SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5np4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5np4 TRANSCOBALAMIN-2
(Homo
sapiens) 		4 / 4 VAL A 314
THR A 315
GLU A 400
GLU A 403
 None
 1.30A 4l78A-5np4A:
undetectable		 4l78A-5np4A:
5.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 5np4 TRANSCOBALAMIN-2
(Homo
sapiens) 		4 / 5 PHE A 376
VAL A 337
PRO A 386
VAL A 407
 CNC  A 502 ( 4.2A)
None
None
None
 1.42A 6ekzA-5np4A:
undetectable		 6ekzA-5np4A:
20.00