SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nms'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5nms 25.3 KDA HEAT SHOCK
PROTEIN,
CHLOROPLASTIC
25.3 KDA HEAT SHOCK
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		3 / 3 LYS B  83
ASP A 100
ASP B 131
 None
 1.14A 2br4A-5nmsB:
undetectable		 2br4A-5nmsB:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 5nms 25.3 KDA HEAT SHOCK
PROTEIN,
CHLOROPLASTIC
25.3 KDA HEAT SHOCK
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		3 / 3 ARG B  98
ASN B 162
ASP A 108
 None
 0.89A 5gwxA-5nmsB:
undetectable		 5gwxA-5nmsB:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 5nms 25.3 KDA HEAT SHOCK
PROTEIN,
CHLOROPLASTIC
25.3 KDA HEAT SHOCK
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		3 / 3 SER A 132
SER A 134
ALA B 158
 None
 0.70A 6dwnC-5nmsA:
undetectable		 6dwnC-5nmsA:
19.27