SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nns'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_A_IPHA2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		4 / 5 HIS A  80
PRO A  79
TYR A 167
TYR A  36
 CU  A 303 ( 3.3A)
None
None
None
 1.09A 2ombA-5nnsA:
2.4
2ombB-5nnsA:
4.1		 2ombA-5nnsA:
undetectable
2ombB-5nnsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		4 / 7 TYR A  36
HIS A  80
PRO A  79
TYR A 167
 None
CU  A 303 ( 3.3A)
None
None
 0.89A 2ombC-5nnsA:
4.2
2ombD-5nnsA:
4.3		 2ombC-5nnsA:
undetectable
2ombD-5nnsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		4 / 5 HIS A   1
HIS A  80
GLN A 165
TYR A 167
 CU  A 303 (-3.2A)
CU  A 303 ( 3.3A)
GOL  A 309 (-3.3A)
None
 0.58A 4gboA-5nnsA:
8.1		 4gboA-5nnsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		4 / 5 HIS A   1
HIS A  80
GLN A 165
TYR A 167
 CU  A 303 (-3.2A)
CU  A 303 ( 3.3A)
GOL  A 309 (-3.3A)
None
 0.82A 4gboB-5nnsA:
8.2		 4gboB-5nnsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		4 / 5 HIS A   1
HIS A 159
GLN A 165
TYR A 167
 CU  A 303 (-3.2A)
GOL  A 309 (-4.2A)
GOL  A 309 (-3.3A)
None
 0.95A 4gboB-5nnsA:
8.2		 4gboB-5nnsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		5 / 12 VAL A 175
ALA A  66
PHE A 107
SER A 143
GLY A 178
 None
 1.26A 4mm6A-5nnsA:
undetectable		 4mm6A-5nnsA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		5 / 11 VAL A 175
ALA A  66
SER A 143
SER A 142
GLY A 178
 None
 1.17A 4mmaA-5nnsA:
undetectable		 4mmaA-5nnsA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		5 / 12 VAL A 175
ALA A  66
SER A 143
SER A 142
GLY A 178
 None
 1.12A 4mmdB-5nnsA:
undetectable		 4mmdB-5nnsA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		3 / 3 TYR A 215
GLY A  83
PRO A  84
 NAG  A 301 (-4.9A)
None
None
 0.55A 4qwpA-5nnsA:
undetectable		 4qwpA-5nnsA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		4 / 8 TYR A 167
TRP A  78
THR A  81
LEU A 129
 None
 1.47A 5kxiD-5nnsA:
undetectable
5kxiE-5nnsA:
undetectable		 5kxiD-5nnsA:
9.07
5kxiE-5nnsA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_A_CUA301_0
(AA10A)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		4 / 5 HIS A   1
HIS A  80
GLN A 165
TYR A 167
 CU  A 303 (-3.2A)
CU  A 303 ( 3.3A)
GOL  A 309 (-3.3A)
None
 0.56A 5uizA-5nnsA:
8.1		 5uizA-5nnsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_B_CUB301_0
(AA10A)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		4 / 4 HIS A   1
HIS A  80
GLN A 165
TYR A 167
 CU  A 303 (-3.2A)
CU  A 303 ( 3.3A)
GOL  A 309 (-3.3A)
None
 0.81A 5uizB-5nnsA:
8.1		 5uizB-5nnsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_B_CUB301_0
(AA10A)		 5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN
(Heterobasidion
irregulare) 		4 / 4 HIS A   1
HIS A 159
GLN A 165
TYR A 167
 CU  A 303 (-3.2A)
GOL  A 309 (-4.2A)
GOL  A 309 (-3.3A)
None
 0.96A 5uizB-5nnsA:
8.1		 5uizB-5nnsA:
undetectable