SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nnn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.17A 1c9sL-5nnnA:
undetectable
1c9sM-5nnnA:
undetectable		 1c9sL-5nnnA:
15.08
1c9sM-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 1c9sM-5nnnA:
undetectable
1c9sN-5nnnA:
undetectable		 1c9sM-5nnnA:
15.08
1c9sN-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 1c9sN-5nnnA:
undetectable
1c9sO-5nnnA:
undetectable		 1c9sN-5nnnA:
15.08
1c9sO-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 1c9sS-5nnnA:
undetectable
1c9sT-5nnnA:
undetectable		 1c9sS-5nnnA:
15.08
1c9sT-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.16A 1c9sL-5nnnA:
undetectable
1c9sV-5nnnA:
undetectable		 1c9sL-5nnnA:
15.08
1c9sV-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 12 LEU A2040
LEU A2043
SER A2047
LEU A1956
HIS A1954
 None
None
None
None
GOL  A2302 (-3.9A)
 1.07A 1db1A-5nnnA:
undetectable		 1db1A-5nnnA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 5nnn CTATC
(Chaetomium
thermophilum) 		3 / 3 GLN A2037
TYR A1999
ARG A2053
 None
 0.82A 1gtbA-5nnnA:
undetectable		 1gtbA-5nnnA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.18A 1gtfA-5nnnA:
undetectable
1gtfB-5nnnA:
undetectable		 1gtfA-5nnnA:
15.08
1gtfB-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 1gtfT-5nnnA:
undetectable
1gtfU-5nnnA:
undetectable		 1gtfT-5nnnA:
15.08
1gtfU-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 11 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.17A 1gtfU-5nnnA:
undetectable
1gtfV-5nnnA:
undetectable		 1gtfU-5nnnA:
15.08
1gtfV-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.19A 1gtnG-5nnnA:
undetectable
1gtnH-5nnnA:
undetectable		 1gtnG-5nnnA:
15.08
1gtnH-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 1gtnL-5nnnA:
undetectable
1gtnM-5nnnA:
undetectable		 1gtnL-5nnnA:
15.08
1gtnM-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 11 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 1gtnM-5nnnA:
undetectable
1gtnN-5nnnA:
undetectable		 1gtnM-5nnnA:
15.08
1gtnN-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 1gtnN-5nnnA:
undetectable
1gtnO-5nnnA:
undetectable		 1gtnN-5nnnA:
15.08
1gtnO-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 1gtnR-5nnnA:
undetectable
1gtnS-5nnnA:
undetectable		 1gtnR-5nnnA:
15.08
1gtnS-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.20A 1gtnS-5nnnA:
undetectable
1gtnT-5nnnA:
undetectable		 1gtnS-5nnnA:
15.08
1gtnT-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.31A 1utdQ-5nnnA:
undetectable
1utdR-5nnnA:
undetectable		 1utdQ-5nnnA:
15.08
1utdR-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 12 LEU A2247
ALA A2049
LEU A1956
THR A2083
PHE A2009
 None
 1.27A 2oaxB-5nnnA:
undetectable		 2oaxB-5nnnA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 12 LEU A2247
ALA A2049
LEU A1956
THR A2083
PHE A2009
 None
 1.21A 2oaxC-5nnnA:
undetectable		 2oaxC-5nnnA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		4 / 7 ILE A2197
ARG A2196
TYR A2233
GLU A2219
 None
 1.13A 2qebA-5nnnA:
undetectable		 2qebA-5nnnA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		4 / 7 ILE A2197
ARG A2196
TYR A2233
GLU A2219
 None
 1.15A 2qebB-5nnnA:
undetectable		 2qebB-5nnnA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 12 PHE A1950
LEU A2247
HIS A2081
ALA A2085
SER A2118
 None
 1.31A 3apvA-5nnnA:
undetectable		 3apvA-5nnnA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 12 PHE A1950
LEU A2247
HIS A2081
ALA A2085
SER A2118
 None
 1.45A 3apvA-5nnnA:
undetectable		 3apvA-5nnnA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		3 / 3 VAL A2130
LYS A2129
HIS A2125
 None
None
GOL  A2301 (-3.7A)
 0.91A 3elzA-5nnnA:
undetectable		 3elzA-5nnnA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 5nnn CTATC
(Chaetomium
thermophilum) 		4 / 5 GLY A2108
ASP A2109
GLN A2084
MET A2237
 None
 1.33A 3qx3A-5nnnA:
undetectable		 3qx3A-5nnnA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 5nnn CTATC
(Chaetomium
thermophilum) 		4 / 5 GLY A2108
ASP A2109
GLN A2084
MET A2237
 None
 1.37A 3qx3B-5nnnA:
undetectable		 3qx3B-5nnnA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 5nnn CTATC
(Chaetomium
thermophilum) 		4 / 6 GLN A1960
PHE A2086
PRO A2082
LEU A2247
 None
 1.11A 3tgvB-5nnnA:
undetectable		 3tgvB-5nnnA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 5nnn CTATC
(Chaetomium
thermophilum) 		4 / 6 GLN A1960
PHE A2086
PRO A2082
LEU A2247
 None
 0.99A 3tgvD-5nnnA:
undetectable		 3tgvD-5nnnA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 12 LEU A2247
ALA A2049
LEU A1956
THR A2083
PHE A2009
 None
 1.31A 3vhuA-5nnnA:
undetectable		 3vhuA-5nnnA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 5nnn CTATC
(Chaetomium
thermophilum) 		3 / 3 THR A2209
PRO A2207
THR A2208
 None
 0.88A 4hivD-5nnnA:
undetectable		 4hivD-5nnnA:
4.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 12 CYH A2243
VAL A1958
LEU A2123
ALA A2246
PHE A1950
 None
 1.35A 4rtbA-5nnnA:
undetectable		 4rtbA-5nnnA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 12 THR A1962
ALA A1964
ASP A1965
LEU A1968
PRO A1947
 GOL  A2301 (-3.4A)
None
None
None
None
 1.20A 4xi3A-5nnnA:
undetectable		 4xi3A-5nnnA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eeuC-5nnnA:
undetectable
5eeuD-5nnnA:
undetectable		 5eeuC-5nnnA:
15.08
5eeuD-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eeuG-5nnnA:
undetectable
5eeuH-5nnnA:
undetectable		 5eeuG-5nnnA:
15.08
5eeuH-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5eeuN-5nnnA:
undetectable
5eeuO-5nnnA:
undetectable		 5eeuN-5nnnA:
15.08
5eeuO-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 5eeuP-5nnnA:
undetectable
5eeuQ-5nnnA:
undetectable		 5eeuP-5nnnA:
15.08
5eeuQ-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5eeuR-5nnnA:
undetectable
5eeuS-5nnnA:
undetectable		 5eeuR-5nnnA:
15.08
5eeuS-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5eeuS-5nnnA:
undetectable
5eeuT-5nnnA:
undetectable		 5eeuS-5nnnA:
15.08
5eeuT-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5eeuU-5nnnA:
undetectable
5eeuV-5nnnA:
undetectable		 5eeuU-5nnnA:
15.08
5eeuV-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eevC-5nnnA:
undetectable
5eevD-5nnnA:
undetectable		 5eevC-5nnnA:
15.08
5eevD-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eevG-5nnnA:
undetectable
5eevH-5nnnA:
undetectable		 5eevG-5nnnA:
15.08
5eevH-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5eevN-5nnnA:
undetectable
5eevO-5nnnA:
undetectable		 5eevN-5nnnA:
15.08
5eevO-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 5eevP-5nnnA:
undetectable
5eevQ-5nnnA:
undetectable		 5eevP-5nnnA:
15.08
5eevQ-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5eevR-5nnnA:
undetectable
5eevS-5nnnA:
undetectable		 5eevR-5nnnA:
15.08
5eevS-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5eevS-5nnnA:
undetectable
5eevT-5nnnA:
undetectable		 5eevS-5nnnA:
15.08
5eevT-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5eevU-5nnnA:
undetectable
5eevV-5nnnA:
undetectable		 5eevU-5nnnA:
15.08
5eevV-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eewC-5nnnA:
undetectable
5eewD-5nnnA:
undetectable		 5eewC-5nnnA:
15.08
5eewD-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eewG-5nnnA:
undetectable
5eewH-5nnnA:
undetectable		 5eewG-5nnnA:
15.08
5eewH-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5eewN-5nnnA:
undetectable
5eewO-5nnnA:
undetectable		 5eewN-5nnnA:
15.08
5eewO-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 5eewP-5nnnA:
undetectable
5eewQ-5nnnA:
undetectable		 5eewP-5nnnA:
15.08
5eewQ-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5eewR-5nnnA:
undetectable
5eewS-5nnnA:
undetectable		 5eewR-5nnnA:
15.08
5eewS-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5eewS-5nnnA:
undetectable
5eewT-5nnnA:
undetectable		 5eewS-5nnnA:
15.08
5eewT-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5eewU-5nnnA:
undetectable
5eewV-5nnnA:
undetectable		 5eewU-5nnnA:
15.08
5eewV-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eexC-5nnnA:
undetectable
5eexD-5nnnA:
undetectable		 5eexC-5nnnA:
15.08
5eexD-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eexG-5nnnA:
undetectable
5eexH-5nnnA:
undetectable		 5eexG-5nnnA:
15.08
5eexH-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 11 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eexI-5nnnA:
undetectable
5eexJ-5nnnA:
undetectable		 5eexI-5nnnA:
15.08
5eexJ-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5eexA-5nnnA:
undetectable
5eexK-5nnnA:
undetectable		 5eexA-5nnnA:
15.08
5eexK-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5eexN-5nnnA:
undetectable
5eexO-5nnnA:
undetectable		 5eexN-5nnnA:
15.08
5eexO-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 5eexP-5nnnA:
undetectable
5eexQ-5nnnA:
undetectable		 5eexP-5nnnA:
15.08
5eexQ-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5eexR-5nnnA:
undetectable
5eexS-5nnnA:
undetectable		 5eexR-5nnnA:
15.08
5eexS-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5eexS-5nnnA:
undetectable
5eexT-5nnnA:
undetectable		 5eexS-5nnnA:
15.08
5eexT-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5eexU-5nnnA:
undetectable
5eexV-5nnnA:
undetectable		 5eexU-5nnnA:
15.08
5eexV-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eeyC-5nnnA:
undetectable
5eeyD-5nnnA:
undetectable		 5eeyC-5nnnA:
15.08
5eeyD-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eeyG-5nnnA:
undetectable
5eeyH-5nnnA:
undetectable		 5eeyG-5nnnA:
15.08
5eeyH-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 11 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eeyI-5nnnA:
undetectable
5eeyJ-5nnnA:
undetectable		 5eeyI-5nnnA:
15.08
5eeyJ-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5eeyN-5nnnA:
undetectable
5eeyO-5nnnA:
undetectable		 5eeyN-5nnnA:
15.08
5eeyO-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 5eeyP-5nnnA:
undetectable
5eeyQ-5nnnA:
undetectable		 5eeyP-5nnnA:
15.08
5eeyQ-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5eeyR-5nnnA:
undetectable
5eeyS-5nnnA:
undetectable		 5eeyR-5nnnA:
15.08
5eeyS-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5eeyS-5nnnA:
undetectable
5eeyT-5nnnA:
undetectable		 5eeyS-5nnnA:
15.08
5eeyT-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5eeyU-5nnnA:
undetectable
5eeyV-5nnnA:
undetectable		 5eeyU-5nnnA:
15.08
5eeyV-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eezC-5nnnA:
undetectable
5eezD-5nnnA:
undetectable		 5eezC-5nnnA:
15.08
5eezD-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eezG-5nnnA:
undetectable
5eezH-5nnnA:
undetectable		 5eezG-5nnnA:
15.08
5eezH-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 11 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5eezI-5nnnA:
undetectable
5eezJ-5nnnA:
undetectable		 5eezI-5nnnA:
15.08
5eezJ-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5eezN-5nnnA:
undetectable
5eezO-5nnnA:
undetectable		 5eezN-5nnnA:
15.08
5eezO-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 5eezP-5nnnA:
undetectable
5eezQ-5nnnA:
undetectable		 5eezP-5nnnA:
15.08
5eezQ-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5eezR-5nnnA:
undetectable
5eezS-5nnnA:
undetectable		 5eezR-5nnnA:
15.08
5eezS-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5eezS-5nnnA:
undetectable
5eezT-5nnnA:
undetectable		 5eezS-5nnnA:
15.08
5eezT-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5eezU-5nnnA:
undetectable
5eezV-5nnnA:
undetectable		 5eezU-5nnnA:
15.08
5eezV-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5ef0C-5nnnA:
undetectable
5ef0D-5nnnA:
undetectable		 5ef0C-5nnnA:
15.08
5ef0D-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5ef0G-5nnnA:
undetectable
5ef0H-5nnnA:
undetectable		 5ef0G-5nnnA:
15.08
5ef0H-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 11 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.18A 5ef0I-5nnnA:
undetectable
5ef0J-5nnnA:
undetectable		 5ef0I-5nnnA:
15.08
5ef0J-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5ef0A-5nnnA:
undetectable
5ef0K-5nnnA:
undetectable		 5ef0A-5nnnA:
15.08
5ef0K-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5ef0N-5nnnA:
undetectable
5ef0O-5nnnA:
undetectable		 5ef0N-5nnnA:
15.08
5ef0O-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 5ef0P-5nnnA:
undetectable
5ef0Q-5nnnA:
undetectable		 5ef0P-5nnnA:
15.08
5ef0Q-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5ef0R-5nnnA:
undetectable
5ef0S-5nnnA:
undetectable		 5ef0R-5nnnA:
15.08
5ef0S-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5ef0S-5nnnA:
undetectable
5ef0T-5nnnA:
undetectable		 5ef0S-5nnnA:
15.08
5ef0T-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5ef0U-5nnnA:
undetectable
5ef0V-5nnnA:
undetectable		 5ef0U-5nnnA:
15.08
5ef0V-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5ef1C-5nnnA:
undetectable
5ef1D-5nnnA:
undetectable		 5ef1C-5nnnA:
15.08
5ef1D-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5ef1G-5nnnA:
undetectable
5ef1H-5nnnA:
undetectable		 5ef1G-5nnnA:
15.08
5ef1H-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 11 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5ef1I-5nnnA:
undetectable
5ef1J-5nnnA:
undetectable		 5ef1I-5nnnA:
15.08
5ef1J-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5ef1N-5nnnA:
undetectable
5ef1O-5nnnA:
undetectable		 5ef1N-5nnnA:
15.08
5ef1O-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 5ef1P-5nnnA:
undetectable
5ef1Q-5nnnA:
undetectable		 5ef1P-5nnnA:
15.08
5ef1Q-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5ef1R-5nnnA:
undetectable
5ef1S-5nnnA:
undetectable		 5ef1R-5nnnA:
15.08
5ef1S-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5ef1S-5nnnA:
undetectable
5ef1T-5nnnA:
undetectable		 5ef1S-5nnnA:
15.08
5ef1T-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5ef1U-5nnnA:
undetectable
5ef1V-5nnnA:
undetectable		 5ef1U-5nnnA:
15.08
5ef1V-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5ef2C-5nnnA:
undetectable
5ef2D-5nnnA:
undetectable		 5ef2C-5nnnA:
15.08
5ef2D-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5ef2G-5nnnA:
undetectable
5ef2H-5nnnA:
undetectable		 5ef2G-5nnnA:
15.08
5ef2H-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 11 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5ef2I-5nnnA:
undetectable
5ef2J-5nnnA:
undetectable		 5ef2I-5nnnA:
15.08
5ef2J-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5ef2N-5nnnA:
undetectable
5ef2O-5nnnA:
undetectable		 5ef2N-5nnnA:
15.08
5ef2O-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 5ef2P-5nnnA:
undetectable
5ef2Q-5nnnA:
undetectable		 5ef2P-5nnnA:
15.08
5ef2Q-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5ef2R-5nnnA:
undetectable
5ef2S-5nnnA:
undetectable		 5ef2R-5nnnA:
15.08
5ef2S-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5ef2S-5nnnA:
undetectable
5ef2T-5nnnA:
undetectable		 5ef2S-5nnnA:
15.08
5ef2T-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5ef2U-5nnnA:
undetectable
5ef2V-5nnnA:
undetectable		 5ef2U-5nnnA:
15.08
5ef2V-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 9 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5ef3C-5nnnA:
undetectable
5ef3D-5nnnA:
undetectable		 5ef3C-5nnnA:
15.08
5ef3D-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.17A 5ef3G-5nnnA:
undetectable
5ef3H-5nnnA:
undetectable		 5ef3G-5nnnA:
15.08
5ef3H-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 11 SER A2008
GLY A2074
HIS A2081
THR A2083
ILE A2072
 None
 1.18A 5ef3I-5nnnA:
undetectable
5ef3J-5nnnA:
undetectable		 5ef3I-5nnnA:
15.08
5ef3J-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5ef3A-5nnnA:
undetectable
5ef3K-5nnnA:
undetectable		 5ef3A-5nnnA:
15.08
5ef3K-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5ef3N-5nnnA:
undetectable
5ef3O-5nnnA:
undetectable		 5ef3N-5nnnA:
15.08
5ef3O-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.19A 5ef3P-5nnnA:
undetectable
5ef3Q-5nnnA:
undetectable		 5ef3P-5nnnA:
15.08
5ef3Q-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.18A 5ef3R-5nnnA:
undetectable
5ef3S-5nnnA:
undetectable		 5ef3R-5nnnA:
15.08
5ef3S-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.15A 5ef3S-5nnnA:
undetectable
5ef3T-5nnnA:
undetectable		 5ef3S-5nnnA:
15.08
5ef3T-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nnn CTATC
(Chaetomium
thermophilum) 		5 / 10 GLY A2074
HIS A2081
THR A2083
ILE A2072
SER A2008
 None
 1.16A 5ef3U-5nnnA:
undetectable
5ef3V-5nnnA:
undetectable		 5ef3U-5nnnA:
15.08
5ef3V-5nnnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5nnn CTATC
(Chaetomium
thermophilum) 		3 / 3 MET A2237
GLN A2236
ARG A2235
 None
 1.04A 5ewzB-5nnnA:
undetectable		 5ewzB-5nnnA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5nnn CTATC
(Chaetomium
thermophilum) 		3 / 3 MET A2237
GLN A2236
ARG A2235
 None
 1.05A 5m35B-5nnnA:
undetectable		 5m35B-5nnnA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5nnn CTATC
(Chaetomium
thermophilum) 		3 / 3 MET A2237
GLN A2236
ARG A2235
 None
 1.08A 5m36A-5nnnA:
undetectable		 5m36A-5nnnA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 5nnn CTATC
(Chaetomium
thermophilum) 		4 / 7 SER A2008
HIS A2081
GLY A2074
LEU A2087
 None
 0.94A 6btxA-5nnnA:
undetectable		 6btxA-5nnnA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5nnn CTATC
(Chaetomium
thermophilum) 		3 / 3 LEU A1968
GLN A1971
LYS A1951
 None
 0.98A 6exiA-5nnnA:
8.9		 6exiA-5nnnA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5nnn CTATC
(Chaetomium
thermophilum) 		3 / 3 MET A2237
GLN A2236
ARG A2235
 None
 1.07A 6fn9A-5nnnA:
undetectable		 6fn9A-5nnnA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5nnn CTATC
(Chaetomium
thermophilum) 		3 / 3 MET A2237
GLN A2236
ARG A2235
 None
 1.06A 6fnaB-5nnnA:
undetectable		 6fnaB-5nnnA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5nnn CTATC
(Chaetomium
thermophilum) 		3 / 3 MET A2237
GLN A2236
ARG A2235
 None
 1.08A 6fnbA-5nnnA:
undetectable		 6fnbA-5nnnA:
21.05