SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nmp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 THR A  77
PRO A 255
THR A  75
 None
 0.86A 1dscC-5nmpA:
undetectable		 1dscC-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		4 / 8 THR A 199
ASP A  80
ILE A 197
HIS A  74
 None
MN  A 301 ( 2.4A)
None
MN  A 301 ( 3.2A)
 0.89A 1ei6D-5nmpA:
undetectable		 1ei6D-5nmpA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 THR A  75
THR A  77
PRO A 255
 None
 0.77A 1fjaC-5nmpA:
undetectable		 1fjaC-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 THR A  75
THR A  77
PRO A 255
 None
 0.76A 1fjaD-5nmpA:
undetectable		 1fjaD-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 THR A  75
THR A  77
PRO A 255
 None
 0.84A 1i3wE-5nmpA:
undetectable		 1i3wE-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 ALA A 115
VAL A 117
TRP A 123
 None
 0.95A 1magA-5nmpA:
undetectable		 1magA-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 ALA A 115
VAL A 117
TRP A 123
 None
 0.95A 1magB-5nmpA:
undetectable		 1magB-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 ALA A 115
VAL A 117
TRP A 123
 None
 0.85A 1nrmA-5nmpA:
undetectable		 1nrmA-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 ALA A 115
VAL A 117
TRP A 123
 None
 0.86A 1nrmB-5nmpA:
undetectable		 1nrmB-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 ALA A 115
VAL A 117
TRP A 123
 None
 0.86A 1nt5A-5nmpA:
undetectable		 1nt5A-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 ALA A 115
VAL A 117
TRP A 123
 None
 0.86A 1nt5B-5nmpA:
undetectable		 1nt5B-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 THR A  77
PRO A 255
THR A  75
 None
 0.86A 1unjL-5nmpA:
undetectable		 1unjL-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 THR A  75
THR A  77
PRO A 255
 None
 0.82A 1unjW-5nmpA:
undetectable		 1unjW-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 THR A  77
PRO A 255
THR A  75
 None
 0.81A 1unmE-5nmpA:
undetectable		 1unmE-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 THR A  75
THR A  77
PRO A 255
 None
 0.85A 1unmE-5nmpA:
undetectable		 1unmE-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 THR A  75
THR A  77
PRO A 255
 None
 0.83A 209dC-5nmpA:
undetectable		 209dC-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 THR A  77
PRO A 255
THR A  75
 None
 0.74A 316dC-5nmpA:
undetectable		 316dC-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		5 / 8 HIS A 218
HIS A 214
PHE A 192
ASP A  80
GLY A 224
 None
SIN  A 302 (-4.2A)
None
MN  A 301 ( 2.4A)
None
 1.46A 3c0zB-5nmpA:
undetectable		 3c0zB-5nmpA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		4 / 5 ILE A 197
THR A 150
PHE A 148
PHE A 192
 None
 1.35A 3em0A-5nmpA:
undetectable		 3em0A-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		5 / 12 ILE A 197
THR A 172
VAL A 180
LEU A 216
THR A 215
 None
 1.26A 3em0B-5nmpA:
undetectable		 3em0B-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 HIS A 171
ARG A 166
GLU A 167
 None
 0.88A 3qf1A-5nmpA:
undetectable		 3qf1A-5nmpA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		4 / 7 THR A 199
ASP A  80
HIS A  78
ILE A 197
 None
MN  A 301 ( 2.4A)
MN  A 301 (-3.3A)
None
 0.92A 3t01A-5nmpA:
undetectable		 3t01A-5nmpA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 GLN A 203
HIS A 171
ARG A 166
 None
 0.80A 4qyqA-5nmpA:
undetectable		 4qyqA-5nmpA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		3 / 3 GLN A 203
HIS A 171
ARG A 166
 None
 0.73A 4qyqB-5nmpA:
undetectable		 4qyqB-5nmpA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		5 / 12 HIS A  84
GLN A 226
ILE A 197
GLU A  73
SER A 252
 SIN  A 302 (-3.7A)
MN  A 301 ( 3.0A)
None
None
None
 1.21A 4r88B-5nmpA:
undetectable		 4r88B-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		5 / 12 HIS A  84
GLN A 226
ILE A 197
GLU A  73
SER A 252
 SIN  A 302 (-3.7A)
MN  A 301 ( 3.0A)
None
None
None
 1.20A 4r88C-5nmpA:
undetectable		 4r88C-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		5 / 12 ASP A 200
LEU A 228
GLU A 195
ALA A 179
GLU A 181
 None
 1.24A 4retA-5nmpA:
undetectable		 4retA-5nmpA:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		5 / 12 ASP A 200
LEU A 228
GLU A 195
ALA A 179
GLU A 181
 None
 1.24A 4retC-5nmpA:
undetectable		 4retC-5nmpA:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		4 / 4 GLY A 191
LEU A 130
PHE A 129
ILE A 111
 None
 0.99A 4xv2A-5nmpA:
undetectable		 4xv2A-5nmpA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		4 / 6 ASP A  80
HIS A  84
HIS A 214
HIS A  78
 MN  A 301 ( 2.4A)
SIN  A 302 (-3.7A)
SIN  A 302 (-4.2A)
MN  A 301 (-3.3A)
 0.65A 5ncdA-5nmpA:
undetectable
5ncdD-5nmpA:
undetectable		 5ncdA-5nmpA:
undetectable
5ncdD-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		4 / 6 ASP A  80
HIS A  84
HIS A 214
HIS A  78
 MN  A 301 ( 2.4A)
SIN  A 302 (-3.7A)
SIN  A 302 (-4.2A)
MN  A 301 (-3.3A)
 0.62A 5ncdB-5nmpA:
undetectable
5ncdC-5nmpA:
undetectable		 5ncdB-5nmpA:
undetectable
5ncdC-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		4 / 8 ASP A  80
HIS A  84
HIS A 214
HIS A  78
 MN  A 301 ( 2.4A)
SIN  A 302 (-3.7A)
SIN  A 302 (-4.2A)
MN  A 301 (-3.3A)
 0.76A 5nekB-5nmpA:
undetectable		 5nekB-5nmpA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		4 / 8 ASP A  80
HIS A  84
HIS A 214
HIS A  78
 MN  A 301 ( 2.4A)
SIN  A 302 (-3.7A)
SIN  A 302 (-4.2A)
MN  A 301 (-3.3A)
 0.75A 5nekD-5nmpA:
undetectable		 5nekD-5nmpA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		4 / 6 ASP A  80
HIS A  84
HIS A 214
HIS A  78
 MN  A 301 ( 2.4A)
SIN  A 302 (-3.7A)
SIN  A 302 (-4.2A)
MN  A 301 (-3.3A)
 0.70A 5nelA-5nmpA:
undetectable
5nelD-5nmpA:
undetectable		 5nelA-5nmpA:
undetectable
5nelD-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		7 / 12 LEU A  39
HIS A  84
TRP A  85
ASP A 200
GLY A 202
TYR A 211
HIS A 214
 None
SIN  A 302 (-3.7A)
None
None
None
None
SIN  A 302 (-4.2A)
 0.73A 5nnaA-5nmpA:
38.6		 5nnaA-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		7 / 12 LEU A  39
HIS A  84
TRP A  85
ASP A 200
GLY A 202
TYR A 211
HIS A 214
 None
SIN  A 302 (-3.7A)
None
None
None
None
SIN  A 302 (-4.2A)
 0.86A 5nnaB-5nmpA:
38.4		 5nnaB-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		6 / 12 LEU A  39
HIS A  84
TRP A  85
ASP A 200
GLY A 202
HIS A 214
 None
SIN  A 302 (-3.7A)
None
None
None
SIN  A 302 (-4.2A)
 0.70A 5nnaC-5nmpA:
38.4		 5nnaC-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		6 / 12 LEU A  39
HIS A  84
TRP A  85
ASP A 200
TYR A 211
HIS A 214
 None
SIN  A 302 (-3.7A)
None
None
None
SIN  A 302 (-4.2A)
 0.91A 5nnaC-5nmpA:
38.4		 5nnaC-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		7 / 12 LEU A  39
HIS A  84
TRP A  85
ASP A 200
GLY A 202
TYR A 211
HIS A 214
 None
SIN  A 302 (-3.7A)
None
None
None
None
SIN  A 302 (-4.2A)
 0.69A 5nnaD-5nmpA:
38.3		 5nnaD-5nmpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 5nmp ISATIN HYDROLASE
(Ralstonia
solanacearum) 		4 / 4 PHE A  34
LEU A  39
LEU A 163
VAL A  46
 None
 1.32A 5xxiA-5nmpA:
undetectable		 5xxiA-5nmpA:
10.80