SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nmi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5nmi CYTOCHROME B
(Bos
taurus) 		5 / 12 LEU C  41
LEU C 197
GLY C  34
HIS C  97
PHE C  90
 None
MJM  C 503 ( 4.6A)
HEM  C 502 (-3.2A)
HEM  C 502 (-3.1A)
HEM  C 501 (-4.6A)
 1.47A 1d4fC-5nmiC:
undetectable		 1d4fC-5nmiC:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 5nmi CYTOCHROME B
(Bos
taurus) 		6 / 12 ALA C 277
ILE C 280
MET C 124
LEU C 301
LEU C 328
LEU C 332
 None
None
None
HEM  C 502 ( 4.8A)
None
None
 1.21A 1dtlA-5nmiC:
undetectable		 1dtlA-5nmiC:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5nmi CYTOCHROME B
(Bos
taurus) 		5 / 12 LEU C 120
LEU C 121
VAL C  98
HIS C  97
HIS C 196
 HEM  C 502 ( 4.0A)
None
HEM  C 502 (-4.1A)
HEM  C 502 (-3.1A)
HEM  C 502 (-3.1A)
 1.38A 1ie9A-5nmiC:
undetectable		 1ie9A-5nmiC:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 5nmi CYTOCHROME B
(Bos
taurus) 		5 / 10 LEU C  94
ALA C 125
VAL C  98
LEU C 301
PHE C  90
 HEM  C 502 (-4.9A)
None
HEM  C 502 (-4.1A)
HEM  C 502 ( 4.8A)
HEM  C 501 (-4.6A)
 1.32A 1rlbE-5nmiC:
undetectable		 1rlbE-5nmiC:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2001_1
(SERUM ALBUMIN)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		5 / 9 ILE A 312
GLY A 261
LEU A 163
ARG A  92
SER A  45
 None
 1.31A 2bxgB-5nmiA:
0.0		 2bxgB-5nmiA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 GLU D 197
GLU D 195
ALA D 119
ARG C  80
TYR C  81
 None
None
None
HEM  C 501 (-3.7A)
None
 1.45A 2cmlA-5nmiD:
undetectable		 2cmlA-5nmiD:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 GLU D 197
GLU D 195
ALA D 119
ARG C  80
TYR C  81
 None
None
None
HEM  C 501 (-3.7A)
None
 1.45A 2cmlB-5nmiD:
undetectable		 2cmlB-5nmiD:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 GLU D 197
GLU D 195
ALA D 119
ARG C  80
TYR C  81
 None
None
None
HEM  C 501 (-3.7A)
None
 1.48A 2cmlD-5nmiD:
undetectable		 2cmlD-5nmiD:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		4 / 7 PHE C  63
ARG C  80
ALA D 119
TYR C 256
 None
HEM  C 501 (-3.7A)
None
None
 1.24A 2e5dA-5nmiC:
undetectable
2e5dB-5nmiC:
undetectable		 2e5dA-5nmiC:
21.81
2e5dB-5nmiC:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		4 / 7 TYR C 256
PHE C  63
ARG C  80
ALA D 119
 None
None
HEM  C 501 (-3.7A)
None
 1.24A 2e5dA-5nmiC:
undetectable
2e5dB-5nmiC:
undetectable		 2e5dA-5nmiC:
21.81
2e5dB-5nmiC:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 5nmi CYTOCHROME B
(Bos
taurus) 		4 / 5 ILE C 218
PRO C 219
PHE C 220
ILE C  27
 None
None
MJM  C 503 (-4.6A)
MJM  C 503 ( 4.4A)
 0.87A 2hjhA-5nmiC:
undetectable		 2hjhA-5nmiC:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 GLU D 197
GLU D 195
ALA D 119
ARG C  80
TYR C  81
 None
None
None
HEM  C 501 (-3.7A)
None
 1.40A 2htqA-5nmiD:
undetectable		 2htqA-5nmiD:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 5nmi CYTOCHROME B
(Bos
taurus) 		5 / 12 GLY C 351
TYR C 347
PRO C 346
ILE C 280
ALA C 354
 None
 0.97A 2plwA-5nmiC:
undetectable		 2plwA-5nmiC:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 VAL A 375
ASP A 378
GLU A  28
 None
 0.71A 2qeuA-5nmiA:
undetectable		 2qeuA-5nmiA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 VAL A 375
ASP A 378
GLU A  28
 None
 0.67A 2qeuC-5nmiA:
undetectable		 2qeuC-5nmiA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA301_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		4 / 6 ARG D 201
ILE C  78
TRP C  77
HIS D 200
 None
None
None
PEE  D 502 (-3.5A)
 1.14A 3deuA-5nmiD:
undetectable		 3deuA-5nmiD:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		5 / 11 LEU A  23
ALA A 212
LEU A 208
ALA A 198
VAL A  39
 None
 1.25A 3e22B-5nmiA:
undetectable		 3e22B-5nmiA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 GLU D 197
GLU D 195
ALA D 119
ARG C  80
TYR C  81
 None
None
None
HEM  C 501 (-3.7A)
None
 1.45A 3ticA-5nmiD:
undetectable		 3ticA-5nmiD:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 GLU D 197
GLU D 195
ALA D 119
ARG C  80
TYR C  81
 None
None
None
HEM  C 501 (-3.7A)
None
 1.48A 3ticB-5nmiD:
undetectable		 3ticB-5nmiD:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 GLU D 197
GLU D 195
ALA D 119
ARG C  80
TYR C  81
 None
None
None
HEM  C 501 (-3.7A)
None
 1.46A 3ticC-5nmiD:
undetectable		 3ticC-5nmiD:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 VAL A 366
LEU A 392
LEU A   8
ILE A 399
 None
 0.80A 3u5kD-5nmiA:
undetectable		 3u5kD-5nmiA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 GLU D 197
GLU D 195
ALA D 119
ARG C  80
TYR C  81
 None
None
None
HEM  C 501 (-3.7A)
None
 1.43A 4cpzE-5nmiD:
undetectable		 4cpzE-5nmiD:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 5nmi CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 ARG D 144
LEU D 147
GLU D 145
 None
 0.64A 4l3gF-5nmiD:
undetectable		 4l3gF-5nmiD:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 ILE A 134
ASP A 142
GLU A 137
VAL A 167
 None
 1.16A 4nkxC-5nmiA:
undetectable		 4nkxC-5nmiA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 ILE A 134
ASP A 142
GLU A 137
VAL A 167
 None
 1.19A 4nkxD-5nmiA:
undetectable		 4nkxD-5nmiA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B
(Bos
taurus;
Bos
taurus) 		3 / 3 ASN C  16
ASP C  20
ASP A 333
 None
CDL  C 505 (-3.9A)
None
 0.56A 4obwD-5nmiC:
undetectable		 4obwD-5nmiC:
20.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 5nmi CYTOCHROME B
(Bos
taurus) 		6 / 12 PHE C 128
GLY C 142
ILE C 268
TYR C 278
LEU C 281
ILE C 298
 None
 1.24A 4pd4C-5nmiC:
51.6		 4pd4C-5nmiC:
50.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		4 / 6 TYR D 115
ARG D 191
GLU D 197
TYR C  81
 None
 1.31A 4twdF-5nmiD:
undetectable
4twdG-5nmiD:
undetectable		 4twdF-5nmiD:
19.87
4twdG-5nmiD:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 5nmi CYTOCHROME B
(Bos
taurus) 		5 / 11 ALA C  62
VAL C 170
GLY C 130
SER C 139
GLY C 142
 None
None
HEM  C 501 (-3.7A)
None
None
 1.17A 4xp4A-5nmiC:
2.2		 4xp4A-5nmiC:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 SER A  45
GLY A  54
GLU A  60
GLY A  56
GLY A 169
 None
 1.11A 4yvgA-5nmiA:
undetectable		 4yvgA-5nmiA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 5nmi CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 ILE D 164
LEU D 113
ILE D 116
LEU D 169
 None
HEC  D 501 ( 4.9A)
HEC  D 501 (-4.3A)
None
 0.90A 5ieoA-5nmiD:
undetectable		 5ieoA-5nmiD:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus;
Bos
taurus) 		4 / 6 GLY D 155
ASP C 254
ILE D 116
TYR D 126
 None
None
HEC  D 501 (-4.3A)
HEC  D 501 (-4.2A)
 1.09A 5iwuA-5nmiD:
undetectable		 5iwuA-5nmiD:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5nmi CYTOCHROME B
(Bos
taurus) 		4 / 7 HIS C 267
ILE C 268
TYR C 278
ARG C 282
 None
 0.83A 5kkzC-5nmiC:
undetectable
5kkzE-5nmiC:
50.3		 5kkzC-5nmiC:
17.57
5kkzE-5nmiC:
48.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5nmi CYTOCHROME B
(Bos
taurus) 		4 / 7 HIS C 267
ILE C 268
TYR C 278
ARG C 282
 None
 0.82A 5kkzK-5nmiC:
50.3
5kkzQ-5nmiC:
undetectable		 5kkzK-5nmiC:
48.24
5kkzQ-5nmiC:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5nmi CYTOCHROME B
(Bos
taurus) 		4 / 7 HIS C 267
ILE C 268
TYR C 278
ARG C 282
 None
 0.90A 5kkzM-5nmiC:
undetectable
5kkzO-5nmiC:
50.3		 5kkzM-5nmiC:
17.57
5kkzO-5nmiC:
48.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 ILE A 241
LEU A 248
GLY A 426
PHE A 425
 None
 0.97A 5kmdC-5nmiA:
undetectable
5kmdD-5nmiA:
undetectable		 5kmdC-5nmiA:
18.75
5kmdD-5nmiA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 5nmi CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 GLU D 197
GLU D 195
ALA D 119
ARG C  80
TYR C  81
 None
None
None
HEM  C 501 (-3.7A)
None
 1.46A 5l17A-5nmiD:
undetectable		 5l17A-5nmiD:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 HIS A  94
GLU A  93
TRP A 262
 None
 1.01A 5odiD-5nmiA:
undetectable		 5odiD-5nmiA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 HIS A  94
GLU A  93
TRP A 262
 None
 0.90A 5odqD-5nmiA:
undetectable		 5odqD-5nmiA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		3 / 3 HIS A  94
GLU A  93
TRP A 262
 None
 0.98A 5odrD-5nmiA:
undetectable		 5odrD-5nmiA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 SER A  81
VAL A  79
ALA A 101
ALA A  84
GLY A  83
 None
 1.31A 5tzoA-5nmiA:
undetectable		 5tzoA-5nmiA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		5 / 12 SER A  81
VAL A  79
ALA A 101
ALA A  84
GLY A  83
 None
 1.30A 5tzoC-5nmiA:
undetectable		 5tzoC-5nmiA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5nmi CYTOCHROME B
(Bos
taurus) 		4 / 5 TRP C 165
THR C 144
ASN C 148
LEU C 262
 None
 1.46A 5vkqA-5nmiC:
4.1
5vkqB-5nmiC:
4.1		 5vkqA-5nmiC:
11.84
5vkqB-5nmiC:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5nmi CYTOCHROME B
(Bos
taurus) 		4 / 5 TRP C 165
THR C 144
ASN C 148
LEU C 262
 None
 1.47A 5vkqC-5nmiC:
4.1
5vkqD-5nmiC:
4.1		 5vkqC-5nmiC:
11.84
5vkqD-5nmiC:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 ARG A  92
GLU A  48
PRO A 170
ILE A 134
 None
 0.96A 6a4iA-5nmiA:
undetectable		 6a4iA-5nmiA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		5 / 10 VAL A 110
ALA A 109
LEU A 208
LEU A 203
LEU A 197
 None
 0.91A 6f5uA-5nmiA:
undetectable
6f5uB-5nmiA:
undetectable		 6f5uA-5nmiA:
11.76
6f5uB-5nmiA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		5 / 10 VAL A 110
ALA A 109
LEU A 208
LEU A 203
LEU A 197
 None
 0.97A 6f6nA-5nmiA:
undetectable
6f6nB-5nmiA:
undetectable		 6f6nA-5nmiA:
11.76
6f6nB-5nmiA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		4 / 6 VAL A 110
LEU A 197
LEU A  23
LEU A 209
 None
 1.02A 6f6sA-5nmiA:
undetectable
6f6sB-5nmiA:
0.3		 6f6sA-5nmiA:
11.76
6f6sB-5nmiA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
(Bos
taurus) 		4 / 8 THR A 372
VAL A 375
GLU A  28
SER A  27
 None
 1.17A 6fbvC-5nmiA:
undetectable		 6fbvC-5nmiA:
17.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 5nmi CYTOCHROME B
(Bos
taurus) 		5 / 10 TRP C  30
TYR C 103
TYR C 104
PHE C 325
VAL C 329
 PEE  C 504 ( 3.6A)
PEE  C 504 (-3.2A)
PEE  C 504 (-4.4A)
PEE  C 504 (-4.6A)
PEE  C 504 ( 4.1A)
 0.27A 6hu9C-5nmiC:
4.8		 6hu9C-5nmiC:
50.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 5nmi CYTOCHROME B
(Bos
taurus) 		5 / 12 TRP C  30
MET C  96
TYR C 103
TYR C 104
TYR C 358
 PEE  C 504 ( 3.6A)
PEE  C 504 (-4.5A)
PEE  C 504 (-3.2A)
PEE  C 504 (-4.4A)
None
 0.58A 6hu9N-5nmiC:
undetectable		 6hu9N-5nmiC:
50.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HU9_N_PCFN606_0
(CYTOCHROME B)		 5nmi CYTOCHROME B
(Bos
taurus) 		5 / 12 TRP C  30
TYR C 103
TYR C 104
VAL C 329
TYR C 358
 PEE  C 504 ( 3.6A)
PEE  C 504 (-3.2A)
PEE  C 504 (-4.4A)
PEE  C 504 ( 4.1A)
None
 0.31A 6hu9N-5nmiC:
undetectable		 6hu9N-5nmiC:
50.53