SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ns8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 5ns8 -
(-) 		3 / 3 ALA A  90
VAL A  83
TRP A  80
 None
 0.88A 1c4dC-5ns8A:
undetectable
1c4dD-5ns8A:
undetectable		 1c4dC-5ns8A:
undetectable
1c4dD-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 5ns8 -
(-) 		4 / 4 HIS A 173
ALA A 169
PHE A 166
GLY A 172
 None
 1.35A 1mj2B-5ns8A:
undetectable		 1mj2B-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 5ns8 -
(-) 		4 / 4 HIS A 173
ALA A 169
PHE A 166
GLY A 172
 None
 1.33A 1mj2D-5ns8A:
undetectable		 1mj2D-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 5ns8 -
(-) 		4 / 4 HIS A 173
ALA A 169
PHE A 166
GLY A 172
 None
 1.35A 1mjoB-5ns8A:
undetectable		 1mjoB-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 5ns8 -
(-) 		4 / 4 HIS A 173
ALA A 169
PHE A 166
GLY A 172
 None
 1.34A 1mjoA-5ns8A:
undetectable		 1mjoA-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)		 5ns8 -
(-) 		4 / 4 HIS A 173
ALA A 169
PHE A 166
GLY A 172
 None
 1.33A 1mjoD-5ns8A:
undetectable		 1mjoD-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_A_PAUA6001_0
(PANTOTHENATE KINASE)		 5ns8 -
(-) 		5 / 9 ASP A 275
GLY A 200
HIS A 193
LEU A 201
ILE A 162
 None
 1.29A 1sq5A-5ns8A:
undetectable		 1sq5A-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_B_PAUB6003_0
(PANTOTHENATE KINASE)		 5ns8 -
(-) 		5 / 10 ASP A 275
GLY A 200
HIS A 193
LEU A 201
ILE A 162
 None
 1.33A 1sq5B-5ns8A:
undetectable		 1sq5B-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_C_PAUC6002_0
(PANTOTHENATE KINASE)		 5ns8 -
(-) 		5 / 9 ASP A 275
GLY A 200
HIS A 193
LEU A 201
ILE A 162
 None
 1.34A 1sq5C-5ns8A:
undetectable		 1sq5C-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 5ns8 -
(-) 		5 / 10 ASP A 275
GLY A 200
HIS A 193
LEU A 201
ILE A 162
 None
 1.32A 1sq5D-5ns8A:
undetectable		 1sq5D-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 5ns8 -
(-) 		5 / 12 SER A  15
ILE A  19
LEU A  65
GLY A 412
VAL A 416
 NOJ  A 506 ( 4.0A)
None
SO4  A 502 ( 4.9A)
None
None
 1.14A 1tsnA-5ns8A:
undetectable		 1tsnA-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 5ns8 -
(-) 		4 / 4 LEU A 305
PRO A 306
LEU A 239
ARG A 246
 GOL  A 504 (-3.6A)
None
None
None
 1.26A 2qd2A-5ns8A:
undetectable		 2qd2A-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 5ns8 -
(-) 		4 / 5 LEU A 305
PRO A 306
LEU A 239
ILE A 261
 GOL  A 504 (-3.6A)
None
None
None
 0.84A 2qd4A-5ns8A:
undetectable		 2qd4A-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 5ns8 -
(-) 		5 / 11 ASN A 163
GLU A 164
TYR A 291
GLU A 349
TRP A 395
 NOJ  A 506 (-3.1A)
NOJ  A 506 (-2.5A)
NOJ  A 506 (-3.8A)
NOJ  A 506 (-2.6A)
NOJ  A 506 (-3.2A)
 0.82A 2v3dB-5ns8A:
18.1		 2v3dB-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 5ns8 -
(-) 		4 / 6 SER A  16
VAL A  83
TYR A  99
ASP A 121
 None
 1.40A 2x45A-5ns8A:
undetectable		 2x45A-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5ns8 -
(-) 		5 / 12 ILE A 103
TYR A  99
PHE A  98
LEU A  63
PRO A 113
 None
 1.12A 2y7kD-5ns8A:
undetectable		 2y7kD-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5ns8 -
(-) 		5 / 12 PHE A 248
TYR A 307
LEU A 239
LEU A 174
TYR A 175
 None
GOL  A 504 (-3.3A)
None
None
GOL  A 504 (-4.4A)
 1.37A 3adxA-5ns8A:
undetectable		 3adxA-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_2
(RENIN)		 5ns8 -
(-) 		4 / 5 TYR A 415
ALA A 353
ALA A 429
TYR A 432
 None
 1.24A 3d91A-5ns8A:
undetectable		 3d91A-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_1
(DIHYDROFOLATE
REDUCTASE)		 5ns8 -
(-) 		5 / 12 ALA A  79
GLU A  20
PHE A  76
ILE A 103
TYR A 144
 None
 1.33A 3ia4C-5ns8A:
undetectable		 3ia4C-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 5ns8 -
(-) 		4 / 7 ASN A  60
LEU A  63
ASP A  64
LYS A  67
 None
 0.97A 3lslA-5ns8A:
undetectable
3lslD-5ns8A:
undetectable		 3lslA-5ns8A:
undetectable
3lslD-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 5ns8 -
(-) 		4 / 7 ASN A  60
LEU A  63
ASP A  64
LYS A  67
 None
 0.97A 3lslA-5ns8A:
undetectable
3lslD-5ns8A:
undetectable		 3lslA-5ns8A:
undetectable
3lslD-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 5ns8 -
(-) 		4 / 6 ASN A  60
LEU A  63
ASP A  64
LYS A  67
 None
 0.93A 3lslG-5ns8A:
undetectable		 3lslG-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ns8 -
(-) 		5 / 9 ALA A  73
ASN A 289
ILE A 347
GLU A 349
THR A  14
 None
NOJ  A 506 ( 4.6A)
None
NOJ  A 506 (-2.6A)
None
 1.15A 3rukC-5ns8A:
undetectable		 3rukC-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOF_A_HQEA200_1
(FLAVOREDOXIN)		 5ns8 -
(-) 		4 / 5 TYR A 257
VAL A 269
ARG A 135
HIS A 194
 None
 1.37A 3zofA-5ns8A:
undetectable		 3zofA-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOF_B_HQEB200_1
(FLAVOREDOXIN)		 5ns8 -
(-) 		4 / 5 TYR A 257
VAL A 269
ARG A 135
HIS A 194
 None
 1.33A 3zofB-5ns8A:
0.0		 3zofB-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5ns8 -
(-) 		4 / 7 PRO A 180
ILE A  32
GLN A 127
GLY A 131
 None
 0.96A 4a3uB-5ns8A:
14.0		 4a3uB-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5ns8 -
(-) 		5 / 12 LEU A 333
LEU A 376
ILE A 347
TYR A 392
TYR A 431
 None
 1.33A 4a79A-5ns8A:
undetectable		 4a79A-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5ns8 -
(-) 		5 / 11 LEU A 333
LEU A 376
ILE A 347
TYR A 392
TYR A 431
 None
 1.31A 4a7aA-5ns8A:
undetectable		 4a7aA-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 5ns8 -
(-) 		4 / 5 ILE A  78
ILE A  84
TYR A 144
GLU A 143
 None
 1.20A 4a99D-5ns8A:
undetectable		 4a99D-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ns8 -
(-) 		4 / 4 LEU A 305
PRO A 306
LEU A 239
ILE A 261
 GOL  A 504 (-3.6A)
None
None
None
 0.87A 4f4dB-5ns8A:
undetectable		 4f4dB-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ns8 -
(-) 		4 / 6 PHE A 152
LEU A  91
VAL A  83
ASP A 100
 None
 1.15A 4g3rA-5ns8A:
undetectable		 4g3rA-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ns8 -
(-) 		4 / 5 LEU A 305
PRO A 306
LEU A 239
ILE A 261
 GOL  A 504 (-3.6A)
None
None
None
 0.90A 4klrA-5ns8A:
undetectable		 4klrA-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 5ns8 -
(-) 		3 / 3 ASP A 121
TRP A 395
SER A  77
 None
NOJ  A 506 (-3.2A)
None
 1.03A 4lrhB-5ns8A:
undetectable		 4lrhB-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QE6_A_JN3A1001_1
(BILE ACID RECEPTOR)		 5ns8 -
(-) 		5 / 12 MET A 148
ALA A 149
ARG A 155
ILE A 103
TYR A 285
 None
 1.14A 4qe6A-5ns8A:
undetectable		 4qe6A-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 5ns8 -
(-) 		5 / 12 ALA A  52
ALA A  44
GLY A 406
PHE A 401
TYR A 407
 None
 1.27A 4r29A-5ns8A:
undetectable		 4r29A-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 5ns8 -
(-) 		5 / 12 ALA A  52
ALA A  44
GLY A 406
PHE A 401
TYR A 407
 None
 1.22A 4r29B-5ns8A:
undetectable		 4r29B-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 5ns8 -
(-) 		5 / 12 ALA A  52
ALA A  44
GLY A 406
PHE A 401
TYR A 407
 None
 1.26A 4r29C-5ns8A:
undetectable		 4r29C-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5ns8 -
(-) 		5 / 12 PRO A 115
ILE A 162
VAL A 215
PHE A 141
THR A 281
 None
 1.29A 5bykA-5ns8A:
undetectable		 5bykA-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5ns8 -
(-) 		5 / 12 VAL A  43
SER A  37
PHE A 401
ALA A  23
VAL A  51
 None
 1.12A 5n0oA-5ns8A:
undetectable		 5n0oA-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5ns8 -
(-) 		5 / 12 VAL A  43
SER A  37
PHE A 401
ALA A  23
VAL A  51
 None
 1.13A 5n0sB-5ns8A:
undetectable		 5n0sB-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 5ns8 -
(-) 		4 / 6 LEU A 102
PHE A  98
ASP A  97
HIS A  57
 None
 1.01A 5om3A-5ns8A:
undetectable
5om3B-5ns8A:
undetectable		 5om3A-5ns8A:
undetectable
5om3B-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 5ns8 -
(-) 		5 / 11 PRO A 115
ILE A 162
PHE A 141
SER A 145
LEU A 219
 None
 1.48A 5tiyA-5ns8A:
undetectable		 5tiyA-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5ns8 -
(-) 		4 / 8 GLU A 339
PHE A 243
SER A 192
PHE A 265
 None
 1.07A 5y2tB-5ns8A:
undetectable		 5y2tB-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5ns8 -
(-) 		6 / 12 PRO A 115
ILE A 162
LEU A 196
PHE A 141
SER A 145
LEU A 219
 None
 1.49A 6b52A-5ns8A:
undetectable		 6b52A-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5ns8 -
(-) 		5 / 10 SER A 192
LEU A 305
LEU A 174
ASP A 184
ILE A 261
 None
GOL  A 504 (-3.6A)
None
None
None
 1.32A 6dlzB-5ns8A:
undetectable
6dlzC-5ns8A:
undetectable		 6dlzB-5ns8A:
undetectable
6dlzC-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5ns8 -
(-) 		5 / 11 ILE A 261
SER A 192
LEU A 305
LEU A 174
ASP A 184
 None
None
GOL  A 504 (-3.6A)
None
None
 1.32A 6dlzA-5ns8A:
undetectable
6dlzD-5ns8A:
undetectable		 6dlzA-5ns8A:
undetectable
6dlzD-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5ns8 -
(-) 		5 / 10 SER A 192
LEU A 305
LEU A 174
ASP A 184
ILE A 261
 None
GOL  A 504 (-3.6A)
None
None
None
 1.32A 6dm1B-5ns8A:
undetectable
6dm1C-5ns8A:
undetectable		 6dm1B-5ns8A:
undetectable
6dm1C-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5ns8 -
(-) 		5 / 11 ILE A 261
SER A 192
LEU A 305
LEU A 174
ASP A 184
 None
None
GOL  A 504 (-3.6A)
None
None
 1.31A 6dm1A-5ns8A:
undetectable
6dm1D-5ns8A:
undetectable		 6dm1A-5ns8A:
undetectable
6dm1D-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5ns8 -
(-) 		5 / 10 SER A 192
LEU A 305
LEU A 174
ASP A 184
ILE A 261
 None
GOL  A 504 (-3.6A)
None
None
None
 1.33A 6dm2B-5ns8A:
undetectable
6dm2C-5ns8A:
undetectable		 6dm2B-5ns8A:
undetectable
6dm2C-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 5ns8 -
(-) 		4 / 7 ASN A 384
GLY A 391
VAL A 336
LEU A 333
 None
 0.77A 6dwnB-5ns8A:
undetectable		 6dwnB-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 5ns8 -
(-) 		3 / 3 TYR A  59
HIS A  55
PHE A  98
 None
 0.92A 6esmA-5ns8A:
undetectable		 6esmA-5ns8A:
undetectable