SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LWC_A_NVPA999_1 (HIV-1 REVERSE TRANSCRIPTASE)	5nmy	LYSOSTAPHIN (Staphylococcus simulans)	5 / 11	LEU A 361 VAL A 282 TYR A 327 GLY A 281 LEU A 258	None	1.44A	1lwcA-5nmyA: undetectable	1lwcA-5nmyA: 8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VRT_A_NVPA999_1 (HIV-1 REVERSE TRANSCRIPTASE)	5nmy	LYSOSTAPHIN (Staphylococcus simulans)	5 / 9	LEU A 361 VAL A 282 TYR A 327 GLY A 281 LEU A 258	None	1.50A	1vrtA-5nmyA: undetectable	1vrtA-5nmyA: 8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HND_A_NVPA999_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	5nmy	LYSOSTAPHIN (Staphylococcus simulans)	5 / 10	LEU A 361 VAL A 282 TYR A 327 GLY A 281 LEU A 258	None	1.48A	2hndA-5nmyA: undetectable	2hndA-5nmyA: 9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HNY_A_NVPA999_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	5nmy	LYSOSTAPHIN (Staphylococcus simulans)	5 / 10	LEU A 361 VAL A 282 TYR A 327 GLY A 281 LEU A 258	None	1.45A	2hnyA-5nmyA: undetectable	2hnyA-5nmyA: 9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HVT_A_NVPA557_1 (HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66))	5nmy	LYSOSTAPHIN (Staphylococcus simulans)	5 / 9	LEU A 361 VAL A 282 TYR A 327 GLY A 281 LEU A 258	None	1.40A	3hvtA-5nmyA: undetectable	3hvtA-5nmyA: 8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LP0_A_NVPA701_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	5nmy	LYSOSTAPHIN (Staphylococcus simulans)	5 / 9	LEU A 361 VAL A 282 TYR A 327 GLY A 281 LEU A 258	None	1.42A	3lp0A-5nmyA: undetectable	3lp0A-5nmyA: 8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LP1_A_NVPA701_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	5nmy	LYSOSTAPHIN (Staphylococcus simulans)	5 / 10	LEU A 361 VAL A 282 TYR A 327 GLY A 281 LEU A 258	None	1.45A	3lp1A-5nmyA: undetectable	3lp1A-5nmyA: 8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QIP_A_NVPA561_1 (REVERSE HIV-1 REVERSE TRANSCRIPTASE P66)	5nmy	LYSOSTAPHIN (Staphylococcus simulans)	5 / 10	LEU A 361 VAL A 282 TYR A 327 GLY A 281 LEU A 258	None	1.46A	3qipA-5nmyA: undetectable	3qipA-5nmyA: 8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HBM_A_NVPA601_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	5nmy	LYSOSTAPHIN (Staphylococcus simulans)	5 / 11	LEU A 361 VAL A 282 TYR A 327 GLY A 281 LEU A 258	None	1.40A	5hbmA-5nmyA: undetectable	5hbmA-5nmyA: 8.62

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LWC_A_NVPA999_1","HIV-1 REVERSE TRANSCRIPTASE","5nmy","LYSOSTAPHIN","Staphylococcus simulans",5,"LEU A 361;VAL A 282;TYR A 327;GLY A 281;LEU A 258","None","1.44A","1lwcA-5nmyA:undetectable","1lwcA-5nmyA:8.57"],["1VRT_A_NVPA999_1","HIV-1 REVERSE TRANSCRIPTASE","5nmy","LYSOSTAPHIN","Staphylococcus simulans",5,"LEU A 361;VAL A 282;TYR A 327;GLY A 281;LEU A 258","None","1.50A","1vrtA-5nmyA:undetectable","1vrtA-5nmyA:8.57"],["2HND_A_NVPA999_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","5nmy","LYSOSTAPHIN","Staphylococcus simulans",5,"LEU A 361;VAL A 282;TYR A 327;GLY A 281;LEU A 258","None","1.48A","2hndA-5nmyA:undetectable","2hndA-5nmyA:9.18"],["2HNY_A_NVPA999_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","5nmy","LYSOSTAPHIN","Staphylococcus simulans",5,"LEU A 361;VAL A 282;TYR A 327;GLY A 281;LEU A 258","None","1.45A","2hnyA-5nmyA:undetectable","2hnyA-5nmyA:9.18"],["3HVT_A_NVPA557_1","HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66)","5nmy","LYSOSTAPHIN","Staphylococcus simulans",5,"LEU A 361;VAL A 282;TYR A 327;GLY A 281;LEU A 258","None","1.40A","3hvtA-5nmyA:undetectable","3hvtA-5nmyA:8.63"],["3LP0_A_NVPA701_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","5nmy","LYSOSTAPHIN","Staphylococcus simulans",5,"LEU A 361;VAL A 282;TYR A 327;GLY A 281;LEU A 258","None","1.42A","3lp0A-5nmyA:undetectable","3lp0A-5nmyA:8.35"],["3LP1_A_NVPA701_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","5nmy","LYSOSTAPHIN","Staphylococcus simulans",5,"LEU A 361;VAL A 282;TYR A 327;GLY A 281;LEU A 258","None","1.45A","3lp1A-5nmyA:undetectable","3lp1A-5nmyA:8.35"],["3QIP_A_NVPA561_1","REVERSE HIV-1 REVERSE TRANSCRIPTASE P66","5nmy","LYSOSTAPHIN","Staphylococcus simulans",5,"LEU A 361;VAL A 282;TYR A 327;GLY A 281;LEU A 258","None","1.46A","3qipA-5nmyA:undetectable","3qipA-5nmyA:8.57"],["5HBM_A_NVPA601_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","5nmy","LYSOSTAPHIN","Staphylococcus simulans",5,"LEU A 361;VAL A 282;TYR A 327;GLY A 281;LEU A 258","None","1.40A","5hbmA-5nmyA:undetectable","5hbmA-5nmyA:8.62"]]