SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nm9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IWK_A_CUA1599_0 (NITROUS OXIDE REDUCTASE)	5nm9	MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG (Trichoplax adhaerens)	3 / 3	CYH A 65 CYH A 109 HIS A 126	ZN A 201 (-2.1A) ZN A 201 (-2.3A) ZN A 201 (-3.2A)	0.76A	2iwkA-5nm9A: undetectable	2iwkA-5nm9A: 15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IWK_B_CUB1599_0 (NITROUS OXIDE REDUCTASE)	5nm9	MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG (Trichoplax adhaerens)	3 / 3	CYH A 65 CYH A 109 HIS A 126	ZN A 201 (-2.1A) ZN A 201 (-2.3A) ZN A 201 (-3.2A)	0.78A	2iwkB-5nm9A: undetectable	2iwkB-5nm9A: 15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_I_ACTI504_0 (RNA POLYMERASE 3D-POL)	5nm9	MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG (Trichoplax adhaerens)	3 / 3	VAL A 78 GLY A 80 LYS A 82	None	0.73A	4k50I-5nm9A: undetectable	4k50I-5nm9A: 15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TVT_A_ASCA305_0 (THAUMATIN-1)	5nm9	MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG (Trichoplax adhaerens)	4 / 5	LYS A 44 GLU A 47 PHE A 111 VAL A 120	None	1.24A	4tvtA-5nm9A: undetectable	4tvtA-5nm9A: 19.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2IWK_A_CUA1599_0","NITROUS OXIDE REDUCTASE","5nm9","MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG","Trichoplax adhaerens",3,"CYH A  65;CYH A 109;HIS A 126"," ZN A 201 (-2.1A); ZN A 201 (-2.3A); ZN A 201 (-3.2A)","0.76A","2iwkA-5nm9A:undetectable","2iwkA-5nm9A:15.18"],["2IWK_B_CUB1599_0","NITROUS OXIDE REDUCTASE","5nm9","MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG","Trichoplax adhaerens",3,"CYH A  65;CYH A 109;HIS A 126"," ZN A 201 (-2.1A); ZN A 201 (-2.3A); ZN A 201 (-3.2A)","0.78A","2iwkB-5nm9A:undetectable","2iwkB-5nm9A:15.18"],["4K50_I_ACTI504_0","RNA POLYMERASE 3D-POL","5nm9","MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG","Trichoplax adhaerens",3,"VAL A  78;GLY A  80;LYS A  82","None","0.73A","4k50I-5nm9A:undetectable","4k50I-5nm9A:15.13"],["4TVT_A_ASCA305_0","THAUMATIN-1","5nm9","MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG","Trichoplax adhaerens",4,"LYS A  44;GLU A  47;PHE A 111;VAL A 120","None","1.24A","4tvtA-5nm9A:undetectable","4tvtA-5nm9A:19.43"]]