SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nn7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		5 / 12 ILE A  80
PHE A 184
LEU A  27
LEU A  35
PHE A 170
 None
 1.19A 1dtlA-5nn7A:
undetectable		 1dtlA-5nn7A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 7 GLU A  54
LEU A  55
VAL A  61
LEU A  68
 None
 0.95A 1hk3A-5nn7A:
undetectable		 1hk3A-5nn7A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 7 LEU A  41
ILE A  52
GLN A  65
MET A  69
 None
 0.76A 1kglA-5nn7A:
undetectable		 1kglA-5nn7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		3 / 3 ALA A 121
VAL A 123
TRP A 250
 None
 0.82A 1tkqB-5nn7A:
undetectable		 1tkqB-5nn7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 8 SER A 114
ARG A 117
GLN A 209
PHE A 227
 None
 1.26A 1zzuA-5nn7A:
undetectable		 1zzuA-5nn7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		5 / 12 LEU A 197
ILE A 198
LEU A 145
VAL A  83
LEU A  85
 None
 1.07A 2bxfB-5nn7A:
undetectable		 2bxfB-5nn7A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 7 TYR A  90
VAL A 102
ILE A 115
GLY A 132
 None
 1.02A 3gssA-5nn7A:
undetectable		 3gssA-5nn7A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		5 / 9 ALA A 236
VAL A 142
ILE A 115
LEU A 134
ILE A  84
 None
 1.21A 3jw3B-5nn7A:
undetectable		 3jw3B-5nn7A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 5 LEU A  26
LEU A  68
LEU A  48
SER A  47
 None
 0.86A 3vhuA-5nn7A:
undetectable		 3vhuA-5nn7A:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 8 GLY A 141
VAL A 142
ILE A 175
PHE A  34
 None
 0.95A 4fglD-5nn7A:
undetectable		 4fglD-5nn7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		5 / 8 GLY A  86
TYR A  90
PHE A 100
SER A 111
ASN A 146
 None
 0.64A 4wryA-5nn7A:
30.1		 4wryA-5nn7A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		5 / 8 GLY A  86
TYR A  90
PHE A 100
SER A 111
HIS A 210
 None
 0.81A 4wryA-5nn7A:
30.1		 4wryA-5nn7A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		5 / 8 GLY A  86
TYR A  90
PHE A 100
SER A 111
ASN A 146
 None
 0.70A 4wrzA-5nn7A:
29.4		 4wrzA-5nn7A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 8 TYR A  90
PHE A 100
SER A 111
HIS A 210
 None
 0.57A 4wrzA-5nn7A:
29.4		 4wrzA-5nn7A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 7 GLY A  86
TYR A  90
PHE A 100
ASN A 146
 None
 0.69A 4ws0A-5nn7A:
29.3		 4ws0A-5nn7A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 8 GLY A  86
TYR A  90
PHE A 100
SER A 111
 None
 0.68A 4ws1A-5nn7A:
29.4		 4ws1A-5nn7A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 8 GLY A  86
TYR A  90
SER A 111
ASN A 146
 None
 0.56A 4ws1A-5nn7A:
29.4		 4ws1A-5nn7A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 8 TYR A  90
PHE A 100
SER A 111
HIS A 210
 None
 0.51A 4ws1A-5nn7A:
29.4		 4ws1A-5nn7A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		5 / 12 LEU A 145
ILE A 175
TRP A  31
LEU A  27
LEU A  35
 None
 1.30A 4yvpB-5nn7A:
undetectable		 4yvpB-5nn7A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 8 LEU A  41
ILE A  52
GLN A  65
MET A  69
 None
 0.68A 5ljbA-5nn7A:
undetectable		 5ljbA-5nn7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 8 LEU A 217
LEU A 214
ILE A 115
TRP A 187
 None
 0.92A 5ljbA-5nn7A:
undetectable		 5ljbA-5nn7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 5nn7 URACIL-DNA
GLYCOSYLASE
(Human
gammaherpesvirus
8) 		4 / 5 ILE A 115
SER A 114
ALA A 208
LEU A 185
 None
 0.95A 6dwnA-5nn7A:
undetectable		 6dwnA-5nn7A:
22.47