SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5no7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		3 / 3 GLN A 174
ILE A 175
TYR A 176
 None
 0.60A 1vifA-5no7A:
undetectable		 1vifA-5no7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		3 / 3 GLU A 173
ASP A 238
TYR A 250
 None
NAG  A 320 (-4.0A)
None
 0.74A 2yvlB-5no7A:
undetectable		 2yvlB-5no7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEK_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		5 / 12 GLY A  70
ASN A  68
ASN A  76
ASN A  13
HIS A   6
 None
None
NAG  A 304 (-1.8A)
NAG  A 301 (-1.9A)
None
 1.36A 3mekA-5no7A:
undetectable		 3mekA-5no7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_2
(GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		5 / 9 ALA A  71
GLN A  84
ILE A  83
THR A  62
PHE A 141
 None
SO4  A 328 (-4.9A)
None
None
None
 1.42A 3qelD-5no7A:
undetectable		 3qelD-5no7A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWP_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		5 / 12 GLY A  70
ASN A  68
ASN A  76
ASN A  13
HIS A   6
 None
None
NAG  A 304 (-1.8A)
NAG  A 301 (-1.9A)
None
 1.39A 3qwpA-5no7A:
undetectable		 3qwpA-5no7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		4 / 7 ILE A   2
TYR A 176
PRO A  28
HIS A 166
 None
 1.19A 4g5jA-5no7A:
undetectable		 4g5jA-5no7A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		4 / 5 HIS A   1
HIS A  99
GLN A 174
TYR A 176
 None
 0.74A 4gboA-5no7A:
6.6		 4gboA-5no7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		4 / 5 HIS A   1
HIS A  99
GLN A 174
TYR A 176
 None
 0.69A 4gboB-5no7A:
6.5		 4gboB-5no7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		5 / 12 ALA A 242
ILE A 241
ILE A 165
GLY A 172
GLN A 174
 BMA  A 321 ( 4.4A)
MAN  A 322 (-4.7A)
None
None
None
 0.99A 4r3aB-5no7A:
undetectable		 4r3aB-5no7A:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CCL_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		5 / 12 GLY A  70
ASN A  68
ASN A  76
ASN A  13
HIS A   6
 None
None
NAG  A 304 (-1.8A)
NAG  A 301 (-1.9A)
None
 1.34A 5cclA-5no7A:
undetectable		 5cclA-5no7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CCM_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		5 / 12 GLY A  70
ASN A  68
ASN A  76
ASN A  13
HIS A   6
 None
None
NAG  A 304 (-1.8A)
NAG  A 301 (-1.9A)
None
 1.33A 5ccmA-5no7A:
undetectable		 5ccmA-5no7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_A_CUA301_0
(AA10A)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		4 / 5 HIS A   1
HIS A  99
GLN A 174
TYR A 176
 None
 0.70A 5uizA-5no7A:
6.6		 5uizA-5no7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_B_CUB301_0
(AA10A)		 5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE
(Trametes
cinnabarina) 		4 / 4 HIS A   1
HIS A  99
GLN A 174
TYR A 176
 None
 0.70A 5uizB-5no7A:
6.2		 5uizB-5no7A:
undetectable