SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nqd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 8 GLY A 688
LYS A 689
THR A 336
GLY A 681
LEU A 433
 None
 1.11A 1aegA-5nqdA:
undetectable		 1aegA-5nqdA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 ILE A 671
PHE A 659
GLN A 660
THR A 569
ASN A 572
 None
 1.16A 1dhfA-5nqdA:
undetectable		 1dhfA-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 PHE A 620
LEU A 163
VAL A 155
VAL A 607
 None
 0.89A 1dz4A-5nqdA:
undetectable		 1dz4A-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 THR A 788
VAL A 764
THR A 773
VAL A 802
 None
 1.11A 1dz9A-5nqdA:
undetectable		 1dz9A-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 10 GLY A  30
THR A 580
THR A  23
SER A 563
ALA A 173
 F3S  A2005 (-4.1A)
None
None
None
MGD  A2001 ( 4.7A)
 1.36A 1gtnO-5nqdA:
undetectable
1gtnP-5nqdA:
undetectable		 1gtnO-5nqdA:
undetectable
1gtnP-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 9 GLY A  30
THR A 580
THR A  23
SER A 563
ALA A 173
 F3S  A2005 (-4.1A)
None
None
None
MGD  A2001 ( 4.7A)
 1.36A 1gtnQ-5nqdA:
undetectable
1gtnR-5nqdA:
undetectable		 1gtnQ-5nqdA:
undetectable
1gtnR-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)		 5nqd ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		4 / 8 LEU B  79
VAL B  90
TYR B 148
GLY B  89
 None
 1.05A 1jlfA-5nqdB:
undetectable
1jlfB-5nqdB:
undetectable		 1jlfA-5nqdB:
11.49
1jlfB-5nqdB:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 SER A 307
THR A 309
ASN A 419
GLU A 809
 MGD  A2002 ( 3.9A)
None
None
None
 1.19A 1mxgA-5nqdA:
undetectable		 1mxgA-5nqdA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 ILE A 232
TRP A 251
PHE A 247
GLU A 227
 None
 1.13A 1nsiA-5nqdA:
undetectable
1nsiB-5nqdA:
undetectable		 1nsiA-5nqdA:
10.00
1nsiB-5nqdA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 TRP A 251
PHE A 247
GLU A 227
ILE A 232
 None
 1.12A 1nsiA-5nqdA:
undetectable
1nsiB-5nqdA:
undetectable		 1nsiA-5nqdA:
10.00
1nsiB-5nqdA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 ILE A 232
TRP A 251
PHE A 247
GLU A 227
 None
 1.15A 1nsiC-5nqdA:
undetectable
1nsiD-5nqdA:
undetectable		 1nsiC-5nqdA:
10.00
1nsiD-5nqdA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 TRP A 251
PHE A 247
GLU A 227
ILE A 232
 None
 1.06A 1nsiC-5nqdA:
undetectable
1nsiD-5nqdA:
undetectable		 1nsiC-5nqdA:
10.00
1nsiD-5nqdA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 GLY A  32
GLY A  30
THR A 656
VAL A  22
ASN A 245
 None
F3S  A2005 (-4.1A)
None
None
F3S  A2005 (-4.0A)
 1.04A 1nv8A-5nqdA:
undetectable		 1nv8A-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 THR A 788
VAL A 764
THR A 773
VAL A 802
 None
 1.10A 1o76B-5nqdA:
undetectable		 1o76B-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 ASP A  80
TYR A 583
MET A 584
ASP A 585
 None
 1.40A 1t03A-5nqdA:
undetectable		 1t03A-5nqdA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 PHE A 620
LEU A 163
VAL A 155
VAL A 607
 None
 0.91A 1t85A-5nqdA:
undetectable		 1t85A-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.93A 1v54A-5nqdA:
undetectable
1v54J-5nqdA:
undetectable		 1v54A-5nqdA:
undetectable
1v54J-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
MET A 604
THR A 603
LEU A 600
 None
 0.95A 1v54A-5nqdA:
undetectable
1v54J-5nqdA:
undetectable		 1v54A-5nqdA:
undetectable
1v54J-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.88A 1v54N-5nqdA:
undetectable
1v54W-5nqdA:
undetectable		 1v54N-5nqdA:
undetectable
1v54W-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 LEU A 303
ILE A 278
PHE A 314
LEU A 317
LEU A 383
 None
 1.13A 1xdkB-5nqdA:
undetectable		 1xdkB-5nqdA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 474
SER A 166
ILE A 550
HIS A 489
 None
 0.97A 1yajF-5nqdA:
undetectable		 1yajF-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVM_A_TMGA501_1
(METHIONINE
AMINOPEPTIDASE)		 5nqd ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		4 / 7 CYH B 103
TYR B 168
CYH B 121
HIS B 124
 FES  B 201 (-2.2A)
None
FES  B 201 (-2.1A)
FES  B 201 (-3.3A)
 1.45A 1yvmA-5nqdB:
undetectable		 1yvmA-5nqdB:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 11 GLY A 308
SER A 307
LEU A 715
ILE A 380
ALA A 312
 MGD  A2002 (-3.5A)
MGD  A2002 ( 3.9A)
None
None
None
 1.43A 2a58A-5nqdA:
2.4
2a58E-5nqdA:
2.4		 2a58A-5nqdA:
18.75
2a58E-5nqdA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 11 ILE A 380
ALA A 312
GLY A 308
SER A 307
LEU A 715
 None
None
MGD  A2002 (-3.5A)
MGD  A2002 ( 3.9A)
None
 1.43A 2a58C-5nqdA:
2.5
2a58D-5nqdA:
undetectable		 2a58C-5nqdA:
18.75
2a58D-5nqdA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 LEU A 431
ASN A 430
LEU A 428
ALA A 427
LEU A 313
 None
 1.30A 2aa6A-5nqdA:
undetectable		 2aa6A-5nqdA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 5 LEU A 303
PHE A 314
VAL A 233
ALA A 391
 None
 1.17A 2cizA-5nqdA:
undetectable		 2cizA-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.97A 2dyrA-5nqdA:
undetectable
2dyrJ-5nqdA:
undetectable		 2dyrA-5nqdA:
undetectable
2dyrJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
MET A 604
THR A 603
LEU A 600
 None
 0.93A 2dyrA-5nqdA:
undetectable
2dyrJ-5nqdA:
undetectable		 2dyrA-5nqdA:
undetectable
2dyrJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.89A 2dyrN-5nqdA:
undetectable
2dyrW-5nqdA:
undetectable		 2dyrN-5nqdA:
undetectable
2dyrW-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.37A 2dysA-5nqdA:
undetectable
2dysC-5nqdA:
undetectable		 2dysA-5nqdA:
undetectable
2dysC-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.99A 2dysA-5nqdA:
undetectable
2dysJ-5nqdA:
undetectable		 2dysA-5nqdA:
undetectable
2dysJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
MET A 604
THR A 603
LEU A 600
 None
 0.94A 2dysA-5nqdA:
undetectable
2dysJ-5nqdA:
undetectable		 2dysA-5nqdA:
undetectable
2dysJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.37A 2dysN-5nqdA:
undetectable
2dysP-5nqdA:
undetectable		 2dysN-5nqdA:
undetectable
2dysP-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 6 LEU A 163
ARG A 149
MET A 604
THR A 603
LEU A 600
 None
 1.00A 2dysN-5nqdA:
undetectable
2dysW-5nqdA:
undetectable		 2dysN-5nqdA:
undetectable
2dysW-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.38A 2eijA-5nqdA:
undetectable
2eijC-5nqdA:
undetectable		 2eijA-5nqdA:
undetectable
2eijC-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.93A 2eijA-5nqdA:
undetectable
2eijJ-5nqdA:
undetectable		 2eijA-5nqdA:
undetectable
2eijJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
MET A 604
THR A 603
LEU A 600
 None
 0.96A 2eijA-5nqdA:
undetectable
2eijJ-5nqdA:
undetectable		 2eijA-5nqdA:
undetectable
2eijJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.93A 2eikA-5nqdA:
0.4
2eikJ-5nqdA:
undetectable		 2eikA-5nqdA:
undetectable
2eikJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.88A 2eikN-5nqdA:
undetectable
2eikW-5nqdA:
undetectable		 2eikN-5nqdA:
undetectable
2eikW-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.36A 2eilA-5nqdA:
undetectable
2eilC-5nqdA:
undetectable		 2eilA-5nqdA:
undetectable
2eilC-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.89A 2eilA-5nqdA:
undetectable
2eilJ-5nqdA:
undetectable		 2eilA-5nqdA:
undetectable
2eilJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
MET A 604
THR A 603
LEU A 600
 None
 0.92A 2eilA-5nqdA:
undetectable
2eilJ-5nqdA:
undetectable		 2eilA-5nqdA:
undetectable
2eilJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.87A 2eilN-5nqdA:
undetectable
2eilW-5nqdA:
undetectable		 2eilN-5nqdA:
undetectable
2eilW-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 5 ARG A 149
MET A 604
THR A 603
LEU A 600
 None
 1.02A 2eimJ-5nqdA:
undetectable		 2eimJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.38A 2eimN-5nqdA:
undetectable
2eimP-5nqdA:
undetectable		 2eimN-5nqdA:
undetectable
2eimP-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 5 ARG A 149
MET A 604
THR A 603
LEU A 600
 None
 1.01A 2eimW-5nqdA:
undetectable		 2eimW-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.36A 2einA-5nqdA:
undetectable
2einC-5nqdA:
undetectable		 2einA-5nqdA:
undetectable
2einC-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 4 LEU A 313
THR A 309
ILE A 279
HIS A 302
 None
 1.31A 2jfaB-5nqdA:
undetectable		 2jfaB-5nqdA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 ILE A 232
TRP A 251
PHE A 247
GLU A 227
 None
 1.10A 2nsiA-5nqdA:
undetectable
2nsiB-5nqdA:
undetectable		 2nsiA-5nqdA:
10.00
2nsiB-5nqdA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 TRP A 251
PHE A 247
GLU A 227
ILE A 232
 None
 1.11A 2nsiA-5nqdA:
undetectable
2nsiB-5nqdA:
undetectable		 2nsiA-5nqdA:
10.00
2nsiB-5nqdA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 ILE A 232
TRP A 251
PHE A 247
GLU A 227
 None
 1.12A 2nsiC-5nqdA:
undetectable
2nsiD-5nqdA:
undetectable		 2nsiC-5nqdA:
10.00
2nsiD-5nqdA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 TRP A 251
PHE A 247
GLU A 227
ILE A 232
 None
 1.11A 2nsiC-5nqdA:
undetectable
2nsiD-5nqdA:
undetectable		 2nsiC-5nqdA:
10.00
2nsiD-5nqdA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26;
Rhizobium
sp.
NT-26) 		4 / 6 VAL B 137
PHE A 837
PRO A 779
THR A 780
 None
 1.33A 2q6oB-5nqdB:
undetectable		 2q6oB-5nqdB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 10 THR A 119
VAL A  77
VAL A  76
ILE A  88
VAL A  87
 None
 1.48A 2qboA-5nqdA:
undetectable		 2qboA-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X08_A_ASCA1253_0
(CYTOCHROME C
PEROXIDASE,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 9 ALA A 467
ILE A 811
PRO A 202
VAL A 470
ASN A 195
 None
 0.99A 2x08A-5nqdA:
undetectable		 2x08A-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5nqd ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		4 / 8 GLN B 143
TYR B 168
SER B 126
CYH B 121
 None
None
FES  B 201 (-3.1A)
FES  B 201 (-2.1A)
 1.22A 2xz5C-5nqdB:
undetectable
2xz5D-5nqdB:
undetectable		 2xz5C-5nqdB:
undetectable
2xz5D-5nqdB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26;
Rhizobium
sp.
NT-26) 		4 / 8 THR B 142
GLN B 140
SER A  70
TYR B 168
 None
 1.26A 2xz5C-5nqdB:
undetectable
2xz5D-5nqdB:
undetectable		 2xz5C-5nqdB:
undetectable
2xz5D-5nqdB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 THR A 548
ILE A 550
GLY A 551
HIS A 482
 MGD  A2001 (-4.5A)
None
None
None
 0.85A 2y7wC-5nqdA:
undetectable		 2y7wC-5nqdA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26;
Rhizobium
sp.
NT-26) 		4 / 5 GLN B 136
ALA B 141
GLN B 143
ARG A   5
 None
 1.48A 2z0aA-5nqdB:
undetectable		 2z0aA-5nqdB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 11 HIS A 489
ILE A 550
HIS A 482
VAL A 481
SER A 166
 None
 1.49A 2zweA-5nqdA:
undetectable
2zweB-5nqdA:
undetectable		 2zweA-5nqdA:
14.18
2zweB-5nqdA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 11 HIS A 489
ILE A 550
HIS A 482
VAL A 481
SER A 166
 None
 1.48A 2zwfA-5nqdA:
undetectable
2zwfB-5nqdA:
undetectable		 2zwfA-5nqdA:
14.18
2zwfB-5nqdA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 11 HIS A 489
ILE A 550
HIS A 482
VAL A 481
SER A 166
 None
 1.45A 2zwgA-5nqdA:
undetectable
2zwgB-5nqdA:
undetectable		 2zwgA-5nqdA:
14.18
2zwgB-5nqdA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.37A 2zxwA-5nqdA:
undetectable
2zxwC-5nqdA:
undetectable		 2zxwA-5nqdA:
undetectable
2zxwC-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.93A 2zxwA-5nqdA:
undetectable
2zxwJ-5nqdA:
undetectable		 2zxwA-5nqdA:
undetectable
2zxwJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
MET A 604
THR A 603
LEU A 600
 None
 0.93A 2zxwA-5nqdA:
undetectable
2zxwJ-5nqdA:
undetectable		 2zxwA-5nqdA:
undetectable
2zxwJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 1.00A 3ablA-5nqdA:
undetectable
3ablJ-5nqdA:
undetectable		 3ablA-5nqdA:
undetectable
3ablJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 1.05A 3abmA-5nqdA:
undetectable
3abmJ-5nqdA:
undetectable		 3abmA-5nqdA:
undetectable
3abmJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
MET A 604
THR A 603
LEU A 600
 None
 0.97A 3abmA-5nqdA:
undetectable
3abmJ-5nqdA:
undetectable		 3abmA-5nqdA:
undetectable
3abmJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.36A 3abmN-5nqdA:
undetectable
3abmP-5nqdA:
undetectable		 3abmN-5nqdA:
undetectable
3abmP-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 LEU A 163
ARG A 149
MET A 604
THR A 603
 None
 0.88A 3ag2N-5nqdA:
undetectable
3ag2W-5nqdA:
undetectable		 3ag2N-5nqdA:
undetectable
3ag2W-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.35A 3ag3N-5nqdA:
undetectable
3ag3P-5nqdA:
undetectable		 3ag3N-5nqdA:
undetectable
3ag3P-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.37A 3ag4A-5nqdA:
undetectable
3ag4C-5nqdA:
undetectable		 3ag4A-5nqdA:
undetectable
3ag4C-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.98A 3asnA-5nqdA:
undetectable
3asnJ-5nqdA:
undetectable		 3asnA-5nqdA:
undetectable
3asnJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
MET A 604
THR A 603
LEU A 600
 None
 0.97A 3asnA-5nqdA:
undetectable
3asnJ-5nqdA:
undetectable		 3asnA-5nqdA:
undetectable
3asnJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.91A 3asnN-5nqdA:
undetectable
3asnW-5nqdA:
undetectable		 3asnN-5nqdA:
undetectable
3asnW-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.97A 3asoA-5nqdA:
undetectable
3asoJ-5nqdA:
undetectable		 3asoA-5nqdA:
undetectable
3asoJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
MET A 604
THR A 603
LEU A 600
 None
 0.95A 3asoA-5nqdA:
undetectable
3asoJ-5nqdA:
undetectable		 3asoA-5nqdA:
undetectable
3asoJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 ALA A 229
GLY A 410
GLY A 444
GLY A 443
ALA A 234
 None
 0.95A 3douA-5nqdA:
3.4		 3douA-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		3 / 3 TYR A 815
ASP A 471
HIS A 199
 MGD  A2001 (-3.4A)
None
MGD  A2001 (-4.5A)
 0.89A 3e23A-5nqdA:
undetectable		 3e23A-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 ILE A 232
TRP A 251
PHE A 247
GLU A 227
 None
 1.10A 3e7gA-5nqdA:
undetectable
3e7gB-5nqdA:
undetectable		 3e7gA-5nqdA:
10.70
3e7gB-5nqdA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 TRP A 251
PHE A 247
GLU A 227
ILE A 232
 None
 1.10A 3e7gA-5nqdA:
undetectable
3e7gB-5nqdA:
undetectable		 3e7gA-5nqdA:
10.70
3e7gB-5nqdA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 ILE A 232
TRP A 251
PHE A 247
GLU A 227
 None
 1.15A 3e7gC-5nqdA:
undetectable
3e7gD-5nqdA:
undetectable		 3e7gC-5nqdA:
10.70
3e7gD-5nqdA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 TRP A 251
PHE A 247
GLU A 227
ILE A 232
 None
 1.14A 3e7gC-5nqdA:
undetectable
3e7gD-5nqdA:
undetectable		 3e7gC-5nqdA:
10.70
3e7gD-5nqdA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 10 VAL A 233
VAL A 235
LEU A 415
GLY A 410
VAL A 445
 None
MGD  A2002 ( 4.8A)
None
None
None
 1.26A 3ls4H-5nqdA:
undetectable		 3ls4H-5nqdA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 THR A 656
ILE A  52
TYR A  36
THR A  23
 None
 1.05A 3q70A-5nqdA:
undetectable		 3q70A-5nqdA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		3 / 3 LEU A 538
MET A 509
ASP A 531
 None
 0.83A 3v5wA-5nqdA:
undetectable		 3v5wA-5nqdA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 4 PRO A  11
LEU A  10
ILE A   7
ARG A   5
 None
 1.35A 3w1wA-5nqdA:
undetectable		 3w1wA-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
ARG A 149
MET A 604
THR A 603
 None
 0.89A 3wg7A-5nqdA:
undetectable
3wg7J-5nqdA:
undetectable		 3wg7A-5nqdA:
undetectable
3wg7J-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_2
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		4 / 5 PHE B 125
PHE A 247
TRP B 138
GLN A 293
 None
 1.39A 4b9zA-5nqdB:
1.8		 4b9zA-5nqdB:
7.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 5nqd ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		4 / 7 ASN B  52
LEU B  54
GLY B 162
TYR B 148
 None
 0.96A 4cp3A-5nqdB:
undetectable
4cp3B-5nqdB:
undetectable		 4cp3A-5nqdB:
17.74
4cp3B-5nqdB:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 ILE A 232
TRP A 251
PHE A 247
GLU A 227
 None
 1.16A 4cx7A-5nqdA:
undetectable
4cx7B-5nqdA:
undetectable		 4cx7A-5nqdA:
10.00
4cx7B-5nqdA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 TRP A 251
PHE A 247
GLU A 227
ILE A 232
 None
 1.08A 4cx7A-5nqdA:
undetectable
4cx7B-5nqdA:
undetectable		 4cx7A-5nqdA:
10.00
4cx7B-5nqdA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 ILE A 232
TRP A 251
PHE A 247
GLU A 227
 None
 1.07A 4cx7C-5nqdA:
undetectable
4cx7D-5nqdA:
undetectable		 4cx7C-5nqdA:
10.00
4cx7D-5nqdA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 TRP A 251
PHE A 247
GLU A 227
ILE A 232
 None
 1.12A 4cx7C-5nqdA:
undetectable
4cx7D-5nqdA:
undetectable		 4cx7C-5nqdA:
10.00
4cx7D-5nqdA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		3 / 3 ARG A 423
TRP A 697
GLY A 699
 None
 0.73A 4e7cA-5nqdA:
undetectable		 4e7cA-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 MET A 633
GLU A 629
GLU A 178
TYR A 177
 None
 1.15A 4mj8A-5nqdA:
undetectable
4mj8C-5nqdA:
undetectable		 4mj8A-5nqdA:
16.35
4mj8C-5nqdA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 ASN A 637
GLU A 629
GLU A 178
TYR A 177
 None
 0.93A 4mj8C-5nqdA:
undetectable		 4mj8C-5nqdA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 MET A 633
GLU A 629
GLU A 178
TYR A 177
 None
 1.22A 4mj8C-5nqdA:
undetectable		 4mj8C-5nqdA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJR_A_0LAA404_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 9 ARG A 506
TYR A 503
GLY A 479
LEU A 163
VAL A 155
 None
 1.47A 4mjrA-5nqdA:
undetectable		 4mjrA-5nqdA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 TRP A 251
PHE A 247
GLU A 227
ILE A 232
 None
 1.19A 4nosA-5nqdA:
undetectable
4nosB-5nqdA:
undetectable		 4nosA-5nqdA:
10.70
4nosB-5nqdA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 ILE A 232
TRP A 251
PHE A 247
GLU A 227
 None
 1.19A 4nosC-5nqdA:
undetectable
4nosD-5nqdA:
undetectable		 4nosC-5nqdA:
10.70
4nosD-5nqdA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 TRP A 251
PHE A 247
GLU A 227
ILE A 232
 None
 1.13A 4nosC-5nqdA:
undetectable
4nosD-5nqdA:
undetectable		 4nosC-5nqdA:
10.70
4nosD-5nqdA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 ASN A 425
GLY A 215
ASP A 213
GLY A 681
ASN A 220
 None
 1.28A 4obwC-5nqdA:
3.5		 4obwC-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		3 / 3 LEU A 568
MET A 577
TYR A  33
 None
 0.90A 4p6xG-5nqdA:
undetectable		 4p6xG-5nqdA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		5 / 10 GLN B 140
CYH A 291
THR A 242
ALA A 239
THR A 237
 None
None
MGD  A2002 (-3.0A)
None
MGD  A2002 (-4.4A)
 1.41A 4qvmH-5nqdB:
0.0
4qvmI-5nqdB:
0.0		 4qvmH-5nqdB:
16.59
4qvmI-5nqdB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		5 / 10 GLN B 140
CYH A 291
THR A 242
ALA A 239
THR A 237
 None
None
MGD  A2002 (-3.0A)
None
MGD  A2002 (-4.4A)
 1.41A 4qvmV-5nqdB:
0.0
4qvmW-5nqdB:
0.0		 4qvmV-5nqdB:
16.59
4qvmW-5nqdB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		5 / 11 GLN B 140
CYH A 291
THR A 242
ALA A 239
THR A 237
 None
None
MGD  A2002 (-3.0A)
None
MGD  A2002 (-4.4A)
 1.43A 4qvnH-5nqdB:
undetectable
4qvnI-5nqdB:
undetectable		 4qvnH-5nqdB:
16.59
4qvnI-5nqdB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		5 / 11 GLN B 140
CYH A 291
THR A 242
ALA A 239
THR A 237
 None
None
MGD  A2002 (-3.0A)
None
MGD  A2002 (-4.4A)
 1.42A 4qvqH-5nqdB:
undetectable
4qvqI-5nqdB:
undetectable		 4qvqH-5nqdB:
16.59
4qvqI-5nqdB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		5 / 11 GLN B 140
CYH A 291
THR A 242
ALA A 239
THR A 237
 None
None
MGD  A2002 (-3.0A)
None
MGD  A2002 (-4.4A)
 1.42A 4qvqV-5nqdB:
undetectable
4qvqW-5nqdB:
undetectable		 4qvqV-5nqdB:
16.59
4qvqW-5nqdB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		5 / 11 GLN B 140
CYH A 291
THR A 242
ALA A 239
THR A 237
 None
None
MGD  A2002 (-3.0A)
None
MGD  A2002 (-4.4A)
 1.41A 4qw3V-5nqdB:
undetectable
4qw3W-5nqdB:
undetectable		 4qw3V-5nqdB:
16.59
4qw3W-5nqdB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		5 / 11 GLN B 140
CYH A 291
THR A 242
ALA A 239
THR A 237
 None
None
MGD  A2002 (-3.0A)
None
MGD  A2002 (-4.4A)
 1.42A 4qwuH-5nqdB:
undetectable
4qwuI-5nqdB:
undetectable		 4qwuH-5nqdB:
16.59
4qwuI-5nqdB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		5 / 11 GLN B 140
CYH A 291
THR A 242
ALA A 239
THR A 237
 None
None
MGD  A2002 (-3.0A)
None
MGD  A2002 (-4.4A)
 1.42A 4qwuV-5nqdB:
undetectable
4qwuW-5nqdB:
undetectable		 4qwuV-5nqdB:
16.59
4qwuW-5nqdB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 ASN A 637
GLU A 629
GLU A 178
TYR A 177
 None
 0.94A 4r87I-5nqdA:
undetectable		 4r87I-5nqdA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 MET A 633
GLU A 629
GLU A 178
TYR A 177
 None
 1.35A 4r87I-5nqdA:
undetectable		 4r87I-5nqdA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 4 ALA A 432
VAL A 446
GLY A 217
THR A 211
 None
 1.15A 4ubeA-5nqdA:
undetectable		 4ubeA-5nqdA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 VAL A 280
VAL A 235
LEU A 428
THR A 424
ALA A 427
 MGD  A2002 (-4.6A)
MGD  A2002 ( 4.8A)
None
None
None
 1.35A 4yhaA-5nqdA:
undetectable		 4yhaA-5nqdA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 TYR A 411
GLY A 410
LEU A 433
PHE A 331
GLY A 681
 None
 1.10A 4ze1A-5nqdA:
undetectable		 4ze1A-5nqdA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		3 / 3 THR A 782
HIS B 124
LEU A 240
 None
FES  B 201 (-3.3A)
None
 0.73A 5axdA-5nqdA:
undetectable		 5axdA-5nqdA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 GLY A 236
ASP A 281
PRO A 282
ARG A 283
LEU A 448
 MGD  A2002 (-3.4A)
MGD  A2002 (-2.9A)
MGD  A2002 (-4.4A)
MGD  A2002 (-3.8A)
None
 1.02A 5bw4A-5nqdA:
undetectable		 5bw4A-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		3 / 3 ASP A 213
GLU A 218
SER A 353
 None
 0.83A 5bw4B-5nqdA:
2.1		 5bw4B-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 9 PHE A 499
TYR A 503
LEU A 538
GLY A 479
VAL A 470
 None
 1.41A 5cp4A-5nqdA:
undetectable		 5cp4A-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		5 / 11 GLN B 140
CYH A 291
THR A 242
ALA A 239
THR A 237
 None
None
MGD  A2002 (-3.0A)
None
MGD  A2002 (-4.4A)
 1.39A 5cz7H-5nqdB:
undetectable
5cz7I-5nqdB:
undetectable		 5cz7H-5nqdB:
16.59
5cz7I-5nqdB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		5 / 12 GLN B 140
CYH A 291
THR A 242
ALA A 239
THR A 237
 None
None
MGD  A2002 (-3.0A)
None
MGD  A2002 (-4.4A)
 1.39A 5d0xH-5nqdB:
undetectable
5d0xI-5nqdB:
undetectable		 5d0xH-5nqdB:
16.59
5d0xI-5nqdB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 5 ASP A 488
HIS A 489
GLY A 551
ALA A 553
 None
 1.00A 5hwaA-5nqdA:
undetectable		 5hwaA-5nqdA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		3 / 3 ALA A 427
ASN A 430
LEU A 431
 None
 0.35A 5i1nB-5nqdA:
undetectable		 5i1nB-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 GLU A 178
ALA A 597
ALA A 598
LEU A 186
GLY A 184
 None
 1.02A 5igpA-5nqdA:
undetectable		 5igpA-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.92A 5iy5A-5nqdA:
undetectable
5iy5J-5nqdA:
undetectable		 5iy5A-5nqdA:
undetectable
5iy5J-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 VAL A 286
GLN A 726
ARG A 283
GLY A 719
LEU A 791
 None
MGD  A2002 ( 3.3A)
MGD  A2002 (-3.8A)
MGD  A2002 (-3.3A)
None
 1.22A 5m54E-5nqdA:
undetectable		 5m54E-5nqdA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 5nqd ARSENITE OXIDASE
SMALL SUBUNIT AIOB
RIESKE [2FE-2S]
CLUSTER
(Rhizobium
sp.
NT-26) 		5 / 12 ILE B 158
LEU B  79
GLY B  91
ASP B  95
GLY B  89
 None
 1.17A 5nnaD-5nqdB:
undetectable		 5nnaD-5nqdB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 VAL A 280
LEU A 428
THR A 424
ALA A 427
 MGD  A2002 (-4.6A)
None
None
None
 0.87A 5tt3H-5nqdA:
undetectable		 5tt3H-5nqdA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V37_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 GLY A 426
ASN A 425
ASN A 315
HIS A 359
TYR A 347
 None
 1.44A 5v37A-5nqdA:
undetectable		 5v37A-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 5 ARG A 149
MET A 604
THR A 603
LEU A 600
 None
 0.93A 5w97J-5nqdA:
undetectable		 5w97J-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 5 ARG A 149
MET A 604
THR A 603
LEU A 600
 None
 1.05A 5wauJ-5nqdA:
undetectable		 5wauJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 1.01A 5x1fA-5nqdA:
undetectable
5x1fJ-5nqdA:
undetectable		 5x1fA-5nqdA:
undetectable
5x1fJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 8 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.88A 5xdxN-5nqdA:
undetectable
5xdxW-5nqdA:
undetectable		 5xdxN-5nqdA:
undetectable
5xdxW-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 11 HIS A 489
ILE A 550
HIS A 482
VAL A 481
SER A 166
 None
 1.47A 5z0fA-5nqdA:
undetectable
5z0fB-5nqdA:
undetectable		 5z0fA-5nqdA:
13.58
5z0fB-5nqdA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 11 HIS A 489
ILE A 550
HIS A 482
VAL A 481
SER A 166
 None
 1.45A 5z0hA-5nqdA:
undetectable
5z0hB-5nqdA:
undetectable		 5z0hA-5nqdA:
13.58
5z0hB-5nqdA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 11 HIS A 489
ILE A 550
HIS A 482
VAL A 481
SER A 166
 None
 1.49A 5z0iA-5nqdA:
undetectable
5z0iB-5nqdA:
undetectable		 5z0iA-5nqdA:
13.58
5z0iB-5nqdA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 11 HIS A 489
ILE A 550
HIS A 482
VAL A 481
SER A 166
 None
 1.46A 5z0jA-5nqdA:
undetectable
5z0jB-5nqdA:
undetectable		 5z0jA-5nqdA:
13.58
5z0jB-5nqdA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 11 HIS A 489
ILE A 550
HIS A 482
VAL A 481
SER A 166
 None
 1.45A 5z0kA-5nqdA:
undetectable
5z0kB-5nqdA:
undetectable		 5z0kA-5nqdA:
13.58
5z0kB-5nqdA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 11 HIS A 489
ILE A 550
HIS A 482
VAL A 481
SER A 166
 None
 1.46A 5z0lA-5nqdA:
undetectable
5z0lB-5nqdA:
undetectable		 5z0lA-5nqdA:
13.58
5z0lB-5nqdA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 5 ARG A 149
MET A 604
THR A 603
LEU A 600
 None
 1.16A 5z86J-5nqdA:
undetectable		 5z86J-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 ARG A 149
MET A 604
THR A 603
LEU A 600
 None
 0.98A 5z86N-5nqdA:
undetectable
5z86W-5nqdA:
undetectable		 5z86N-5nqdA:
undetectable
5z86W-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 ARG A 149
MET A 604
THR A 603
LEU A 600
 None
 1.00A 5zcoN-5nqdA:
undetectable
5zcoW-5nqdA:
undetectable		 5zcoN-5nqdA:
undetectable
5zcoW-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		3 / 3 PHE A 331
ASP A 330
LYS A 334
 None
 0.86A 6awtD-5nqdA:
undetectable		 6awtD-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		3 / 3 ARG A 447
ARG A 720
ARG A 201
 O  A2003 ( 4.5A)
MGD  A2001 ( 3.3A)
None
 1.07A 6bplA-5nqdA:
undetectable
6bplB-5nqdA:
undetectable		 6bplA-5nqdA:
18.09
6bplB-5nqdA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 12 VAL A 510
TYR A 490
THR A 493
HIS A 555
GLY A 480
 None
 1.11A 6gngB-5nqdA:
undetectable		 6gngB-5nqdA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 11 VAL A 208
GLY A 210
ALA A 695
ASN A 220
VAL A 216
 None
 1.11A 6hu9A-5nqdA:
undetectable
6hu9E-5nqdA:
0.6
6hu9I-5nqdA:
undetectable		 6hu9A-5nqdA:
undetectable
6hu9E-5nqdA:
undetectable
6hu9I-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		5 / 10 VAL A 208
GLY A 210
ALA A 695
ASN A 220
VAL A 216
 None
 1.13A 6hu9L-5nqdA:
undetectable
6hu9P-5nqdA:
undetectable
6hu9T-5nqdA:
undetectable		 6hu9L-5nqdA:
undetectable
6hu9P-5nqdA:
undetectable
6hu9T-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 5 ARG A 149
MET A 604
THR A 603
LEU A 600
 None
 0.97A 6nknW-5nqdA:
undetectable		 6nknW-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.88A 6nmfA-5nqdA:
undetectable
6nmfJ-5nqdA:
undetectable		 6nmfA-5nqdA:
undetectable
6nmfJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.34A 6nmfN-5nqdA:
undetectable
6nmfP-5nqdA:
undetectable		 6nmfN-5nqdA:
undetectable
6nmfP-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 LEU A 163
ARG A 149
MET A 604
THR A 603
 None
 1.00A 6nmfN-5nqdA:
undetectable
6nmfW-5nqdA:
undetectable		 6nmfN-5nqdA:
undetectable
6nmfW-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 6 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.30A 6nmpA-5nqdA:
undetectable
6nmpC-5nqdA:
undetectable		 6nmpA-5nqdA:
undetectable
6nmpC-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 LEU A 163
ARG A 149
MET A 604
LEU A 600
 None
 0.96A 6nmpA-5nqdA:
undetectable
6nmpJ-5nqdA:
undetectable		 6nmpA-5nqdA:
undetectable
6nmpJ-5nqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE
(Rhizobium
sp.
NT-26) 		4 / 7 HIS A 482
ASP A 508
THR A 507
HIS A 489
 None
 1.37A 6nmpN-5nqdA:
undetectable
6nmpP-5nqdA:
undetectable		 6nmpN-5nqdA:
undetectable
6nmpP-5nqdA:
undetectable