectable		 2eimJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.76A 2eimW-5nm7G:
undetectable		 2eimW-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.74A 2einN-5nm7G:
undetectable
2einW-5nm7G:
undetectable		 2einN-5nm7G:
undetectable
2einW-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.86A 2zxwA-5nm7G:
undetectable
2zxwJ-5nm7G:
undetectable		 2zxwA-5nm7G:
undetectable
2zxwJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.88A 3abmA-5nm7G:
undetectable
3abmJ-5nm7G:
undetectable		 3abmA-5nm7G:
undetectable
3abmJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.88A 3ag1J-5nm7G:
undetectable		 3ag1J-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.99A 3ag1N-5nm7G:
undetectable
3ag1W-5nm7G:
undetectable		 3ag1N-5nm7G:
undetectable
3ag1W-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.80A 3ag2J-5nm7G:
undetectable		 3ag2J-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.85A 3ag4J-5nm7G:
undetectable		 3ag4J-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.82A 3asnA-5nm7G:
undetectable
3asnJ-5nm7G:
undetectable		 3asnA-5nm7G:
undetectable
3asnJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.80A 3asoA-5nm7G:
undetectable
3asoJ-5nm7G:
undetectable		 3asoA-5nm7G:
undetectable
3asoJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		5 / 12 GLY G   8
ILE G  56
GLY G  55
GLN G  46
THR G  61
 None
GLY  G 301 (-4.5A)
None
GLY  G 301 (-4.4A)
GLY  G 301 (-3.7A)
 1.17A 3eeyC-5nm7G:
undetectable		 3eeyC-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3007_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		5 / 9 THR G 176
ALA G 175
LEU G 173
ALA G 164
SER G 165
 None
None
PGE  G 304 (-4.8A)
None
None
 1.23A 3kp6B-5nm7G:
undetectable		 3kp6B-5nm7G:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.79A 3wg7N-5nm7G:
undetectable
3wg7W-5nm7G:
undetectable		 3wg7N-5nm7G:
undetectable
3wg7W-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 SER G 165
GLY G 169
THR G 176
VAL G 196
 None
 1.10A 4eohA-5nm7G:
undetectable		 4eohA-5nm7G:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 7 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.84A 5b1bN-5nm7G:
undetectable
5b1bW-5nm7G:
undetectable		 5b1bN-5nm7G:
undetectable
5b1bW-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 7 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.78A 5b3sN-5nm7G:
undetectable
5b3sW-5nm7G:
undetectable		 5b3sN-5nm7G:
undetectable
5b3sW-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 7 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.78A 5iy5N-5nm7G:
undetectable
5iy5W-5nm7G:
undetectable		 5iy5N-5nm7G:
undetectable
5iy5W-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.79A 5w97J-5nm7G:
undetectable		 5w97J-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.75A 5wauJ-5nm7G:
undetectable		 5wauJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 1.02A 5x19J-5nm7G:
undetectable		 5x19J-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 1.10A 5x1bW-5nm7G:
undetectable		 5x1bW-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 6 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.90A 5x1fA-5nm7G:
undetectable
5x1fJ-5nm7G:
undetectable		 5x1fA-5nm7G:
undetectable
5x1fJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.91A 5x1fW-5nm7G:
undetectable		 5x1fW-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 7 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.96A 5xdqA-5nm7G:
undetectable
5xdqJ-5nm7G:
undetectable		 5xdqA-5nm7G:
undetectable
5xdqJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.91A 5z86J-5nm7G:
undetectable		 5z86J-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 8 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 0.90A 5zcoA-5nm7G:
undetectable
5zcoJ-5nm7G:
undetectable		 5zcoA-5nm7G:
undetectable
5zcoJ-5nm7G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 ALA G 202
TYR G 193
GLN G 210
ILE G 183
 None
 1.38A 6f6sA-5nm7G:
undetectable
6f6sB-5nm7G:
undetectable		 6f6sA-5nm7G:
25.77
6f6sB-5nm7G:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nm7 PEPTIDOGLYCAN-BINDIN
G DOMAIN 1
(Burkholderia) 		4 / 5 TYR G 117
ARG G 119
MET G 122
LEU G 126
 None
 1.07A 6nknJ-5nm7G:
undetectable		 6nknJ-5nm7G:
undetectable