SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5npx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 7 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.87A 2v2gA-5npxS:
undetectable
2v2gB-5npxS:
undetectable		 2v2gA-5npxS:
undetectable
2v2gB-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 7 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.85A 2v2gA-5npxS:
undetectable
2v2gB-5npxS:
undetectable		 2v2gA-5npxS:
undetectable
2v2gB-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 7 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.87A 2v2gC-5npxS:
undetectable
2v2gD-5npxS:
undetectable		 2v2gC-5npxS:
undetectable
2v2gD-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 7 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.86A 2v2gC-5npxS:
undetectable
2v2gD-5npxS:
undetectable		 2v2gC-5npxS:
undetectable
2v2gD-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 8 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.86A 2v32A-5npxS:
undetectable
2v32B-5npxS:
undetectable		 2v32A-5npxS:
undetectable
2v32B-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 8 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.85A 2v32A-5npxS:
undetectable
2v32B-5npxS:
undetectable		 2v32A-5npxS:
undetectable
2v32B-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 8 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.86A 2v32C-5npxS:
undetectable
2v32D-5npxS:
undetectable		 2v32C-5npxS:
undetectable
2v32D-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 8 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.87A 2v32C-5npxS:
undetectable
2v32D-5npxS:
undetectable		 2v32C-5npxS:
undetectable
2v32D-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 8 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.81A 2v41C-5npxS:
undetectable
2v41D-5npxS:
undetectable		 2v41C-5npxS:
undetectable
2v41D-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 8 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.90A 2v41C-5npxS:
undetectable
2v41D-5npxS:
undetectable		 2v41C-5npxS:
undetectable
2v41D-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 7 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.89A 2v41E-5npxS:
undetectable
2v41F-5npxS:
undetectable		 2v41E-5npxS:
undetectable
2v41F-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 7 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.87A 2v41E-5npxS:
undetectable
2v41F-5npxS:
undetectable		 2v41E-5npxS:
undetectable
2v41F-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 8 THR S 430
PRO S 431
VAL S 432
SER S 433
 None
 0.84A 2v41G-5npxS:
undetectable
2v41H-5npxS:
undetectable		 2v41G-5npxS:
undetectable
2v41H-5npxS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		5 / 12 LEU L 201
LEU L 216
PHE L 299
VAL L 263
PHE L 266
 None
 1.14A 2ygpA-5npxL:
undetectable		 2ygpA-5npxL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		5 / 10 TYR L  48
PHE L 147
ILE L 149
VAL L  93
PHE L 128
 None
 1.31A 3ay0A-5npxL:
undetectable		 3ay0A-5npxL:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5npx POLYPROTEIN
POLYPROTEIN
(Broad
bean
stain
virus;
Broad
bean
stain
virus) 		5 / 12 THR L 310
PHE L 354
SER L 238
LEU S 435
VAL S 547
 None
 1.41A 3u9fJ-5npxL:
undetectable
3u9fK-5npxL:
undetectable		 3u9fJ-5npxL:
undetectable
3u9fK-5npxL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 5npx POLYPROTEIN
POLYPROTEIN
(Broad
bean
stain
virus;
Broad
bean
stain
virus) 		3 / 3 ILE L 363
ASN S 434
CYH S 391
 None
 0.79A 6bp4A-5npxL:
undetectable		 6bp4A-5npxL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 5npx POLYPROTEIN
(Broad
bean
stain
virus) 		4 / 8 GLY L 219
GLN L 311
THR L 310
TYR L 236
 None
 1.12A 6eqpA-5npxL:
undetectable		 6eqpA-5npxL:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 5npx POLYPROTEIN
POLYPROTEIN
(Broad
bean
stain
virus;
Broad
bean
stain
virus) 		4 / 6 THR L 233
LEU L 237
THR S 438
LEU L 185
 None
 1.22A 6mvxA-5npxL:
undetectable
6mvxB-5npxL:
undetectable
6mvxC-5npxL:
undetectable		 6mvxA-5npxL:
undetectable
6mvxB-5npxL:
undetectable
6mvxC-5npxL:
undetectable