SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5noa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 10 LEU A 189
VAL A 232
VAL A 239
TYR A 253
GLY A 235
 None
 1.21A 1fkoA-5noaA:
undetectable		 1fkoA-5noaA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TRP A 274
TYR A 273
LEU A 324
 None
 1.00A 1kxhA-5noaA:
undetectable		 1kxhA-5noaA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 PHE A 307
TRP A 301
GLU A 370
 None
 1.17A 1mogA-5noaA:
undetectable		 1mogA-5noaA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A 103
ASP A 154
ASN A 152
GLU A 142
 None
 1.31A 1rjdA-5noaA:
undetectable		 1rjdA-5noaA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A 103
ASP A 154
ASN A 152
GLU A 142
 None
 1.32A 1rjdB-5noaA:
undetectable		 1rjdB-5noaA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 TYR A 323
GLU A 288
PHE A 359
GLY A 291
 None
 1.11A 2ha4A-5noaA:
undetectable		 2ha4A-5noaA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A 365
ALA A 367
TRP A 321
LEU A 324
 None
 1.22A 2oaxA-5noaA:
undetectable		 2oaxA-5noaA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_2
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 THR A 123
ASN A  88
TRP A  84
TRP A 231
 None
 1.19A 3jzjA-5noaA:
undetectable		 3jzjA-5noaA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASP A 193
LEU A 189
ASP A 229
LEU A 260
 None
 0.83A 3rozA-5noaA:
undetectable		 3rozA-5noaA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 224
TYR A 205
PRO A 213
TYR A 212
 None
 1.29A 4grqA-5noaA:
undetectable
4grqC-5noaA:
undetectable		 4grqA-5noaA:
12.50
4grqC-5noaA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 368
LEU A 324
GLY A 362
ASN A  41
TYR A 163
 None
 1.20A 4pclA-5noaA:
undetectable		 4pclA-5noaA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 HIS A  87
ASN A  88
LYS A  94
ARG A  53
 None
 1.24A 5db5A-5noaA:
undetectable
5db5B-5noaA:
undetectable		 5db5A-5noaA:
23.06
5db5B-5noaA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5noa FAMILY 88 GLYCOSYL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 7 ALA A  68
GLY A  64
GLY A 362
ASN A  73
THR A  72
 None
 1.48A 5ybbB-5noaA:
undetectable		 5ybbB-5noaA:
19.11