SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5no4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 5no4 30S RIBOSOMAL
PROTEIN S7
(Escherichia
coli) 		4 / 7 ALA G 121
SER G  41
SER G  45
THR G  49
 None
U  A1291 ( 4.6A)
None
None
 1.01A 1dvxA-5no4G:
undetectable		 1dvxA-5no4G:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 5no4 30S RIBOSOMAL
PROTEIN S3
(Escherichia
coli) 		5 / 12 LEU C 111
GLY C 148
ARG C 136
PRO C 109
LYS C 108
 None
 1.24A 1y4lA-5no4C:
undetectable		 1y4lA-5no4C:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 5no4 30S RIBOSOMAL
PROTEIN S3
(Escherichia
coli) 		5 / 12 LEU C 115
ALA C 113
ASP C 112
ALA C  71
ASP C 118
 None
 1.25A 3axtA-5no4C:
undetectable		 3axtA-5no4C:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5no4 30S RIBOSOMAL
PROTEIN S7
(Escherichia
coli) 		5 / 12 ILE G  29
GLU G  58
ALA G 128
ALA G  65
VAL G  69
 None
 1.13A 5igpA-5no4G:
undetectable		 5igpA-5no4G:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 5no4 30S RIBOSOMAL
PROTEIN S7
(Escherichia
coli) 		5 / 12 LEU G  66
VAL G  69
PHE G  26
LEU G  23
ARG G 111
 None
 1.12A 5w7pA-5no4G:
undetectable		 5w7pA-5no4G:
14.69